Abstract: The present invention relates to a composition for preventing, improving, or treating diseases related to advanced glycation end products, comprising an indole derivative or a pharmaceutically acceptable salt thereof. Specifically, the composition of the present invention possesses the effect of trapping methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.

Abstract: The present invention relates to a novel indole derivative and a use thereof. The novel indole derivative according to the present invention traps methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.

Abstract: The present invention relates to a compound represented by Formula 1, a pharmaceutically acceptable salt thereof, or an isomer thereof, and a pharmaceutical composition for treating or preventing proteasome-mediated diseases, comprising the same as an active ingredient.

Abstract: An apparatus of tilting a seat cushion of a vehicle, includes a tilting motor, a pinion gear, a sector gear, and a tilting link which perform the tilting operation of the seat cushion and exert a binding force in a tilted state of the seat cushion and are provided to be connected to both of one side and the other side of a seat cushion frame, and has two sector gears positioned on left and right sides and connected to each other by a connection bar so that, by strengthening a binding force of the front portion of the seat cushion, it is possible to secure the safety of passengers in the event of a collision.

Abstract: Provided is a ceiling storage system capable of correcting a working position and constantly checking stability of a structure by detecting an amount of change in a facility. According to the ceiling storage system, a transport vehicle moves to an upper portion of a first storage area of a plurality of storage areas in a state of gripping an article, and the transport vehicle measures a first distance value between the transport vehicle and the first storage area using a distance sensor and measures a relative position value between the transport vehicle and the first storage area using a vision sensor, before unloading the article from the first storage area.

Abstract: Provided is a ceiling storage system for increasing storage capacity by utilizing a ceiling space inside a fab. The ceiling storage system includes a first overhead rack including a plurality of storage positions for storing a plurality of articles; first and second support rails above the first overhead rack and extending in one direction; a first driving rail above the first overhead rack and in parallel with the first and second support rails; a second driving rail coupled to the first and second support rails and the first driving rail and moving along the first and second support rails and the first driving rail; and a first transport vehicle including a carriage coupled to the second driving rail and moving along the second driving rail, and a hoist and a hand unit installed on the carriage and for loading and unloading the articles to and from the first overhead rack.

Abstract: A loader device includes a frame, a first opening formed in a first side surface of the frame, a second opening formed on a second side surface of the frame, a cavity that connects the first opening and the second opening, a transport unit in the cavity, a first sensor that senses a presence or absence of a first substrate carrier, a second sensor that senses access of a person, and a controller that receives a first sensor signal from the first sensor and receives a second sensor signal from the second sensor. In response to the first sensor signal, the controller controls the transport unit to not transfer a second substrate carrier to the first opening, controls the transport unit to pick up the first substrate carrier from the first opening, and interrupts operation of the transport unit in response to the second sensor signal.

Abstract: The present invention discloses a steerable guidewire and a method for manufacturing the same, and a steerable catheter and a method for manufacturing the same. According to an aspect of the present invention, a steerable guidewire, which is inserted into a catheter and guides the catheter to a desired blood vessel, may include: a steerable tip part that can be bent in at least two stages due to a stimulus from the outside and that is steered in a predetermined direction; and a non-steerable tip part that is not steerable. The steerable tip part may include: a first steerable tip part having a first length and bent in a first angle with respect to the non-steerable tip part; and a second steerable tip part having one end connected to the first steerable tip part, having a second length, and bent and steered into a second angle with respect to the non-steerable tip part. The first steerable tip part may be positioned farther from the non-steerable tip part than the second steerable tip part.

Abstract: Provided is a waste heat recovery power generation system, including: a compressor configured to compress a working fluid; a heat exchanger configured to recover waste heat from waste heat gas supplied from a waste heat source, the recovered waste heat heating the working fluid; a turbine configured to be driven by the working fluid heated by the recovered waste heat; and a recuperator configured to exchange heat between an output fluid of the turbine and an output fluid of the compressor to cool the output fluid of the turbine in which the output fluid of the compressor is branched into a first output fluid and a second output fluid of the compressor.

