Abstract: The present invention relates to a fusion protein comprising a SARS-CoV-2-derived receptor-binding domain and a nucleocapsid protein, and the use thereof. The fusion protein comprising a coronavirus-derived receptor-binding domain and a nucleocapsid protein is highly applicable to a multivalent vaccine composition having greatly improved in-vivo half-life and remarkably superior efficacy compared to an immunogenic composition comprising only a receptor-binding domain. In particular, the fusion protein can greatly improve the titer of the coronavirus-specific antibody formation and T-cell immune response, and is thus useful for the prevention and treatment of coronaviruses comprising SARS-CoV-2.

Abstract: A method of reinforcement learning of a neural network device for generating a verification vector for verifying a circuit design comprising a circuit block includes inputting a test vector to the circuit block, generating one or more rewards based on a coverage corresponding to the test vector, the coverage being determined based on a state transition of the circuit block based on the test vector, and applying the one or more rewards to a reinforcement learning.

Abstract: The present invention relates to a novel heterocyclic compound usable in an organic light-emitting device and to an organic light-emitting device comprising same, wherein [chemical formula A] is as described in the detailed description of the invention.

Abstract: The present invention relates to stem cell-derived mature cardiomyocytes and a cardiovascular disease model using same and, more specifically, to differentiation into mature ventricular cardiomyocytes by culturing stem cells in a medium containing FGF4 and ascorbic acid, and use of the differentiated mature ventricular cardiomyocytes as a cardiovascular disease cell model. The mature ventricular cardiomyocytes, obtained by culturing stem cells in a medium containing FGF4 and ascorbic acid and inducing the differentiation thereof, and cardiovascular disease cell model using same according to the present invention are very useful for screening for cardiovascular disease therapeutic agents and evaluation of the toxicity of new drugs.

Abstract: An orthodontic wire bending device includes a providing part, a bending unit and a cutting part. The providing part is configured to provide a wire. The bending unit is disposed at a front side of the providing part, and includes a fixing part and a bending part. The fixing part is configured to fix the wire. The bending part is configured to bend the wire fixed by the fixing part. The cutting part is configured to cut the wire bent by the bending part. The bending part includes a bending module, and the bending module is rotated along a circumferential direction or moves along a direction to make contact with at least one side of the wire for bending the wire.

Abstract: A display device includes a base substrate including a display area and a non-display area at a periphery of the display area; a first signal wiring on the non-display area of the base substrate and including a first wiring part and a second wiring part connected to the first wiring part; and a printed circuit board including a lead wiring on the first signal wiring. The second wiring part includes an open part passing through a surface of the second wiring part in a thickness direction, the second wiring part includes a long side extending along a first direction and a short side extending along a second direction intersecting the first direction, and a separation distance between the open part and an end of the short side of the second wiring part in the first direction is within about 0.4 times the long side of the second wiring part.

Abstract: A method of disinfection of a surface of a subject of harmful microorganisms including pathogenic bacteria and viruses upon visible light irradiation using a hybridized fluorescent silk is provided. The method includes placing a predetermined quantity of the hybridized fluorescent silk i) directly on to a skin surface of a subject; or ii) on a medium and then placing the medium on the skin surface of the subject. The method further includes applying light in the visible spectrum for a predetermined amount of time to the placed quantity of hybridized fluorescent silk, wherein the hybridized fluorescent silk is one of KillerRed, SuperNova, KillerOrange, Dronpa, TurboGFP, mCherry, or any combination thereof.

Abstract: An apparatus and method for treating a substrate are provided. The apparatus includes at least one first process chamber configured to supply a developer onto the substrate; at least one second process chamber configured to treat the substrate using a supercritical fluid; a transfer chamber configured to transfer the substrate from the at least one first process chamber to the at least one second process chamber, while the developer supplied in the at least one first process chamber remains on the substrate; and a temperature and humidity control system configured to manage temperature and humidity of the transfer chamber by supplying a first gas of constant temperature and humidity into the transfer chamber.

Abstract: A display device includes a substrate including a display area and a non-display area, a plurality of pixels disposed in the display area, a common voltage supply wiring overlapping the non-display area and disposed on the substrate, a driving voltage supply wiring overlapping the non-display area and disposed on the substrate, and a data voltage supply wiring overlapping the non-display area and electrically connected to the plurality of pixels, where at least one of the common voltage supply wiring and the driving voltage supply wiring includes a chamfered area, the data voltage supply wiring includes a first data voltage supply wiring, a second data voltage supply wiring, and a third data voltage supply wiring, and the first to third data voltage supply wirings are disposed in different layers.

Abstract: A method of inactivating harmful microorganisms of a filtration medium including pathogenic bacteria and viruses is disclosed which includes placing a predetermined quantity of a hybridized fluorescent silk on to a filtration medium, applying light for a predetermined amount of time to the placed quantity of the hybridized fluorescent silk, and passing a fluid through the medium, wherein the fluid is one of substantially air or substantially water, wherein the hybridized fluorescent silk is one of KillerRed, SuperNova, KillerOrange, Dronpa, TurboGFP, mCherry, or any combination thereof.

