Patents by Inventor Seul Ki Cho

Seul Ki Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9777060
    Abstract: The present invention relates to a novel antibody specifically binding to human and mouse L1CAM, and more particularly, to an antibody binding to both human and mouse L1CAM with high affinity, which is prepared by modifying a sequence of an L1 cell adhesion molecule (L1CAM)-specific antibody comprising a heavy-chain variable region of SEQ ID NO. 1 and a light-chain variable region of SEQ ID NO. 5, a polynucleotide encoding the antibody, an expression vector comprising the polynucleotide, a transformant introduced with the vector, a pharmaceutical composition for preventing or treating cancer comprising the antibody, a method for treating cancer using the antibody, a composition for diagnosing cancer comprising the antibody, a kit for diagnosing cancer comprising the composition, a method for providing information for cancer diagnosis using the antibody, and an antibody-drug conjugate prepared by conjugating a drug to the antibody.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: October 3, 2017
    Assignees: KANGWON NATIONAL UNIVERSITY University-Industry Cooperation Foundation, Korea Research Insititute of Bioscience and Biotechnology
    Inventors: Hyo Jeong Hong, In Soo Park, Seul Ki Cho, Mun Sik Jeong, Singh Rohit
  • Publication number: 20150344571
    Abstract: The present invention relates to a novel antibody specifically binding to human and mouse L1CAM, and more particularly, to an antibody binding to both human and mouse L1CAM with high affinity, which is prepared by modifying a sequence of an L1 cell adhesion molecule (L1CAM)-specific antibody comprising a heavy-chain variable region of SEQ ID NO. 1 and a light-chain variable region of SEQ ID NO. 5, a polynucleotide encoding the antibody, an expression vector comprising the polynucleotide, a transformant introduced with the vector, a pharmaceutical composition for preventing or treating cancer comprising the antibody, a method for treating cancer using the antibody, a composition for diagnosing cancer comprising the antibody, a kit for diagnosing cancer comprising the composition, a method for providing information for cancer diagnosis using the antibody, and an antibody-drug conjugate prepared by conjugating a drug to the antibody.
    Type: Application
    Filed: May 18, 2015
    Publication date: December 3, 2015
    Applicants: KANGWON NATIONAL UNIVERSITY University-Industry Cooperation Foundation, Korea Research Institute of Bioscience and Biotechnology
    Inventors: Hyo Jeong HONG, In Soo Park, Seul Ki Cho, Mun Sik Jeong, Singh Rohit