Patents by Inventor Shafi Kuchay

Shafi Kuchay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Geranylgeranyltransferase I inhibitor for treatment of a PTEN defective cancer
    Patent number: 11583525
    Abstract: A method is disclosed for treating a cancer in a subject that involves administering to the subject a therapeutically affective amount of a geranylgeranyltransferase I (GGTase I) inhibitor, such as GGTI-2418, wherein the cancer comprises a defective PTEN, a hyperactivated FBXL2, or a low level of IP3R3. In some embodiments, the method further involves administering to the subject a therapeutically affective amount of an Akt inhibitor.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: February 21, 2023
    Assignees: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC., NEW YORK UNIVERSITY
    Inventors: Said M. Sebti, Michele Pagano, Shafi Kuchay
  • GERANYLGERANYLTRANSFERASE I INHIBITOR FOR TREATMENT OF A PTEN DEFECTIVE CANCER
    Publication number: 20210093632
    Abstract: A method is disclosed for treating a cancer in a subject that involves administering to the subject a therapeutically affective amount of a geranylgeranyltransferase I (GGTase I) inhibitor, such as GGTI-2418, wherein the cancer comprises a defective PTEN, a hyperactivated FBXL2, or a low level of IP3R3. In some embodiments, the method further involves administering to the subject a therapeutically affective amount of an Akt inhibitor.
    Type: Application
    Filed: June 6, 2018
    Publication date: April 1, 2021
    Inventors: Said M. Sebti, Michele Pagano, Shafi Kuchay