Patents by Inventor Seth Wardell

Seth Wardell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11202803
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: December 21, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11202804
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: December 21, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210379111
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: July 22, 2021
    Publication date: December 9, 2021
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210361712
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: July 22, 2021
    Publication date: November 25, 2021
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210361713
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: July 22, 2021
    Publication date: November 25, 2021
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210353677
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: July 22, 2021
    Publication date: November 18, 2021
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11168304
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: November 9, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11168303
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: November 9, 2021
    Assignee: Iovance Biotherapeutics
    Inventors: Seth Wardell, James Bender
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11083752
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: August 10, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210214685
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: January 12, 2021
    Publication date: July 15, 2021
    Inventors: Seth Wardell, James Bender
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210207091
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: January 13, 2021
    Publication date: July 8, 2021
    Inventors: Seth Wardell, James Bender
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210207092
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: January 13, 2021
    Publication date: July 8, 2021
    Inventors: Seth Wardell, James Bender
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11052115
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: July 6, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11052116
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: July 6, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11040070
    Abstract: The present invention provides improved and/or shortened methods for expanding TLs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TLs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TLs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: June 22, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11013770
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: May 25, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11007225
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: May 18, 2021
    Assignee: lovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
    Patent number: 11007226
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: May 18, 2021
    Assignee: Iovance Biotherapeutics, Inc.
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210137984
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: December 18, 2020
    Publication date: May 13, 2021
    Inventors: Seth Wardell, James Bender, Michael T. Lotze
  • PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
    Publication number: 20210128623
    Abstract: The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 6, 2021
    Inventors: Seth Wardell, James Bender, Michael T. Lotze