Patents by Inventor Seth R. Abbott

Seth R. Abbott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Strong anion exchange composition and methods
    Patent number: 4430496
    Abstract: A strong anion exchange composition useful in monophosphate nucleotide isomer separations is comprised of an inert porous particle having a silyl alkyl ammonium compound fixedly attached by a covalent silicon-oxygen-silicon bond to the surface thereof. A process for synthesizing the strong anion exchange composition in an aqueous solvent is disclosed together with methods for separation of monophosphate nucleotide isomers, highly phophorylated nucleotides and aldopentose carbohydrates using a column packed with this strong anion exchange composition.
    Type: Grant
    Filed: March 16, 1982
    Date of Patent: February 7, 1984
    Assignee: Varian Associates, Inc.
    Inventor: Seth R. Abbott
  • Fluorescent composition, a process for synthesizing the fluorescent composition
    Patent number: 4396528
    Abstract: A fluorescent composition useful in thin-layer chromatography comprises an inert porous particle having a fluorescent material fixedly attached by covalent chemical bonding to the surface thereof. A process for synthesizing this fluorescent composition is disclosed. A method for detecting the radioactivity of a radioactive species using a cell packed with such a fluorescent composition is also disclosed.
    Type: Grant
    Filed: June 9, 1981
    Date of Patent: August 2, 1983
    Assignee: Varian Associates, Inc.
    Inventor: Seth R. Abbott
  • Fluorescence enhancement of dansyl derivatives
    Patent number: 4378500
    Abstract: A method for fluorescence enhancement of dansyl derivatives of active hydrogen compounds which are easily separated in a liquid chromatography column using a polar solvent system but whose fluorescence efficiency is diminished in such polar solvents, by changing the environment of the dansyl derivative without changing the solvent.
    Type: Grant
    Filed: March 10, 1981
    Date of Patent: March 29, 1983
    Assignee: Varian Associates, Inc.
    Inventors: Seth R. Abbott, Robert Cunico
  • Anion exchange chromatographic composition for separation of polyfunctional compounds
    Patent number: 4340496
    Abstract: A weak anion exchange composition useful in polyfunctional compound chromatographic separations comprises an inert porous particle having a tetra-substituted silane material fixedly attached by covalent bonding to the surface thereof. A process for synthesizing the weak anion exchange composition is disclosed together with methods for separation of polyfunctional compounds and their isomers using a column packed with such weak anion exchange composition.
    Type: Grant
    Filed: June 9, 1981
    Date of Patent: July 20, 1982
    Assignee: Varian Associates, Inc.
    Inventor: Seth R. Abbott
  • Strong anion exchange composition
    Patent number: 4322542
    Abstract: A strong anion exchange composition useful in monophosphate nucleotide isomer separations is comprised of an inert porous particle having a silyl alkyl ammonium compound fixedly attached by a covalent silicon-oxygen-silicon bond to the surface thereof. A process for synthesizing the strong anion exchange composition in an aqueous solvent is disclosed together with methods for separation of monophosphate nucleotide isomers, highly phosphorylated nucleotides and aldopentose carbohydrates using a column packed with this strong anion exchange composition.
    Type: Grant
    Filed: January 17, 1980
    Date of Patent: March 30, 1982
    Assignee: Varian Associates, Inc.
    Inventor: Seth R. Abbott
  • Mixed phase chromatographic compositions
    Patent number: 4298500
    Abstract: The mixed phase packing material of this invention, enables rapid separation of multi-sited biopolymers. This separation is achieved by "tailoring" the distance between organo-silyl groups covalently bonded to the rigid support at the Angstrom distance needed for reversible separation of the biopolymers of interest and "capping" other sterically available active sites on the support with a relatively inert compound.
    Type: Grant
    Filed: May 5, 1980
    Date of Patent: November 3, 1981
    Assignee: Varian Associates, Inc.
    Inventor: Seth R. Abbott
  • Anion exchange chromatographic separation of polyfunctional compounds
    Patent number: 4290892
    Abstract: A weak anion exchange composition useful in polyfunctional compound chromatographic separations comprises an inert porous particle having a tetra-substituted silane material fixedly attached by covalent bonding to the surface thereof. A process for synthesizing the weak anion exchange composition is disclosed together with methods for separation of polyfunctional compounds and their isomers using a column packed with such weak anion exchange composition.
    Type: Grant
    Filed: March 2, 1979
    Date of Patent: September 22, 1981
    Assignee: Varian Associates, Inc.
    Inventor: Seth R. Abbott
  • Fluorescent composition, a process for synthesizing the fluorescent composition, and methods of use of the fluorescent composition
    Patent number: 4275300
    Abstract: A fluorescent composition useful in thin-layer chromatography comprises an inert porous particle having a fluorescent material fixedly attached by covalent chemical bonding to the surface thereof. A process for synthesizing this fluorescent composition is disclosed. A method for detecting the radioactivity of a radioactive species using a cell packed with such a fluorescent composition is also disclosed.
    Type: Grant
    Filed: October 23, 1978
    Date of Patent: June 23, 1981
    Assignee: Varian Associates, Inc.
    Inventor: Seth R. Abbott