Patents by Inventor Shabana Usman Simjee

Shabana Usman Simjee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isoxylitones mediated neurogenesis
    Patent number: 11065211
    Abstract: This invention provides an effective method and a composition for treating neurodegenerative diseases and conditions of the central and peripheral nervous system by stimulating neurogenesis by the use isoxylitones or an isomer, acid analog, a salt or a solvate, thereof.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: July 20, 2021
    Inventors: Atta-ur- Rahman, Muhammad Iqbal Choudhary, Farzana Shaheen, Shabana Usman Simjee, Saba Majeed, Anila Bashir, Kanwal Iftikhar
  • ISOXYLITONES MEDIATED NEUROGENESIS
    Publication number: 20190290598
    Abstract: This invention provides an effective method and a composition for treating neurodegenerative diseases and conditions of the central and peripheral nervous system by stimulating neurogenesis by the use isoxylitones or an isomer, acid analog, a salt or a solvate, thereof.
    Type: Application
    Filed: March 23, 2018
    Publication date: September 26, 2019
    Inventors: Atta-ur- Rahman, Muhammad Iqbal Choudhary, Farzana Shaheen, Shabana Usman Simjee, Saba Majeed, Anila Bashir, Kanwal Iftikhar
  • Modulation of c-FOS and BDNF protein expression in pentylenetetrazole-kindled mice following the treatment with novel anti-epileptic compound HHL-6
    Patent number: 9272998
    Abstract: The present invention evaluated the anti-epileptogenic effect of tryptamine derivative HHL-6 and its effects on the expression of BDNF and c-Fos. HHL-6 possesses potent anticonvulsant and anti-epileptic activity in PTZ-induced acute seizure and chemical kindling model of epilepsy. The results suggests that one of the possible mechanism of HHL-6 to inhibit epileptogenesis might be due to its controlling effect on the cellular and molecular expression of the factors that contribute in the development of epileptogenic plasticity in the CNS.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: March 1, 2016
    Inventors: Shabana Usman Simjee, Sabira Begum, Saima Mahmood Malhi, Huma Jawed, Nadeem Ashraf, Farina Hanif, Bina S. Siddiqui, Farhat Zubair
  • SYNTHESIS AND BIOLOGICAL STUDIES OF AN ISOMERIC MIXTURE OF (E/Z) ISOXYLITONES AND ITS ANALOGUES
    Publication number: 20150148417
    Abstract: The invention relates to an anti-epileptic isoxylitone, 2,2?-(3,5,5-Trimethyl-2-cylohexen-1-ylidene)acetic acid.
    Type: Application
    Filed: January 29, 2015
    Publication date: May 28, 2015
    Inventors: Atta-ur- Rahman, M. Iqbal Choudhary, Farzana Shaheen, Shabana Usman Simjee, Noureen Kahn, Saima Mahmood Malhi, Syed Uzair Ali Shah, Muhammad Nadeem Ashraf
  • PATULETIN A POTENT ANTI-TNF-a AND ANTI-ARTHRITIC COMPOUND FROM TAGETES PATULA
    Publication number: 20150025131
    Abstract: Patuletin, a flavonoid isolated from Tagetes patula, was discovered to be a potent inhibitor of TNF-? production and thus useful in treating diseases related to TNF-? levels in the body.
    Type: Application
    Filed: July 17, 2013
    Publication date: January 22, 2015
    Inventors: Muhammed Ahmed Mesaik, Almas Jabeen, Shaheen Faizi, Shabana Usman Simjee, Samina Bano, Lubna
  • SYNTHESIS AND BIOLOGICAL STUDIES OF AN ISOMERIC MIXTURE OF (E/Z) ISOXYLITONES AND ITS ANALOGUES
    Publication number: 20140221682
    Abstract: The invention relates to an anti-epileptic isoxylitone, 2,2?-(3,5,5-Trimethyl-2-cyclohexen-1-ylidene) acetic acid.
    Type: Application
    Filed: February 4, 2013
    Publication date: August 7, 2014
    Inventors: Atta-ur Rahman, M. Iqbal Choudhary, Farzana Shaheen, Shabana Usman Simjee, Noureen Kahn, Saima Mahmood Malhi, Syed Uzair Ali Shah, Muhammad Nadeem Ashraf
  • Anticonvulsant compounds
    Patent number: 7399888
    Abstract: The invention relates to novel isoxylitones and their use as anticonvulsant and in the treatment of a variety of disorders.
    Type: Grant
    Filed: July 1, 2006
    Date of Patent: July 15, 2008
    Assignee: HEJ Research Institute Karachi University
    Inventors: Attaur Rahman, Mohammad Iqbal Choudhary, Farzana Shaheen, Arun Ganesan, Shabana Usman Simjee, A. Mohsin Raza
  • New Anticonvulsant Compounds
    Publication number: 20080004353
    Abstract: The invention relates to novel isoxylitones and their use as anticonvulsant and in the treatment of a variety of disorders
    Type: Application
    Filed: July 1, 2006
    Publication date: January 3, 2008
    Applicant: HEJ RESEARCH INSTITUTE OF CHEMISTRY
    Inventors: Attaur Rahman, Mohammad Iqbal Choudhary, Farzana Shaheen, A Ganesan, Shabana Usman Simjee, A Mohsin Raza