Abstract: A fertilizer with stress-resistant and disease-resistant functions and a method for preparing the same are provided. The fertilizer with stress-resistant and disease-resistant functions is prepared from the following raw materials in parts by weight: 20-40 parts of a nitrogen fertilizer, 20-30 parts of a phosphate fertilizer, 15-20 parts of a potassium fertilizer, 1.5-3.5 parts of trace elements, 2-4 parts of potassium fulvate, 5-20 parts of sodium humate, 5-15 parts of a citric acid, 3-6 parts of sodium gluconate, 2-4 parts of chitosan oligosaccharide, 10-15 parts of garden burnet root, 5-10 parts of kadsura pepper stein, and 5-10 parts of argy wormwood leaf. The fertilizer with the stress-resistant and disease-resistant functions disclosed herein can improve the yield of wheat crops, has strong resistance to wheat scab and wheat sharp eyespot, and can also improve the drought resistance of wheat under drought stress.