Patents by Inventor Shafique Fidai

Shafique Fidai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-2 SUPERAGONISTS IN COMBINATION WITH ANTI-PD-1 ANTIBODIES
    Publication number: 20230080403
    Abstract: Human interleukin-2 (IL-2) muteins or variants thereof are provided. In particular, provided are IL-2 muteins that have an increased binding capacity for IL-2R? receptor as compared to wild-type IL-2 for use in combination therapies with anti-PD-1 antibodies for the treatment of cancer. Also provided are pharmaceutical compositions that include such anti-PD-1 antibodies and the disclosed IL-2 muteins.
    Type: Application
    Filed: August 2, 2022
    Publication date: March 16, 2023
    Inventors: Fahar Merchant, Shafique Fidai
  • IL-2 superagonists in combination with anti-PD-1 antibodies
    Patent number: 11542312
    Abstract: Human interleukin-2 (IL-2) muteins or variants thereof are provided. In particular, provided are IL-2 muteins that have an increased binding capacity for IL-2R? receptor as compared to wild-type IL-2 for use in combination therapies with anti-PD-1 antibodies for the treatment of cancer. Also provided are pharmaceutical compositions that include such anti-PD-1 antibodies and the disclosed IL-2 muteins.
    Type: Grant
    Filed: June 19, 2018
    Date of Patent: January 3, 2023
    Assignee: Medicenna Therapeutics, Inc.
    Inventors: Fahar Merchant, Shafique Fidai
  • IL-2 SUPERAGONISTS IN COMBINATION WITH ANTI-PD-1 ANTIBODIES
    Publication number: 20190062395
    Abstract: Human interleukin-2 (IL-2) muteins or variants thereof are provided. In particular, provided are IL-2 muteins that have an increased binding capacity for IL-2R? receptor as compared to wild-type IL-2 for use in combination therapies with anti-PD-1 antibodies for the treatment of cancer. Also provided are pharmaceutical compositions that include such anti-PD-1 antibodies and the disclosed IL-2 muteins.
    Type: Application
    Filed: June 19, 2018
    Publication date: February 28, 2019
    Inventors: Fahar Merchant, Shafique Fidai
  • ANTIMICROBIAL AND ANTI-INFLAMMATORY PEPTIDES
    Publication number: 20180289768
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Application
    Filed: December 7, 2017
    Publication date: October 11, 2018
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
  • Antimicrobial and anti-inflammatory peptides
    Patent number: 9872885
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: January 23, 2018
    Assignee: CARRUS CAPITAL CORPORATION
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
  • ANTIMICROBIAL AND ANTI-INFLAMMATORY PEPTIDES
    Publication number: 20150343015
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Application
    Filed: December 17, 2014
    Publication date: December 3, 2015
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger
  • Antimicrobial and anti-inflammatory peptides
    Patent number: 8933029
    Abstract: Antimicrobial and/or anti-inflammatory peptide compositions and therapeutic uses thereof are provided. The peptides and analogs or derivatives thereof may be used as an antimicrobial agent and/or as an anti-inflammatory agent. In certain embodiments, the peptides are cationic peptides. The peptides are useful for the treatment of inflammatory diseases, such as microorganism-caused infections, acne, and psoriasis. The peptides and peptide formulations may be used topically or parenterally.
    Type: Grant
    Filed: August 26, 2002
    Date of Patent: January 13, 2015
    Assignee: Carrus Capital Corporation
    Inventors: Patricia J. McNicol, Sonia K. Pawlak, Evelina Rubinchik, Dale Cameron, Maria Marta Guarna, Janet R. Fraser, Shafique Fidai, Yuchen Chen, Timothy J. Krieger