Patents by Inventor Seunghyon Choe

Seunghyon Choe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ACTIVIN/BMP7 CHIMERAS: SUPER-ACTIVE SAB704 AND SAB715, AND THEIR RESPECTIVE NOGGINSENSITIZED VARIANTS, NAB704 AND NAB715; AND NAB204
    Publication number: 20210395322
    Abstract: The present disclosure relates to chimeric polypeptide having TGF-beta activity, nucleic acids encoding the polypeptides, and host cells for producing the polypeptides with improved or novel biological and therapeutic properties.
    Type: Application
    Filed: November 13, 2019
    Publication date: December 23, 2021
    Inventors: Seunghyon CHOE, So-Mi YOON
  • Diphtheria toxin vaccines bearing a mutated R domain
    Patent number: 5917017
    Abstract: Diphtheria toxin polypeptides comprising a mutant R binding domain exhibit reduced target cell binding and may be used as vaccines to immunize a mammal against infection by Corynebacterium diphtheria.
    Type: Grant
    Filed: June 8, 1994
    Date of Patent: June 29, 1999
    Assignees: President and Fellows of Harvard College, The Regents of the University of California
    Inventors: R. John Collier, Wei Hai Shen, David Eisenberg, Seunghyon Choe
  • Diphtheria toxin receptor-binding region
    Patent number: 5843711
    Abstract: The invention features a polypeptide consisting of amino acids 379-535 of diphtheria toxin, and portions thereof. This region, shown by X-ray crystallographic analysis to comprise the receptor binding domain of diphtheria toxin, is used as an immunogen and clinical therapeutic against diphtheria.
    Type: Grant
    Filed: November 2, 1995
    Date of Patent: December 1, 1998
    Assignees: The Regents of the University of California, The President and Fellows of Harvard College
    Inventors: R. John Collier, David Eisenberg, Haian Fu, Seunghyon Choe