Abstract: The present invention relates to compositions for killing undifferentiated epithelial cells during cataract surgery on an eye to prevent posterior capsule clouding after the surgery and to a method for performing cataract surgery on an eye including injecting a cell-killing substance between the anterior capsule and the natural lens prior to removing the natural lens from the eye. The cell-killing substance is preferably an acid or base adjusted aqueous solution having a pH in the range between about 1.0 to below 6.5 or about above 7.5 to 14.0; or a hypotonic solution having a salinity less than 0.9% or a pH adjusted hypotonic solution having a salinity less than 0.9% and a pH either below 6.5 or above 7.5. The compositions of the present invention also incorporates a viscoelastic material, a dye or a mixture thereof, in combination with the cell-killing substance.

Abstract: The present invention relates to devices for killing undifferentiated epithelial cells during cataract surgery on an eye to prevent posterior capsule clouding after the surgery and to a method for performing cataract surgery on an eye including injecting a cell-killing substance between the anterior capsule and the natural lens prior to removing the natural lens from the eye. The cell-killing substance is preferably an acid or base adjusted, aqueous, buffer-containing a solution having a pH in the range between about 1.0 to below 6.5 or about above 7.5 to 14.0 or a buffer-containing hypotonic solution having a salinity less than 0.06%. The devices of the present invention optionally incorporate a viscoelastic material, a dye or a mixture thereof, in combination with the cell-killing substance.

Abstract: The present invention relates to compositions for killing undifferentiated epithelial cells during cataract surgery on an eye to prevent posterior capsule clouding after the surgery and to a method for performing cataract surgery on an eye including injecting a cell-killing substance between the anterior capsule and the natural lens prior to removing the natural lens from the eye. The cell-killing substance is preferably an acid or base adjusted aqueous solution having a pH in the range between about 1.0 to below 6.5 or about above 7.5 to 14.0; or a hypotonic solution having a salinity less than 0.9% or a pH adjusted hypotonic solution having a salinity less than 0.9% and a pH either below 6.5 or above 7.5. The compositions of the present invention also incorporates a viscoelastic material, a dye or a mixture thereof, in combination with the cell-killing substance.

Abstract: An intraocular lens for implant in the anterior chamber has four fixation members extending from a lens body with the lens body having curved, opposed end peripheral edges and curved side peripheral edges, the radius of curvature of the end peripheral edges being less than the radius of curvature of the side peripheral edges and the fixation members extending from the junctions of the end and side peripheral edges and having continuously curved proximal legs, junction portions and distal legs terminating at footplates to be received in the angle of intesection of the cornea and iris such that the fixation members flex along their entire length in response to forces applied to the footplates.

Abstract: A syringe, particularly useful for surgery of the eye, includes first and second tubular members disposed in concentric relation, a chamber having a piston movable therein to define a first chamber portion on one side of the piston communicating with a proximal end of the first tubular member and a second chamber portion on the opposite side of the piston communicating with a proximal end of the second tubular member such that movement of the piston forces fluid, such as a cell-killing substance, from the first chamber portion through the first tubular member and simultaneously creates a suction at the distal end of the second tubular member, for example, evacuate any substance escaping from tissue into which the substance is injected.

Abstract: A method of performing cataract surgery on an eye to prevent posterior capsule clouding after the surgery includes injecting a cell-killing substance between the capsule and the natural lens prior to removing the natural lens from the eye. The cell-killing substance is preferably water having a salinity less than 0.9%, with a preferred salinity range of from 0 to 0.6%. A syringe for injecting the cell-killing substance also aspirates any cell-killing substance escaping from the capsule.

Abstract: An intraocular lens for implant in the eye, particularly in the anterior chamber, includes a lens body and a plurality of positioning members having proximal portions extending from the lens body supporting flexible, resilient curved filaments with the proximal portions having a width greater than the filaments to provide stable positioning in the eye and prevent pupillary capture of the lens body. In another embodiment, an intraocular lens has at least three flexible, resilient, fixation filaments extending from the periphery of a lens body and having continuous curving configurations, the fixation filaments being positioned to prevent pupillary capture of the lens body.

Abstract: An intraocular lens for implant in the eye, particularly in the anterior chamber, includes a lens body and at least three flexible, resilient, fixation filaments extending from the periphery of the lens body and having curved intermediate and distal portions to minimize drainage blockage in the angle of intersection of the cornea and the iris while minimizing the risk of passing of a filament through the pupil and tucking a filament in the iris during insertion of the intraocular lens. The use of at least three fixation filaments reduces twisting or turning of the intraocular lens and produces secure centralization of the intraocular lens with increased stability and reduced chance of inadvertent movement of the intraocular lens in the eye.