Patents by Inventor Seul Ki YEON
Seul Ki YEON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12234207Abstract: The present invention relates to a novel halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative or a pharmaceutically acceptable salt thereof; a preparation method thereof; and an Nrf2 activator and a pharmaceutical composition for preventing or treating diseases induced by a decrease in Nrf2 activity, both of which comprise the same as an active ingredient.Type: GrantFiled: August 19, 2019Date of Patent: February 25, 2025Assignee: CUREVERSE INCORPORATEDInventors: Ki Duk Park, Ae Nim Pae, Sang Min Lim, Jong Hyun Park, Ji Won Choi, Siwon Kim, Hyeon Jeong Kim, Seul Ki Yeon
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Publication number: 20250034084Abstract: The present invention relates to novel functional derivatives of alanine and proline amino acids. The compounds of the present invention were confirmed to have a very superior antifungal or fungicidal effect. In addition, the compounds of the present invention were confirmed to exhibit a synergistic effect when co-administered with an existing antifungal preparation. Moreover, the compounds of the present invention showed activity on a wide range of fungi. Therefore, the compounds of the present invention can be widely used in a field which requires the treatment with an antifungal or fungicidal preparation against human infectious fungi, animal infectious fungi, and phytopathogenic fungi.Type: ApplicationFiled: October 17, 2024Publication date: January 30, 2025Inventors: Ki Duk PARK, Yong-Sun BAHN, Jong-Seung LEE, Kyung-Tae LEE, Ae Nim PAE, Seul Ki YEON, Yong Koo KANG, Jong Hyun PARK, Siwon KIM, Bo Ko JANG, Ji Won CHOI
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Publication number: 20250034083Abstract: The present invention relates to novel functional derivatives of alanine and proline amino acids. The compounds of the present invention were confirmed to have a very superior antifungal or fungicidal effect. In addition, the compounds of the present invention were confirmed to exhibit a synergistic effect when co-administered with an existing antifungal preparation. Moreover, the compounds of the present invention showed activity on a wide range of fungi. Therefore, the compounds of the present invention can be widely used in a field which requires the treatment with an antifungal or fungicidal preparation against human infectious fungi, animal infectious fungi, and phytopathogenic fungi.Type: ApplicationFiled: October 17, 2024Publication date: January 30, 2025Inventors: Ki Duk PARK, Yong-Sun BAHN, Jong-Seung LEE, Kyung-Tae LEE, Ae Nim PAE, Seul Ki YEON, Yong Koo KANG, Jong Hyun PARK, Siwon KIM, Bo Ko JANG, Ji Won CHOI
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Publication number: 20250034082Abstract: The present invention relates to novel functional derivatives of alanine and proline amino acids. The compounds of the present invention were confirmed to have a very superior antifungal or fungicidal effect. In addition, the compounds of the present invention were confirmed to exhibit a synergistic effect when co-administered with an existing antifungal preparation. Moreover, the compounds of the present invention showed activity on a wide range of fungi. Therefore, the compounds of the present invention can be widely used in a field which requires the treatment with an antifungal or fungicidal preparation against human infectious fungi, animal infectious fungi, and phytopathogenic fungi.Type: ApplicationFiled: October 17, 2024Publication date: January 30, 2025Inventors: Ki Duk PARK, Yong-Sun BAHN, Jong-Seung LEE, Kyung-Tae LEE, Ae Nim PAE, Seul Ki YEON, Yong Koo KANG, Jong Hyun PARK, Siwon KIM, Bo Ko JANG, Ji Won CHOI
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Publication number: 20250034085Abstract: The present invention relates to novel functional derivatives of alanine and proline amino acids. The compounds of the present invention were confirmed to have a very superior antifungal or fungicidal effect. In addition, the compounds of the present invention were confirmed to exhibit a synergistic effect when co-administered with an existing antifungal preparation. Moreover, the compounds of the present invention showed activity on a wide range of fungi. Therefore, the compounds of the present invention can be widely used in a field which requires the treatment with an antifungal or fungicidal preparation against human infectious fungi, animal infectious fungi, and phytopathogenic fungi.Type: ApplicationFiled: October 17, 2024Publication date: January 30, 2025Inventors: Ki Duk PARK, Yong-Sun BAHN, Jong-Seung LEE, Kyung-Tae LEE, Ae Nim PAE, Seul Ki YEON, Yong Koo KANG, Jong Hyun PARK, Siwon KIM, Bo Ko JANG, Ji Won CHOI
