Abstract: The present invention relates to a wearable pressure ulcer detection sensor, and the wearable pressure ulcer detection sensor according to the present invention includes a pressure sensor measuring pressure based on a change in capacitance caused by physical force, a temperature sensor measuring temperature based on a change in electrical conductivity due to electron hopping, and an impedance sensor including two electrodes spaced apart from each other and in contact with skin.

Abstract: The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.

Abstract: The present invention relates to an alkylene-oxide-added polyol composition, a polyurethane using same, and a hot-melt adhesive comprising same, and, more specifically, to an alkylene oxide-added polyol composition, a polyurethane using same, and a hot-melt adhesive comprising same, the composition being prepared by performing, in a specific content ratio, an addition reaction between an alkylene oxide and an anhydrosugar alcohol composition comprising a) a monoanhydrosugar alcohol, b) a dianhydrosugar alcohol, c) a polysaccharide alcohol, d) an anhydrosugar alcohol derived from a polysaccharide alcohol, and e) a polymer of at least one of a) to d), and thus can increase the amount of bio components, improves adhesive strength, and enables a polyurethane to be prepared at a cost lower than that of when using petroleum polyols and other biopolyols.

Abstract: The present invention relates to a composition for forming an environmentally friendly polyurethane foam, the composition having improved storage stability, air permeability, and anti-oxidation characteristics and to a method for manufacturing a polyurethane foam and, more specifically, to an isocyanate pre-polymer prepared by reaction of a polyisocyanate and a polyol component comprising a bio-polyol, to a composition for forming an environmentally friendly polyurethane foam, the composition having improved storage stability, air permeability, and anti-oxidative characteristics by comprising the pre-polymer as one component, to a method for manufacturing a polyurethane foam using the same, and to an environmentally friendly polyurethane foam manufactured thereby.

Abstract: The present invention relates to a polycarbonate composite, a producing method thereof, and a molded article comprising same. More specifically, the present invention relates to: a polycarbonate composite comprising a matrix resin, which is a polycarbonate resin in which an anhydrosugar alcohol is copolymerized, and a nanomaterial dispersed in the matrix resin, wherein the polycarbonate composite exhibits a more remarkably improved tensile modulus and tensile strength than a conventional biopolycarbonate resin composite, by using, as a diol component, a solid dispersion or molten dispersion obtained by introducing a nanomaterial (dispersible substance) into an anhydrosugar alcohol (dispersion medium) in the form of an aqueous dispersion at the time of manufacture, and has uniform physical properties as the nanomaterial is uniformly dispersed in the composite; a producing method thereof; and a molded article comprising same.

Abstract: The present invention relates to ether diol-derived polycarbonate diol of anhydrohexitol, a method for preparing same, polyurethane prepared from same and an adhesive comprising same and, more specifically, to polycarbonate diol, a method for preparing same, polyurethane prepared from same and an adhesive, paint and coating agent comprising same, the polycarbonate diol comprising repeating units derived from: ether diol of anhydrohexitol; carbonic diester; and random anhydrohexitol, and thus exhibiting enhanced color improving effect compared to existing polycarbonate diol and providing notably enhanced adhesion (T-peeling strength or shear strength) to polyurethane prepared by means of same.

Abstract: The present invention relates to a polyol composition comprising anhydrosugar alcohols and an anhydrosugar alcohol polymer and, more specifically, to a polyol composition comprising a monoanhydrosugar alcohol, a dianhydrosugar alcohol, and a polymer of a monoanhydrosugar alcohol and/or a dianhydrosugar alcohol, the polyol composition being usable in various fields since the physical property conditions of the composition, such as number average molecular weight (Mn), polydispersity index (PDI) and hydroxyl value, satisfy specific levels, and, particularly, being capable of remarkably improving the physical properties of a polyurethane, such as tensile strength and elongation, when used as a polyurethane chain extender.

Abstract: Compositions for inhibiting the aggregation of a granin from a non-toxic low molecular weight form to a toxic high molecular weight aggregated form and/or dissociating a high molecular weight aggregated form to a low molecular weight form are provided. Such a composition typically includes one or more active compounds or agents, which may also be referred to herein as disaggregation compounds. Using the compounds and compositions described herein, methods of i) modulating, inhibiting or preventing the interaction of granins with metal ions, ii) modulating, inhibiting, preventing the aggregation of granins or dissociating aggregated granins, iii) reducing or inhibiting cell toxicity, iv) treating or preventing dementia or Alzheimer's disease, and v) preventing or treating Parkinson's and/or Huntington's diseases are also provided.

