Patents by Inventor Setsuko Katoh

Setsuko Katoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant co-expression system of protein disulfide isomerase gene, yeast receptor protein ERD2 gene and a foreign product polypeptide gene, and a process for producing the foreign polypeptide using such system
    Patent number: 5578466
    Abstract: The present invention is directed to a transformant comprising the following expression units in a co-expressible state:an expression unit containing a gene coding for a receptor protein ERD2 from yeast or analog thereof which is capable of binding to a protein localizing in endoplasmic reticulum and having a signal for staying therein;an expression unit containing a gene coding for said protein localizing in endoplasmic reticulum; andan expression unit containing a foreign gene coding for a polypeptide which is a subject of function of said protein localizing in endoplasmic reticulum, andto a transformant comprising, in a co-expressible state, a fusion gene which is composed of a DNA fragment coding for a human serum albumin prepro-sequence and a foreign gene coding for a useful polypeptide. The present invention is also directed to a process for producing said polypeptide by co-expressing said genes in said transformant such that the polypeptide is predominantly secreted out of the transformant cell.
    Type: Grant
    Filed: April 17, 1992
    Date of Patent: November 26, 1996
    Assignee: Tonen Corporation
    Inventors: Toshiya Hayano, Setsuko Katoh, Nobuhiro Takahashi, Masanori Suzuki, Keiichi Honma