Patents by Inventor Seyed Mahdi Rezayat

Seyed Mahdi Rezayat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240082156
    Abstract: A method for producing liposomes entrapping Cyclosporine A (CsA). The method comprising preparing a suspension of CsA-free liposomes with a pH level of 7, preparing a mixture with a pH level of 7 by adding the suspension of CsA-free liposomes in the sucrose phosphate buffer to an ethanolic solution of CsA, and forming the liposomes entrapping CsA by incubating the mixture at a temperature level between 42° C. and 48° C. for a time duration between 55 and 65 minutes.
    Type: Application
    Filed: November 15, 2023
    Publication date: March 14, 2024
    Inventors: Mahmoud Reza Jaafari, Seyed Ali Nazeri, Seyed Mahdi Rezayat, Ali Reza Partoazar
  • Patent number: 10485895
    Abstract: A mixture for an injectable scaffold may include a self-assembling core and an additive. The additive may include an angiogenic agent, a small molecule drug, and/or an anti-inflammatory agent. The scaffold can be applied to sites where bone growth is desired.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: November 26, 2019
    Assignees: CELLULAR AND MOLECULAR RESEARCH CENTER, IRAN UNIVERSITY OF MEDICAL SCIENCES
    Inventors: Shima Tavakol, Behnaz Tavakol, Amin Almasi, Seyed Mahdi Rezayat Sorkhabadi
  • Patent number: 10428111
    Abstract: A molecule comprising a lipid, a peptide and a linker to bind the lipid to the peptide which have specific amino acid sequence to bind to Epidermal Growth Factor Receptor (EGFR) of tumor cells, and a liposomal composition which is targeted by the molecule, and method for preparing thereof is disclosed.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: October 1, 2019
    Inventors: Mahmoud Reza Jaafari, Masoumeh Zahmatkeshan, Seyed Mahdi Rezayat Sorkhabadi
  • Patent number: 10123973
    Abstract: Disclosed is a liposomal composition for treatment of cancer, which includes at least one PEG-Phospholipid conjugated molecule, cholesterol, and at least one phospholipid.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: November 13, 2018
    Assignees: MASHHAD UNIVERSITY OF MEDICAL SCIENCE, TEHRAN UNIVERSITY OF MEDICAL SCIENCE
    Inventors: Mahmoud Reza Jaafari, Fatemeh Gheybi, Seyed Mahdi Rezayat Sorkhabadi
  • Patent number: 9855216
    Abstract: A liposomal composition includes at least two anti-tumor herbal drugs that are simultaneously co-encapsulated. Optionally, the liposomal composition is targeted by adding a monoclonal antibody is added to the liposomes.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: January 2, 2018
    Assignees: UNIVERSITY OF TEHRAN
    Inventors: Ghasem Amoabediny, Mohammad Mahdi Ochi, Seyed Mahdi Rezayat, Azim Akbarzadeh, Bahman Ebrahimi
  • Publication number: 20170290951
    Abstract: A mixture for an injectable scaffold may include a self-assembling core and an additive. The additive may include an angiogenic agent, a small molecule drug, and/or an anti-inflammatory agent. The scaffold can be applied to sites where bone growth is desired.
    Type: Application
    Filed: June 26, 2017
    Publication date: October 12, 2017
    Inventors: Shima Tavakol, Behnaz Tavakol, Amin Almasi, Seyed Mahdi Rezayat Sorkhabadi
  • Publication number: 20170183380
    Abstract: A molecule comprising a lipid, a peptide and a linker to bind the lipid to the peptide which have specific amino acid sequence to bind to Epidermal Growth Factor Receptor (EGFR) of tumor cells, and a liposomal composition which is targeted by the molecule, and method for preparing thereof is disclosed.
    Type: Application
    Filed: July 28, 2016
    Publication date: June 29, 2017
    Inventors: Mahmoud Reza Jaafari, Masoumeh Zahmatkeshan, Seyed Mahdi Rezayat Sorkhabadi
  • Publication number: 20170172921
    Abstract: A method for preparing a liposome composition for delivering polyphenolic compounds to the target organs may include preparing a complex that contains at least one polyphenolic compound. Then, encapsulating the polyphenolic compound into a liposome composition by admixing the prepared complex with the liposome ingredients.
    Type: Application
    Filed: December 14, 2016
    Publication date: June 22, 2017
    Inventors: Mahmoud Reza Jaafari, Fatemeh Gheybi, Seyed Mahdi Rezayat Sorkhabadi
  • Publication number: 20160228362
    Abstract: A liposomal composition includes at least two anti-tumor herbal drugs that are simultaneously co-encapsulated. Optionally, the liposomal composition is targeted by adding a monoclonal antibody is added to the liposomes.
    Type: Application
    Filed: April 15, 2016
    Publication date: August 11, 2016
    Inventors: Ghasem Amoabediny, Mohammad Mahdi Ochi, Seyed Mahdi Rezayat, Azim Akbarzadeh, Bahman Ebrahimi
  • Publication number: 20160228365
    Abstract: Disclosed is a liposomal composition for treatment of cancer, which includes at least one PEG-Phospholipid conjugated molecule, cholesterol, and at least one phospholipid.