Abstract: The present invention relates to a diisocynate compound having anhydrosugar alcohol core and a preparation method therefor and, more specifically, to a diisocynate compound having anhydrosugar alcohol core and a preparation method therefor, wherein the diisocynate compound is prepared through a reaction with a nitrile compound, a hydrogenation reaction, and an end-group substitution reaction while a recyclable, plant-based anhydrosugar alcohol or anhydrosugar alcohol-alkylene glycol is used as a raw material, and the diisocynate compound can be utilized in various fields, such as soft or hard polyurethane expanded foams, molded foams, coating, adhesives or glues, fibers, and polymer synthesis.

Abstract: The present invention relates to a solid dispersion, a preparation method therefor, a chain-extended polyurethane using same, and an epoxy resin composition comprising same and, more particularly, to a solid dispersion in which an inorganic or organic material-derived isotropic or anisotropic substance is used as a dispersoid and dispersed at room temperature in a solid-phase dispersion medium such as polyols and sugars, whereby the dispersion can be easily stored and used, reduce transportation cost, prevent or alleviate the aggregation or precipitation caused during the storage of products, with the results of working efficiency improvement and processing cost reduction, and, when applied to polyurethane, can increase strength and provide an improved strength, compared to conventional curing agent, a preparation method therefor, a chain-extended polyurethane using same, and an epoxy resin composition comprising same.

Abstract: The present invention relates to a composition for forming an environmentally friendly polyurethane foam, the composition having improved storage stability, air permeability, and anti-oxidation characteristics and to a method for manufacturing a polyurethane foam and, more specifically, to an isocyanate pre-polymer prepared by reaction of a polyisocyanate and a polyol component comprising a bio-polyol, to a composition for forming an environmentally friendly polyurethane foam, the composition having improved storage stability, air permeability, and anti-oxidative characteristics by comprising the pre-polymer as one component, to a method for manufacturing a polyurethane foam using the same, and to an environmentally friendly polyurethane foam manufactured thereby.

Abstract: The present invention relates to an anhydrosugar alcohol composition having enhanced storage stability, and an anhydrosugar alcohol storage method, and more specifically, to an anhydrosugar alcohol composition having enhanced storage stability by comprising anhydrosugar alcohol and an amine-based additive; and to a method by which anhydrosugar alcohol having excellent quality may be provided by having the storing of the anhydrosugar alcohol performed under the existence of the amine-based additive, thereby remarkably enhancing the storage stability of the anhydrosugar alcohol.

Abstract: Compositions for inhibiting the aggregation of a granin from a non-toxic low molecular weight form to a toxic high molecular weight aggregated form and/or dissociating a high molecular weight aggregated form to a low molecular weight form are provided. Such a composition typically includes one or more active compounds or agents, which may also be referred to herein as disaggregation compounds. Using the compounds and compositions described herein, methods of i) modulating, inhibiting or preventing the interaction of granins with metal ions, ii) modulating, inhibiting, preventing the aggregation of granins or dissociating aggregated granins, iii) reducing or inhibiting cell toxicity, iv) treating or preventing dementia or Alzheimer's disease, and v) preventing or treating Parkinson's and/or Huntington's diseases are also provided.

Abstract: The present invention relates to an anhydrosugar alcohol composition having enhanced storage stability, and an anhydrosugar alcohol storage method, and more specifically, to an anhydrosugar alcohol composition having enhanced storage stability by comprising anhydrosugar alcohol and an amine-based additive; and to a method by which anhydrosugar alcohol having excellent quality may be provided by having the storing of the anhydrosugar alcohol performed under the existence of the amine-based additive, thereby remarkably enhancing the storage stability of the anhydrosugar alcohol.

Abstract: The present invention relates to a polyester resin comprising a biomass-derived monomer and a preparation method therefor, and a powder paint composition comprising the resin and, more specifically, to a polyester resin and a preparation method therefor, and a powder paint composition comprising the resin, wherein the polyester resin comprises, as a repeat unit, a biomass-derived unit having improved reactivity and being derived from an anhydrosugar alcohol or a derivative thereof, thereby solving the problem of the depletion of petroleum resources corresponding to limited resources, exhibiting eco-friendliness and high-heat resistance, and remarkably improving weather resistance and flexibility of a coating film when used for a powder paint.

Abstract: The present invention relates to functional polyurethane which can be widely used in preparation of foams, elastomers, adhesives, coating materials, sealants, etc., and its preparation method and use.

Abstract: The present invention relates to a method for screening a cancer therapeutic agent, comprising the steps of: (a) contacting a test substance of interest with a cell containing a granulogenic factor-encoding nucleotide sequence; and (b) analyzing expression of the granulogenic factor or production of secretory granules, wherein the test substance is determined as the cancer therapeutic agent where it inhibits the expression of the granulogenic factor or the production of secretory granules. In the present invention, the expression of the granulogenic factor contributes to induction of secretory granule formation in non-secretory cells, and inhibition of the granulogenic factor expression leads to inhibition of secretory granule formation in secretory cells.