Patents by Inventor Shaei Huang

Shaei Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of Checkpoint Kinases
    Publication number: 20080004259
    Abstract: The instant invention provides for compounds which comprise substituted indolyl indazoles that inhibit CHK1 activity. The instant compounds provide a novel mechanism of action with unexpected advantageous properties; such unexpected advantageous properties may include increased cellular potency/solubility, greater selectivity, enhanced pharmacokinetic properties, lack of off target activity and so on. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.
    Type: Application
    Filed: February 3, 2006
    Publication date: January 3, 2008
    Inventors: Kenneth Arrington, Mark Fraley, Robert Garbaccio, Shaei Huang, Craig Lindsley, Justin Steen, Feng Yang
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20060178398
    Abstract: The present invention relates to novel LXR ligands of Formula I and pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: September 14, 2005
    Publication date: August 10, 2006
    Inventors: Alan Adams, Shaei Huang, Jason Szewczyk
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20050239769
    Abstract: The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: July 21, 2003
    Publication date: October 27, 2005
    Inventors: A. Jones, Alan Adams, Ahren Green, Shaei Huang, Bruno Tse, Clare Gutteridge, Yuan Cheng
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20050113419
    Abstract: The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: October 26, 2004
    Publication date: May 26, 2005
    Inventors: Shaei Huang, Alan Adams
  • Therapeutic compounds for treating dyslipidemic conditions
    Publication number: 20050014807
    Abstract: Compounds of Formula I and the pharmaceutically acceptable salts and esters thereof, are novel LXR ligands and are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.
    Type: Application
    Filed: November 18, 2002
    Publication date: January 20, 2005
    Inventors: Alan Adams, Shaei Huang, Bruno Tse, A. Brian Jones