    Type: Application
    Filed: April 15, 2016
    Publication date: August 11, 2016
    Inventors: Mahmoud Reza Jaafari, Fatemeh Gheybi, Seyed Mahdi Rezayat Sorkhabadi
  • Patent number: 9395362
    Abstract: Modified western blot membranes with silver nanoparticle allow the small peptides of the NS1 protein of the poultry influenza virus to be kept in the membrane and not to diffuse during transferring from the Tricine SDS PAGE. These peptides may differentiate infected from vaccinated poultry.
    Type: Grant
    Filed: October 18, 2010
    Date of Patent: July 19, 2016
    Assignee: NANO JAV DARU COMPANY
    Inventors: Rasool Madani, Seyed Mahdi Rezayat, Saeed Sarkar, Tara Emami
  • Publication number: 20130178603
    Abstract: The various embodiments herein provide a method of synthesizing a multi-mode cancer targeted nanoparticles. The method comprises the steps of preparing a plurality of nanoparticles and covalently conjugating monoclonal antibodies on surface of the prepared plurality of nanoparticles. The plurality of nanoparticles consists of a protein and a drug. The protein is Human Serum Albumin protein (HSA) and the drug is methotrexate. The monoclonal antibodies are anti-MUC1 nanobodies. According to an embodiment herein, a multi-mode cancer targeted nanoparticles comprising a plurality of cross linked nanoparticles of protein and drug molecules and covalently linked molecules of monoclonal antibodies. The molecules of monoclonal antibodies are linked on a surface of the plurality of cross linked nanoparticles.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 11, 2013
    Inventors: Rassoul Dinarvand, Mohammad Ali Derakhshan, Fatemeh Rahbarizadeh, Reza Faridi Majidi, Azade Taheri Borujeni, Seyed Mahdi Rezayat
  • Publication number: 20130017536
    Abstract: Modified western blot membranes with silver nanoparticle allow the small peptides of the NS1 protein of the poultry influenza virus to be kept in the membrane and not to diffuse during transferring from the Tricine SDS PAGE. These peptides may differentiate infected from vaccinated poultry.
    Type: Application
    Filed: October 18, 2010
    Publication date: January 17, 2013
    Applicant: NANO JAV DARU COMPANY
    Inventors: Rasool Madani, Seyed Mahdi Rezayat, Saeed Sarkar, Tara Emami
  • Patent number: 7879996
    Abstract: Provided is a compound and methods for preparation thereof according to formula (I) where A1, A2, A3, and A4 are each a group containing 1 to 40 carbon atoms and at least one carboxylic group, R, R? and R? are each hydrogen or a group containing 1 to 80 carbon atoms, M is bivalent or an element capable of complexing with a pyrrole nitrogen atom, L is a linking group, B is a fullerene, and the compound is soluble in water.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: February 1, 2011
    Inventors: Saeed Sarkar, Seyed Mahdi Rezayat, Anatoly Leonidovich Buchachenko, Dmitry Anatolevich Kuznetsov, Marina Alexeyevna Orlova, Marina Abramovna Yurovskaya, Igor Viktorovich Trushkov
  • Publication number: 20080317876
    Abstract: The present invention describes the use of the magnetic magnesium isotope 25Mg2+ for the manufacture of a medicament for treating hypoxia. Furthermore, the present invention provides a medicament for treating hypoxia comprising the magnetic magnesium isotope 25Mg2+ and a porphylleren compound according to formula (I) wherein the residues A1, A2, A3, and A4 independently are a group containing 1 to 40 carbon atoms and at least one carboxylic group, the residues R, R? and R? independently are hydrogen or a group containing 1 to 80 carbon atoms, M is 2 H or an element capable of complexing with pyrrole nitrogen atom and L is a linking group and B is a fullerene residue.
    Type: Application
    Filed: May 19, 2008
    Publication date: December 25, 2008
    Inventors: Saeed Sarkar, Seyed Mahdi Rezayat, Anatoly Leonidovich Buchachenko, Dmitry Anatolevich Kuznetsov, Marina Alexeyevna Orlova, Marina Abramovna Yurovskaya, Igor Viktorovich Trushkov
  • Publication number: 20080319187
    Abstract: Provides is a porphylleren compound (and methods for preparation thereof) according to formula (I) where the residues A1, A2 A3, and A4 independently are a group containing 1 to 40 carbon atoms and at least one carboxylic group, the residues R, R? and R? independently are hydrogen or a group containing 1 to 80 carbon atoms, M is 2 H or an element capable of complexing with pyrrole nitrogen atom and L is a linking group and B is a fullerene residue.
    Type: Application
    Filed: May 19, 2008
    Publication date: December 25, 2008
    Inventors: Saeed Sarkar, Seyed Mahdi Rezayat, Anatoly Leonidovich Buchachenko, Dmitry Anatolevich Kuznetsov, Marina Alexeyevna Orlova, Marina Abramovna Yurovskaya, Igor Viktorovich Trushkov