Abstract: A computer-implemented method for providing a graphical user interface for use in a virtual reality system. A virtual reality simulation of a user's view of a simulated virtual reality environment is generated and output for display on a virtual reality display, the virtual reality environment comprising the graphical user interface. The graphical user interface comprises one or more selectable cells positioned within the simulated virtual reality environment at one or more corresponding fixed positions within the virtual reality environment relative to a position of the user within the virtual reality environment, the one or more fixed positions being independent of the direction of view of the user.

Abstract: This invention provides new therapeutic potential of nandrolone or a derivative thereof, against protozoal diseases. More specifically, nandrolone or a derivative thereof exhibits anti-protozoal activity against Leishmania major. Anti-protozoal potential of nandrolone derivatives, such as compounds 1-8, can contribute in the development of effective therapies against protozoal diseases, such as leishmaniasis, trypanosomiasis, malaria, toxoplasmosis, babeosis, amoebic dysentery and lambliasis. Another aspect of the invention is a method of testing derivatives of nandrolone for anti-protozoal activity comprising growing Leishmania in the presence of the test derivative and determining the IC50 value.