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Patent number: 12180139Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: GrantFiled: September 19, 2022Date of Patent: December 31, 2024Assignee: AMTIXBIO CO., LTD.Inventors: Ki Duk Park, Jong Hyun Park, Hyeon Ji Kim, Ye Rim Lee, Siwon Kim, Ji Won Choi, Seul Ki Yeon, Jong-Seung Lee, Yong-Sun Bahn, Eunji Cheong, Kyung-Tae Lee, Joohyeon Hong
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Patent number: 12172945Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: GrantFiled: September 19, 2022Date of Patent: December 24, 2024Assignee: AMTIXBIO CO., LTD.Inventors: Ki Duk Park, Jong Hyun Park, Hyeon Ji Kim, Ye Rim Lee, Siwon Kim, Ji Won Choi, Seul Ki Yeon, Jong-Seung Lee, Yong-Sun Bahn, Eunji Cheong, Kyung-Tae Lee, Joohyeon Hong
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Patent number: 12129220Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: GrantFiled: September 19, 2022Date of Patent: October 29, 2024Assignee: AMTIXBIO CO., LTD.Inventors: Ki Duk Park, Jong Hyun Park, Hyeon Ji Kim, Ye Rim Lee, Siwon Kim, Ji Won Choi, Seul Ki Yeon, Jong-Seung Lee, Yong-Sun Bahn, Eunji Cheong, Kyung-Tae Lee, Joohyeon Hong
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Publication number: 20230067422Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: ApplicationFiled: September 19, 2022Publication date: March 2, 2023Inventors: Ki Duk PARK, Jong Hyun PARK, Hyeon Ji KIM, Ye Rim LEE, Siwon KIM, Ji Won CHOI, Seul Ki YEON, Jong-Seung LEE, Yong-Sun BAHN, Eunji CHEONG, Kyung-Tae LEE, Joohyeon HONG
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Publication number: 20230053855Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: ApplicationFiled: September 19, 2022Publication date: February 23, 2023Inventors: Ki Duk PARK, Jong Hyun PARK, Hyeon Ji KIM, Ye Rim LEE, Siwon KIM, Ji Won CHOI, Seul Ki YEON, Jong-Seung LEE, Yong-Sun BAHN, Eunji CHEONG, Kyung-Tae LEE, Joohyeon HONG
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Publication number: 20230056812Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: ApplicationFiled: September 19, 2022Publication date: February 23, 2023Inventors: Ki Duk PARK, Jong Hyun PARK, Hyeon Ji KIM, Ye Rim LEE, Siwon KIM, Ji Won CHOI, Seul Ki YEON, Jong-Seung LEE, Yong-Sun BAHN, Eunji CHEONG, Kyung-Tae LEE, Joohyeon HONG
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Patent number: 11479526Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: GrantFiled: December 27, 2021Date of Patent: October 25, 2022Assignee: AMTIXBIO CO., LTD.Inventors: Ki Duk Park, Jong Hyun Park, Hyeon Ji Kim, Ye Rim Lee, Siwon Kim, Ji Won Choi, Seul Ki Yeon, Jong-Seung Lee, Yong-Sun Bahn, Eunji Cheong, Kyung-Tae Lee, Joohyeon Hong
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Publication number: 20220144755Abstract: The present invention relates to a derivative compound in which a biphenyl group is introduced into an aminoalkanoic acid, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound of the present invention exhibits excellent antifungal and fungicidal effects. Furthermore, the compound of the present invention exhibits a synergistic effect when used in combination with a conventional antifungal agent. Furthermore, the compound of the present invention provides broad-spectrum antifungal activity against a wide range of fungal pathogens. Therefore, the compound of the present invention may be widely used in fields requiring treatment with antifungal or fungicidal agents against human pathogenic fungi and animal pathogenic fungi, and phytopathogenic fungi.Type: ApplicationFiled: December 27, 2021Publication date: May 12, 2022Inventors: Ki Duk PARK, Jong Hyun Park, Hyeon Ji Kim, Ye Rim Lee, Siwon Kim, Ji Won Choi, Seul Ki Yeon, Jong-Seung Lee, Yong-Sun Bahn, Eunji Cheong, Kyung-Tae Lee, Joohyeon Hong
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Publication number: 20210317083Abstract: The present invention relates to a novel halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative or a pharmaceutically acceptable salt thereof; a preparation method thereof; and an Nrf2 activator and a pharmaceutical composition for preventing or treating diseases induced by a decrease in Nrf2 activity, both of which comprise the same as an active ingredient.Type: ApplicationFiled: August 19, 2019Publication date: October 14, 2021Inventors: Ki Duk PARK, Ae Nim PAE, Sang Min LIM, Jong Hyun PARK, Ji Won CHOI, Siwon KIM, Hyeon Jeong KIM, Seul Ki YEON
