Abstract: The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: wherein X, Z, R1 and R2 are as defined in the specification. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Abstract: A glass composition, a glass article prepared therefrom, and a display device are provided. The a glass article includes, as a glass composition, 62 to 72 mol % of SiO2, greater than 0 and equal to or less than 10 mol % of Al2O3, 10 to 20 mol % of Na2O, greater than 0 and equal to or less than 5 mol % of K2O, 7 to 18 mol % of a sum of CaO and MgO with respect to a total weight of the glass article, satisfying Relation 1 below, and having a thickness of 100 ?m or less: 0.1?Al2O3/(sum of Na2O and K2O)?0.6 . . . (Relation 1), where Al2O3, Na2O and K2O are contents of corresponding components measured in mole percents (mol %).

Abstract: Various embodiments of the present invention relate to a secondary battery, and the objective of the present invention is to provide a secondary battery, which has drop-impact resistance, by providing an electrode assembly having a relatively thick inner circumferential and a relatively thin outer circumferential tab. To this end, disclosed is a secondary battery, which comprises an electrode assembly comprising: an anode plate having an inner circumferential tab formed at a wound front end thereof; a separator covering the anode plate; and a cathode plate having an outer circumferential tab formed at a wound distal end thereof.

Abstract: A glass article has a thickness in a range of 20 ?m to 100 ?m and a third elastic energy index of 1.8 MPa2/m0.5 or greater, where the third elastic energy index is defined by Equation 2-3: Third elastic energy index (Eelas3)=GIC×(1/B)×Eabs (Equation 2-3), where GIC is a fracture energy index defined by Equation 1: Fracture energy index (GIC)=(KIC2×(1?v2))/E (Equation 1), where KIC is fracture toughness, v is Poisson's ratio, and E is Young's modulus, B is brittleness (fracture toughness KIC/hardness Hv), and Eabs is absorption energy defined by Equation A: Absorption energy (Eabs)=?2×(1?v)/E (Equation A), where ? is surface strength defined by Equation B: Surface strength (?)=(E×?×?2)/(1?v) (Equation B), where E is Young's modulus, ? is a thermal expansion coefficient, ? is density, and v is Poisson's ratio.

Abstract: A glass composition, a glass article prepared therefrom, and a display device are provided. The glass article includes as a glass composition: 59 to 69 mol % of SiO2, 8 to 18 mol % of Al2O3, greater than 0 to 5 mol % of Na2O, greater than 0 to 5 mol % of ZnO, and greater than 0 to 10 mol % of B2O3, and glass article further includes 10 to 20 mol % of CaO or 15 to 25 mol % of MgO, satisfies Relation 1 below, and has a thickness of 100 ?m or less, 4.5?Al2O3/Na2O?5.5??(Relation 1), where, in Relation 1, Al2O3 and Na2O represent contents (mol %) of corresponding components, respectively, in the glass composition.

Abstract: The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: wherein X, Z, R1 and R2 are as defined in the specification. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Abstract: To improve the precision of a dental restoration, the present invention provides a dental restoration manufacturing method comprising: a first step of preparing a general-purpose wax bite which is formed of paraffin wax, and which is formed to be standardized in correspondence to a preset standard dental arch profile and is arranged between a part in which implantation is to be performed and an opposite corresponding part, and which comprises a variable matching part corresponding to the part in which implantation is to be performed and being softened when heated to the temperature greater than or equal to a preset temperature, and a press protrusion part that is formed integrally with the variable matching part and protrudes to correspond to the opposite corresponding part and that is softened when heated to the temperature greater than or equal to a preset temperature; a second step of respectively acquiring, through an image capture device, a plurality of scanning images of the part in which implantation i

Abstract: In order to improve manufacturing convenience and precision, the present invention provides a digital denture manufacturing method comprising: a first step of acquiring a three-dimensional work image, on which occlusion information between a target dental arch and an opposing dental arch and implant information of a fixture implanted in the target dental arch are displayed, and preparing a temporary denture in which a binding region formed to correspond to a binding portion profile of an abutment fastened to the fixture is arrayed and arranged; a second step of acquiring an auxiliary scan image for the temporary denture; a third step of acquiring, from the auxiliary scan image, a correction surface image on three-dimensional surface information of an inner surface-side engagement groove of the temporary denture including the binding region; and a fourth step of designing and manufacturing a digital denture having a virtual binding groove corresponding to the position and the shape of the three-dimensional sur

Abstract: The present invention provides a digital dental prosthesis manufacturing method including a first step in which a three-dimensional work image is acquired, the three-dimensional work image including surface information on an inner side of an oral cavity and a target dental arch in which fixtures are placed and occlusion information between the target dental arch and an opposing dental arch; a second step in which a temporary digital dental prosthesis is designed and manufactured; a third step in which the manufactured temporary digital dental prosthesis is installed on the target dental arch; and a fourth step in which a virtual coupling groove, which corresponds to surface information on the corrected coupling region, is set in an inner surface profile, which is set according to surface information on the corrected temporary shape-matching surface that is included in the corrected scan image, and a final digital dental prosthesis is designed and manufactured.

