Patents by Inventor Sfefan Galuska

Sfefan Galuska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20160040252
    Abstract: The invention is directed to methods, reagents, and kits for the detection of MAPK/ERK pathway mutations in a patient diagnosed for cancer. In one embodiment, the invention comprises a sensitive and selective method to identify mutations to the BRAF, KRAS, and NRAS genes in a single reaction. In another aspect of this embodiment, the invention comprises primers and C probes for the detection of the BRAF, KRAS, and NRAS mutations using a single nucleotide primer extension assay. In another embodiment the invention is used to identify and select patients amenable for treatment with an ERK inhibitor.
    Type: Application
    Filed: April 3, 2014
    Publication date: February 11, 2016
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Ken C.N. Chang, Sfefan Galuska, Matthew J. Marton