Patents by Inventor Seth Porter

Seth Porter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND COMPOSITION FOR ADMINISTERING AN NMDA RECEPTOR ANTAGONIST TO A SUBJECT
    Publication number: 20100260838
    Abstract: The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject.
    Type: Application
    Filed: April 9, 2010
    Publication date: October 14, 2010
    Applicant: Adamas Pharmaceuticals, Inc.
    Inventors: Gregory T. Went, Timothy J. Fultz, Seth Porter, Laurence R. Meyerson, Timothy S. Burkoth
  • Method and Composition for Administering an NMDA Receptor Antagonist to a Subject
    Publication number: 20100047342
    Abstract: The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject.
    Type: Application
    Filed: July 30, 2009
    Publication date: February 25, 2010
    Applicant: ADAMAS PHARMACEUTICALS, INC.
    Inventors: Gregory T. Went, Timothy J. Fultz, Seth Porter, Laurence R. Meyerson, Timothy S. Burkoth
  • Composition and method for treating neurological disease
    Publication number: 20060189694
    Abstract: The invention provides methods and compositions for treating or preventing neurological disorders.
    Type: Application
    Filed: November 23, 2005
    Publication date: August 24, 2006
    Inventors: Gregory Went, Timothy Fultz, Seth Porter, Laurence Meyerson, Timothy Burkoth
  • Method and composition for adminstering an NMDA receptor antagonist to a subject
    Publication number: 20060142398
    Abstract: The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject.
    Type: Application
    Filed: November 22, 2005
    Publication date: June 29, 2006
    Inventors: Gregory Went, Timothy Fultz, Seth Porter, Laurence Meyerson, Timothy Burkoth
  • Blood-brain barrier model
    Patent number: 5260210
    Abstract: An in vitro model of a blood-brain barrier comprising a porous solid support upon which is disposed an essentially confluent monolayer of brain microvascular endothelial cells in contact with agents that elevate effective cyclic AMP concentrations in endothelial cells, with or without astrocyte-derived or endothelial cell-derived conditioned medium or the equivalent so that high electrical resistance tight junctions are formed between endothelial cells, and endothelial cells exhibit peripheral phalloidin staining and E-cadherin. Also disclosed is the use of agents that reduce effective cyclic AMP concentrations or interfere with the functioning of cyclic AMP or increase effective cyclic GMP concentrations to open up blood-brain barriers in vitro and in vivo, so that drugs normally excluded by such barriers may substantially penetrate such barriers. Also disclosed are uses of the model to screen for reagents with clinical utility in disorders involving brain endothelial cells.
    Type: Grant
    Filed: September 4, 1990
    Date of Patent: November 9, 1993
    Inventors: Lee L. Rubin, Seth Porter, Heidi C. Horner, Theodore A. Yednick