Abstract: Disclosed herein are a video decoding method and apparatus and a video encoding method and apparatus. In video encoding and decoding, multiple partition blocks are generated by splitting a target block. A prediction mode is derived for at least a part of the multiple partition blocks, among the multiple partition blocks, and prediction is performed on the multiple partition blocks based on the derived prediction mode. When prediction is performed on the partition blocks, information related to the target block may be used, and information related to an additional partition block, which is predicted prior to the partition block, may be used.

Abstract: The present invention relates to a method for preparing a sulfide-based solid electrolyte, a sulfide-based solid electrolyte prepared by the method, and an all-solid-state lithium secondary battery including the sulfide-based solid electrolyte. The method of the present invention includes a) mixing Li2S with P2S5 to prepare a mixed powder, b) placing the mixed powder, an ether, and stirring balls in a container, sealing the container, followed by stirring to prepare a suspension, and c) stirring the suspension under high-temperature and high-pressure conditions to prepare sulfide-based solid particles.

Abstract: Disclosed is an atmospheric shielding type analysis device for a cross-section of a battery cell and an analysis method using the same. The device comprises 1) a body member comprising a bottom plate, a side wall, and an inner space partitioned by the bottom plate and the side wall; 2) a cover member; 3) a first conductive wire member penetrating one side wall of the body member; 4) a first mounting member comprising a first substrate having a shape of a plate and being coupled to an end of the first conductive wire member; 5) a second conductive wire member penetrating another side wall of the body member; 6) a second mounting member comprising a second substrate having a shape of a plate and being coupled to an end of the second conductive wire member; 7) a gas inlet; and 8) a gas outlet.

Abstract: A current collector for a positive electrode according to the present invention may include a base film, a conductive material provided on at least one of upper and lower surfaces of the base film, a metal piece provided on the upper or lower surface of the base film and electrically connected to the conductive material, and a lead tab joined to any one of the metal piece, the conductive material, and the base film and electrically connected to the conductive material, in which the conductive material is positioned between the metal piece and the base film or between the lead tab and the base film, and in which the lead tab is welded to one of the metal pieces provided on the upper and lower surfaces of the base film or welded to the metal piece provided on one surface of the base film that faces the lead tab.

Abstract: Disclosed are an all-solid-state battery which is provided with an intermediate layer provided on an anode current collector and formed of an alloy including a metal configured to form an alloy with lithium, and a method for manufacturing the same. The all-solid-state battery includes the anode current collector, the intermediate layer located on the anode current collector, a solid electrolyte layer located on the intermediate layer, a cathode active material layer located on the solid electrolyte layer, and a cathode current collector located on the cathode active material layer, and the intermediate layer includes the alloy of a first metal configured to form an alloy with lithium and a second metal configured not to form an alloy with lithium.

Abstract: A current collector for electrodes according to an embodiment of the present disclosure may include a polymer film, and a conductive material provided on at least one surface of upper and lower surfaces of the polymer film, wherein the conductive material may have a function of an electrochemical fuse or a function of blocking a short-circuit current.

Abstract: A photoelectric device is disclosed. The photoelectric device includes a first electrode, a second electrode, and an electrolyte disposed between the first electrode and the second electrode. The second electrode includes a transparent layer for allowing light to penetrate into the second electrode, an electron transport layer coupled to the transparent layer, and a genetically hybridized fluorescent silk layer as a photo-sensitizer coupled to the electron transport layer.

Abstract: Disclosed are an all-solid-state battery having a protective layer including a composite including a metal sulfide and a carbon component, and a method for manufacturing the same. The all-solid-state battery includes an anode current collector, the protective layer disposed on the anode current collector, a solid electrolyte layer disposed on the protective layer, a cathode active material layer disposed on the solid electrolyte layer, and a cathode current collector disposed on the cathode active material layer, and the protective layer includes a matrix comprising the composite including the metal sulfide and the carbon component, and a metal component distributed in the matrix and capable of alloying with lithium.

Abstract: A cathode for an all-solid-state battery includes a conductive material wherein the conductive material includes a carbon-based material and a metal fluoride disposed on the surface of the carbon-based material, and a method of manufacturing the same. The cathode for an all-solid-state battery includes a cathode active material, a solid electrolyte, and a conductive material, wherein the conductive material includes a carbon-based material and a metal fluoride disposed on a surface of the carbon-based material.

Abstract: A modified conjugated diene-based polymer represented by Formula 1, wherein a terminal of a polymer chain is modified, and a method for preparing same are provided. By including a modifier derived unit having a specific structure, a beta value affecting cold flow may be reduced through controlling the degree of branch, and accordingly, the cold flow of a polymer may be efficiently controlled and a mooney viscosity increasing ratio may be improved.