Abstract: The present invention discloses a steerable guidewire and a method for manufacturing the same, and a steerable catheter and a method for manufacturing the same. According to an aspect of the present invention, a steerable guidewire, which is inserted into a catheter and guides the catheter to a desired blood vessel, may include: a steerable tip part that can be bent in at least two stages due to a stimulus from the outside and that is steered in a predetermined direction; and a non-steerable tip part that is not steerable. The steerable tip part may include: a first steerable tip part having a first length and bent in a first angle with respect to the non-steerable tip part; and a second steerable tip part having one end connected to the first steerable tip part, having a second length, and bent and steered into a second angle with respect to the non-steerable tip part. The first steerable tip part may be positioned farther from the non-steerable tip part than the second steerable tip part.

Abstract: The present invention relates to a supercritical CO2 power generation system of a series recuperative type. According to an embodiment of the present invention, an inlet temperature of a turbine can be increased to increase a work of the turbine, thereby realizing a cycle design having improved turbine efficiency. Further, the number and diameter of pipes connected to a heat exchanger using an external heat source can be reduced to reduce the plumbing related costs, thereby improving economical efficiency.

Abstract: A device for controlling a supply of a working fluid to a power generation cycle with a compressor compressing the working fluid and a precooler cooling the working fluid supplied to the compressor comprises a storage tank storing the working fluid supplied to the power generation cycle and a flotation tank disposed between the precooler and the compressor to flow or temporarily store the working fluid, wherein a pressure within the flotation tank and a flow rate of the working fluid are controlled based on pressures at an inlet of the compressor and an outlet of the precooler.

Abstract: A supercritical CO2 generation system for a parallel recuperative type capable of improving generation efficiency and saving costs is disclosed. According to the supercritical CO2 generation system according to the exemplary embodiment, a compression ratio of a turbine can be increased by arranging recuperators in parallel, thereby maximizing work of the turbine.

Abstract: The present invention relates to a direction-controllable drug injection catheter. According to the present invention, provided is the catheter extending along a central axis “A” including a drug injection part in which a drug injection channel has been formed; a channel opening and closing means which opens and closes the drug injection channel; and a steering structure which is rotationally asymmetric with respect to the central axis “A” and varies according to a pressure change of the drug injection channel for the purpose of steering.

Abstract: The present invention relates to a complex supercritical CO2 generation system capable of increasing the heat exchange efficiency to improve a system output. According to the present invention, a complex generation system of a bottoming cycle and a topping cycle is configured, a flow rate of a cold side outlet of a bottoming cycle recuperators provided in parallel is branched to be supplied to a recuperator of a topping cycle provided in series, thereby increasing heat exchange efficiency of the topping cycle.

Abstract: A CO2 power generation system includes a furnace to burn fuel, a turbine operated by a working fluid supplied thereto, the working fluid being heated by heat generated in the furnace, a recuperator exchanging heat with the working fluid passing through the turbine, a cooler to cool the working fluid passing through the recuperator, and a compressor to compress the working fluid passing through the cooler, wherein the working fluid passing through the compressor is circulated to the furnace, and the working fluid is supercritical CO2.

Abstract: A device for controlling a supply of a working fluid to a power generation cycle with a compressor compressing the working fluid and a precooler cooling the working fluid supplied to the compressor comprises a storage tank storing the working fluid supplied to the power generation cycle and a flotation tank disposed between the precooler and the compressor to flow or temporarily store the working fluid, wherein a pressure within the flotation tank and a flow rate of the working fluid are controlled based on pressures at an inlet of the compressor and an outlet of the precooler.

Abstract: The present invention relates to a complex supercritical CO2 generation system capable of increasing the heat exchange efficiency to improve a system output. According to the present invention, a complex generation system of a bottoming cycle and a topping cycle is configured, a flow rate of a cold side outlet of a bottoming cycle recuperators provided in parallel is branched to be supplied to a recuperator of a topping cycle provided in series, thereby increasing heat exchange efficiency of the topping cycle.

Abstract: The present invention relates to a supercritical CO2 power generation system of a series recuperative type. According to an embodiment of the present invention, an inlet temperature of a turbine can be increased to increase a work of the turbine, thereby realizing a cycle design having improved turbine efficiency. Further, the number and diameter of pipes connected to a heat exchanger using an external heat source can be reduced to reduce the plumbing related costs, thereby improving economical efficiency.

Abstract: A supercritical CO2 generation system for a parallel recuperative type capable of improving generation efficiency and saving costs is disclosed. According to the supercritical CO2 generation system according to the exemplary embodiment, a compression ratio of a turbine can be increased by arranging recuperators in parallel, thereby maximizing work of the turbine.