Patents by Inventor Shahid M. NIMJEE

Shahid M. NIMJEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Von Willebrand Factor (VWF)-targeting agents and methods of using the same
    Patent number: 11965160
    Abstract: Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: April 23, 2024
    Assignees: Duke University, Ohio State Innovation Foundation
    Inventors: Shahid M. Nimjee, Bruce Sullenger, George A. Pitoc, Juliana Layzer
  • VON WILLEBRAND FACTOR (VWF)-TARGETING AGENTS AND METHODS OF USING THE SAME
    Publication number: 20210222170
    Abstract: Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.
    Type: Application
    Filed: January 11, 2021
    Publication date: July 22, 2021
    Applicants: Duke University, Ohio State Innovation Foundation
    Inventors: Shahid M. NIMJEE, Bruce SULLENGER, George A. PITOC, Juliana LAYZER
  • Von Willebrand Factor (VWF)—targeting agents and methods of using the same
    Patent number: 10889816
    Abstract: Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: January 12, 2021
    Assignees: DUKE UNIVERSITY, OHIO STATE INNOVATION FOUNDATION
    Inventors: Shahid M. Nimjee, George A. Pitoc, Juliana Layzer, Bruce Sullenger
  • VON WILLEBRAND FACTOR (VWF)-TARGETING AGENTS AND METHODS OF USING THE SAME
    Publication number: 20190218553
    Abstract: Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.
    Type: Application
    Filed: September 18, 2017
    Publication date: July 18, 2019
    Applicants: DUKE UNIVERSITY, OHIO STATE INNOVATION FOUNDATION
    Inventors: Shahid M. NIMJEE, George A. PITOC, Juliana LAYZER, Bruce SULLENGER