Patents by Inventor Sevda DELDARI

Sevda DELDARI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FACTORY-ON-A-CHIP FOR PRODUCTION OF BIOLOGICALLY DERIVED MEDICINES/BIOPHARMACEUTICALS/BIOLOGICS/ BIOTHERAPEUTICS
    Publication number: 20230407221
    Abstract: The present invention provides for a fully integrated microfluidic system capable of producing single-dose amounts of biotherapeutics at the point-of-care wherein protein production, purification and product harvest are all integrated as a single microfluidic device which is portable and capable of continuous-flow production of biotherapeutics at the microscale using a cell-free reaction system.
    Type: Application
    Filed: September 11, 2023
    Publication date: December 21, 2023
    Inventors: GOVIND RAO, YORDAN KOSTOV, ABHAY ANDAR, MUSTAFA AL-ADHAMI, SEVDA DELDARI, DOUGLAS D. FREY
  • Factory-on-a-chip for production of biologically derived medicines/biopharmaceuticals/biologics/biotherapeutics
    Patent number: 11708553
    Abstract: The present invention provides for a fully integrated microfluidic system capable of producing single-dose amounts of biotherapeutics at the point-of-care wherein protein production, purification and product harvest are all integrated as a single microfluidic device which is portable and capable of continuous-flow production of biotherapeutics at the microscale using a cell-free reaction system.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: July 25, 2023
    Assignee: University of Maryland, Baltimore County
    Inventors: Govind Rao, Yordan Kostov, Abhay Andar, Mustafa Al-Adhami, Sevda Deldari, Douglas D. Frey
  • METHODS OF ISOLATING A PROTEIN
    Publication number: 20220135619
    Abstract: The disclosure provides a method of separating a protein product, e.g., from a contaminant in a mixture, comprising contacting the mixture with a polishing chromatography matrix. In some embodiments, the polishing chromatography matrix is used together with a retained gradient. In certain embodiments, the retained gradient comprises a pH gradient. In certain embodiments, the mixture comprises a monoclonal antibody product of a prior protein A chromatography.
    Type: Application
    Filed: February 24, 2020
    Publication date: May 5, 2022
    Applicant: Bristol-Myers Squibb Company
    Inventors: Douglas D. FREY, Yang LIU, Sevda DELDARI, Ryan Keith SWANSON, Chittoor R. NARAHARI, Ronald Charles BATES, Sanchayita GHOSE, Zhengjian LI