Abstract: Systems and methods for performing a multi-test-period titration for oral appliance therapy are described herein. A system includes a mandibular displacement device configured to be positioned in an oral cavity of a subject, a monitoring unit configured to sense one or more physiological inputs from the subject; and a control unit. The system is configured to configure at least one of the mandibular displacement device or the monitoring unit during the diagnostic sleep test protocol, perform the diagnostic sleep test protocol, configure at least one of the mandibular displacement device or the monitoring unit during the titration for oral appliance therapy protocol, and perform the titration for oral appliance therapy protocol.

Abstract: Systems and methods for setting one or more parameters for a multi-test-period titration for oral appliance therapy are described herein. A method can include performing a titration for oral appliance therapy during a first test period, identifying a variable associated with the titration performed during the first test period, and setting a parameter for a titration for oral appliance therapy to be performed during a second test period. The parameter can be dependent on the variable associated with the titration performed during the first test period. The method can also include performing the titration for oral appliance therapy during the second test period, and establishing an outcome of oral appliance therapy based on the titrations performed during the first and second test periods.

Abstract: An example method for detecting respiratory disturbances experienced by a subject can include receiving an airflow signal and at least one of an acoustic or vibration signal, where the airflow, acoustic, and/or vibration signals are associated with the subject's breathing. At least one feature can be extracted from the airflow signal and at least one feature can be extracted from at least one of the acoustic or vibration signal. Based on the extracted features, at least one respiratory disturbance can be detected. The respiratory disturbance can be flow limited breath or inspiratory flow limitation (“IFL”).

Abstract: An example method for detecting respiratory disturbances experienced by a subject can include receiving an airflow signal and at least one of an acoustic or vibration signal, where the airflow, acoustic, and/or vibration signals are associated with the subjects breathing. At least one feature can be extracted from the airflow signal and at least one feature can be extracted from at least one of the acoustic or vibration signal. Based on the extracted features, at least one respiratory disturbance can be detected. The respiratory disturbance can be flow limited breath or inspiratory flow limitation (“IFL”).

Abstract: Systems and methods for setting one or more parameters for a multi-test-period titration for oral appliance therapy are described herein. A method can include performing a titration for oral appliance therapy during a first test period, identifying a variable associated with the titration performed during the first test period, and setting a parameter for a titration for oral appliance therapy to be performed during a second test period. The parameter can be dependent on the variable associated with the titration performed during the first test period. The method can also include performing the titration for oral appliance therapy during the second test period, and establishing an outcome of oral appliance therapy based on the titrations performed during the first and second test periods.

Abstract: An example method for detecting respiratory disturbances experienced by a subject can include receiving an airflow signal and at least one of an acoustic or vibration signal, where the airflow, acoustic, and/or vibration signals are associated with the subjects breathing. At least one feature can be extracted from the airflow signal and at least one feature can be extracted from at least one of the acoustic or vibration signal. Based on the extracted features, at least one respiratory disturbance can be detected. The respiratory disturbance can be flow limited breath or inspiratory flow limitation (“IFL”).