Patents by Inventor Shahid Malik

Shahid Malik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Separation of ginkgolides and bilobalide from
    Patent number: 7763741
    Abstract: The subject invention provides a method for separating a terpene trilactone from Ginkgo biloba plant material or from an extract of Ginkgo biloba comprising a mixture of terpene trilactones, the process comprising the steps of: a) subjecting the Ginkgo biloba plant material or the extract to column chromatography with an appropriate solvent system to produce at least a first fraction containing the terpene trilactone bilobalide, a second fraction eluted after the first fraction containing the terpene trilactones GA and GB, and a third fraction eluted after the second fraction containing at least a preponderance of the terpene trilactones GC and GJ; and b) alkylating the terpene trilactone GB of the second fraction so as to produce a first mixture including terpene trilactone GA and alkylated terpene trilactone GB; or alkylating the terpene trilactone GC of the third fraction so as produce a second mixture including terpene trilactone GJ and alkylated terpene trilactone GC, so as to thereby isolate a terpen
    Type: Grant
    Filed: November 9, 2004
    Date of Patent: July 27, 2010
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Koji Nakanishi, Stanislav Jaracz, Shahid Malik, Hideki Ishii, Sergei V. Dzyuba
  • Separation Of Ginkgolides And Bilobalide From G. Biloba
    Publication number: 20080108837
    Abstract: The subject invention provides a method for separating a terpene trilactone from Ginkgo biloba plant material or from an extract of Ginkgo biloba comprising a mixture of terpene trilactones, the process comprising the steps of: a) subjecting the Ginkgo biloba plant material or the extract to column chromatography with an appropriate solvent system to produce at least a first fraction containing the terpene trilactone bilobalide, a second fraction eluted after the first fraction containing the terpene trilactones GA and GB, and a third fraction eluted after the second fraction containing at least a preponderance of the terpene trilactones GC and GJ; and b) alkylating the terpene trilactone GB of the second fraction so as to produce a first mixture including terpene trilactone GA and alkylated terpene trilactone GB; or alkylating the terpene trilactone GC of the third fraction so as produce a second mixture including terpene trilactone GJ and alkylated terpene trilactone GC, so as to thereby isolate a terpene t
    Type: Application
    Filed: November 9, 2004
    Publication date: May 8, 2008
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Koji Nakanishi, Stanislav Jaracz, Shahid Malik, Hideki Ishii, Sergei V. Dzyuba