Patents by Inventor Sha LOU

Sha LOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRIVING APPARATUS AND BLOOD PUMP
    Publication number: 20250381386
    Abstract: Provided are a driving apparatus and a blood pump. A housing assembly of the driving apparatus has a through hole. A rotating shaft has a shaft portion and a ball head portion fixedly connected to one end of the shaft portion. The end of the shaft portion that goes away from the ball head portion rotatably penetrates through the through hole. A first shaft sleeve is mounted on the housing assembly. The first shaft sleeve has an accommodating cavity and a shaft hole. The accommodating cavity fits the ball head portion. The shaft hole and the accommodating cavity communicate. The ball head portion is rotatably arranged inside the accommodating cavity. The shaft portion rotatably penetrates through the shaft hole. The diameter of the shaft hole is smaller than the diameter of the ball head portion, so that the ball head portion is confined to the accommodating cavity.
    Type: Application
    Filed: June 16, 2023
    Publication date: December 18, 2025
    Inventors: Sha LOU, Shunzhou YU
  • Substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
    Patent number: 11827597
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: November 28, 2023
    Assignee: INNATE TUMOR IMMUNITY, INC.
    Inventors: Sha Lou, Adrian Ortiz, Christopher Robert Jamison, Eric M. Simmons
  • SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20230097144
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Application
    Filed: November 22, 2022
    Publication date: March 30, 2023
    Inventors: Sha Lou, Adrian Ortiz, Christopher Robert Jamison, Eric M. Simmons
  • Substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
    Patent number: 11572360
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: February 7, 2023
    Assignee: INNATE TUMOR IMMUNITY, INC.
    Inventors: Sha Lou, Adrian Ortiz, Christopher Robert Jamison, Victor W. Rosso, Mansi S. Shah
  • SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20210332040
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Application
    Filed: August 15, 2019
    Publication date: October 28, 2021
    Inventors: Sha Lou, Adrian Ortiz, Rebecca A. Green, Christopher Robert Jamison, Candice Lee Joe, Sergei Kolotuchin, Eric M. Simmons, Neil A. Strotman, Matthew W. Haley, Yichen Tan, Andrew William Glace, Dong Lin, Albert J. DelMonte, Peng Geng, Bahar Inankur, Victor W. Rosso, Mansi S. Shah
  • Antibody-drug conjugate with a tubulysin analog warhead having a stabilized acetate group in the TUV subunit
    Patent number: 11020490
    Abstract: In antibody-drug conjugates having tubulysin analog as the warhead, according to formula (III) the acetate group in the Tuv subunit (dotted box) demonstrates improved stability against hydrolytic cleavage.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: June 1, 2021
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ian S. Young, Sha Lou, Sanjeev Gangwar
  • ANTIBODY-DRUG CONJUGATE WITH A TUBULYSIN ANALOG WARHEAD HAVING A STABILIZED ACETATE GROUP IN THE TUV SUBUNIT
    Publication number: 20190388553
    Abstract: In antibody-drug conjugates having tubulysin analog as the warhead, according to formula (III) the acetate group in the Tuv subunit (dotted box) demonstrates improved stability against hydrolytic cleavage.
    Type: Application
    Filed: June 11, 2019
    Publication date: December 26, 2019
    Inventors: Ian S. Young, Sha Lou, Sanjeev Gangwar
  • Hepatitis C virus inhibitors
    Patent number: 10494400
    Abstract: The present disclosure relates to methods for making asunaprevir, useful treatment of Hepatitis C virus (HCV) infection, and its intermediates.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: December 3, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Scott A. Savage, Nathan R. Domagalski, Brendan Mack, Purushotham Vemishetti, Yuping Qiu, Michael Fenster, Daniel M. Hallow, Glenn Ferreira, Amanda Rogers, Sha Lou, Lindsay Hobson
  • HEPATITIS C VIRUS INHIBITORS
    Publication number: 20180155393
    Abstract: The present disclosure relates to methods for making asunaprevir, useful treatment of Hepatitis C virus (HCV) infection, and its intermediates.
    Type: Application
    Filed: June 23, 2015
    Publication date: June 7, 2018
    Inventors: Scott A. SAVAGE, Nathan R. DOMAGALSKI, Brendan MACK, Purushotham VEMISHETTI, Yuping QIU, Michael FENSTER, Daniel M. HALLOW, Glenn FERREIRA, Amanda ROGERS, Sha LOU, Lindsay HOBSON