Abstract: The present invention provides a bi-directional perfusion cannula for use in peripheral veno-arterial extracorporeal membrane oxygenation of a patient, the cannula comprising a cannula main body having a primary lumen, the primary lumen leading to a distal end of the cannula main body for providing retrograde blood perfusion, characterized in that the main body further comprises a passage for passing a second cannula therethrough, the passage being oriented such that when a second cannula is inserted into the passage the second cannula is arranged for providing anterograde blood perfusion.