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Patent number: 11053190Abstract: The present disclosure relates to an ?-aminoamide derivative compound and a pharmaceutical composition containing the same. According to various embodiments of the present disclosure, provided is a therapeutic agent which can overcome the disadvantages of existing drugs used as a MAO-B inhibitor and, specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of the existing drugs which exhibit a therapeutic effect by irreversibly acting via a covalent bond with MAO-B. Particularly, a new compound having superior stability and efficacy compared to the existing reversible MAO-B inhibitors may be provided.Type: GrantFiled: April 24, 2020Date of Patent: July 6, 2021Assignee: NeuroBiogen Co., Ltd.Inventors: Ki Duk Park, ChangJoon Justin Lee, Dong Jin Kim, Ae Nim Pae, Hyun Ah Choo, Sun Joon Min, Yong Koo Kang, Yun Kyung Kim, Hyo Jung Song, Ji Won Choi, Min Ho Nam, Jun Young Heo, Seul Ki Yeon, Bo Ko Jang, Eun Ji Ju, Seon Mi Jo, Jong-Hyun Park
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Publication number: 20200308104Abstract: The present disclosure relates to an ?-aminoamide derivative compound and a pharmaceutical composition containing the same. According to various embodiments of the present disclosure, provided is a therapeutic agent which can overcome the disadvantages of existing drugs used as a MAO-B inhibitor and, specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of the existing drugs which exhibit a therapeutic effect by irreversibly acting via a covalent bond with MAO-B. Particularly, a new compound having superior stability and efficacy compared to the existing reversible MAO-B inhibitors may be provided.Type: ApplicationFiled: April 24, 2020Publication date: October 1, 2020Inventors: Ki Duk PARK, ChangJoon Justin LEE, Dong Jin KIM, Ae Nim PAE, Hyun Ah CHOO, Sun Joon MIN, Yong Koo KANG, Yun Kyung KIM, Hyo Jung SONG, Ji Won CHOI, Min Ho NAM, Jun Young HEO, Seul Ki YEON, Bo Ko JANG, Eun Ji JU, Seon Mi JO, Jong-Hyun PARK
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Publication number: 20200199065Abstract: The present invention relates to novel functional derivatives of alanine and proline amino acids. The compounds of the present invention were confirmed to have a very superior antifungal or fungicidal effect. In addition, the compounds of the present invention were confirmed to exhibit a synergistic effect when co-administered with an existing antifungal preparation. Moreover, the compounds of the present invention showed activity on a wide range of fungi. Therefore, the compounds of the present invention can be widely used in a field which requires the treatment with an antifungal or fungicidal preparation against human infectious fungi, animal infectious fungi, and phytopathogenic fungi.Type: ApplicationFiled: October 30, 2017Publication date: June 25, 2020Inventors: Ki Duk Park, Yong-Sun Bahn, Jong-Seung Lee, Kyung-Tae Lee, Ae Nim Pae, Seul Ki Yeon, Yong Koo Kang, Jong Hyun Park, Siwon Kim, Bo Ko Jang, Ji Won Choi
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Patent number: 10676425Abstract: The present disclosure relates to an ?-aminoamide derivative compound and a pharmaceutical composition containing the same, for treating a neurodegenerative diseases.Type: GrantFiled: September 24, 2015Date of Patent: June 9, 2020Assignee: MEGABIOWOOD CO., LTDInventors: Ki Duk Park, ChangJoon Justin Lee, Dong Jin Kim, Ae Nim Pae, Hyun Ah Choo, Sun Joon Min, Yong Koo Kang, Yun Kyung Kim, Hyo Jung Song, Ji Won Choi, Min Ho Nam, Jun Young Heo, Seul Ki Yeon, Bo Ko Jang, Eun Ji Ju, Seon Mi Jo, Jong-Hyun Park
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Publication number: 20170298011Abstract: The present disclosure relates to an ?-aminoamide derivative compound and a pharmaceutical composition containing the same. According to various embodiments of the present disclosure, provided is a therapeutic agent which can overcome the disadvantages of existing drugs used as a MAO-B inhibitor and, specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of the existing drugs which exhibit a therapeutic effect by irreversibly acting via a covalent bond with MAO-B. Particularly, a new compound having superior stability and efficacy compared to the existing reversible MAO-B inhibitors may be provided.Type: ApplicationFiled: September 24, 2015Publication date: October 19, 2017Inventors: Ki Duk PARK, ChangJoon Justin LEE, Dong Jin KIM, Ae Nim PAE, Hyun Ah CHOO, Sun Joon MIN, Yong Koo KANG, Yun Kyung KIM, Hyo Jung SONG, Ji Won CHOI, Min Ho NAM, Jun Young HEO, Seul Ki YEON, Bo Ko JANG, Eun Ji JU, Seon Mi JO, Jong-Hyun PARK