Abstract: The present invention provides a dental restoration manufacturing method for improving the precision and reliability of a dental restoration, the dental restoration manufacturing method comprising: a first step for acquiring, through an imaging device, each of a scanning image of a part where implantation is to take place and a corresponding antagonistic part, before the mounting of a coupling bite disposed between the part where implantation is to take place and the corresponding antagonistic part, and after the mounting of the inner and outer surface portions of the coupling bite in consideration of a vertical dimension of a patient by occlusal pressure, a CT image of the oral cavity occluded by means of the coupling bite, and a gothic arch motion image of a three-dimensional motion trajectory of the temporomandibular joint of the patient in a state where a mastication protrusion part, provided on the coupling bite, and the corresponding antagonistic part are mutually occluded, and transmitting the images t

Abstract: To accurately acquire an image of an inside of an oral cavity of a person to be treated, there is provided a dental retractor including a retracting base portion that includes an inner retracting portion extending in an arch-shaped profile to surround an inner portion of gum at any one side of an upper jaw and a lower jaw inside an oral cavity and having a pressing holding portion formed at an outer peripheral surface so that a tongue is accommodated therein and an outer retracting portion integrally extending from both ends of the inner retracting portion and extending in an arch-shaped profile to surround an outer portion of the gum, and a handle portion including a grip portion connected outward from the retracting base portion.

Abstract: To accurately acquire an image of an inside of an oral cavity of a person to be treated, there is provided a dental retractor including a retracting base portion that includes an inner retracting portion extending in an arch-shaped profile to surround an inner portion of gum at any one side of an upper jaw and a lower jaw inside an oral cavity and having a pressing holding portion formed at an outer peripheral surface so that a tongue is accommodated therein and an outer retracting portion integrally extending from both ends of the inner retracting portion and extending in an arch-shaped profile to surround an outer portion of the gum, and a handle portion including a grip portion connected outward from the retracting base portion.

Abstract: Provided is a method for manufacturing a surgical guide, and a crown and an abutment in a mouth for a dental implant, including an operation of obtaining a primarily scanned image through scanning of inner and outer surfaces of a denture which has a first image matching groove matched with a patient's tooth implanting portion and in which a plurality of reference markers are attached to an outside, obtaining a secondarily scanned image through oral scanning of upper and lower jaws while the denture is installed, preliminarily matching the secondarily scanned image with the primarily scanned image, obtaining an integrated scanned image considering a vertical dimension by reversing the first image matching groove so that an image of the first image matching groove is dimensionalized from the primarily scanned image, and obtaining a CT image through CT scanning of the upper and lower jaws.

Abstract: Disclosed is a dental implant insertion set including a crown; a fixture which has a hex hole formed therein and of which an insertion angle is set so that the hex hole is aligned corresponding to an arrangement angle of the crown; a guide stent including a stent body formed with a profile set through the three-dimensional procedure guide image to be fixed while covering the periodontal tissue; and an abutment having a hex protrusion formed at a lower portion thereof to be matched with and fixed into the hex hole, such that the crown is aligned and fixed.

Abstract: Provided is a method for manufacturing a surgical guide, and a crown and an abutment in a mouth for a dental implant, including an operation of obtaining a primarily scanned image through scanning of inner and outer surfaces of a denture which has a first image matching groove matched with a patient's tooth implanting portion and in which a plurality of reference markers are attached to an outside, obtaining a secondarily scanned image through oral scanning of upper and lower jaws while the denture is installed, preliminarily matching the secondarily scanned image with the primarily scanned image, obtaining an integrated scanned image considering a vertical dimension by reversing the first image matching groove so that an image of the first image matching groove is dimensionalized from the primarily scanned image, and obtaining a CT image through CT scanning of the upper and lower jaws.

Abstract: Disclosed is a dental implant insertion set including a crown; a fixture which has a hex hole formed therein and of which an insertion angle is set so that the hex hole is aligned corresponding to an arrangement angle of the crown; a guide stent including a stent body formed with a profile set through the three-dimensional procedure guide image to be fixed while covering the periodontal tissue; and an abutment having a hex protrusion formed at a lower portion thereof to be matched with and fixed into the hex hole, such that the crown is aligned and fixed.