Abstract: Apparatus for measuring sural nerve conduction velocity and amplitude, the apparatus comprising: a housing; stimulation means mounted to the housing for electrically stimulating a human sural nerve; a biosensor releasably mounted to the housing, the biosensor comprising a plurality of electrodes for detecting a sural nerve response evoked by the stimulation means; acquisition means mounted to the housing and electrically connected to the biosensor for electrically acquiring the sural nerve response detected by the biosensor; processing means mounted to the housing and electrically connected to the acquisition means for digitizing, processing and storing the acquired sural nerve response; calculation means mounted to the housing and electrically connected to the processing means for calculating the conduction velocity and amplitude of the processed sural nerve response; and display means mounted to the housing for displaying the sural nerve conduction velocity and amplitude; wherein the stimulation means an

Abstract: Apparatus for measuring sural nerve conduction velocity and amplitude, the apparatus including a housing; stimulation means for electrically stimulating a human sural nerve; a biosensor comprising a plurality of electrodes for detecting a sural nerve response evoked by the stimulation means; acquisition means electrically connected to the biosensor for electrically acquiring the sural nerve response detected by the biosensor; processing means electrically connected to the acquisition means for digitizing, processing and storing the acquired sural nerve response; calculation means electrically connected to the processing means for calculating the conduction velocity and amplitude of the processed sural nerve response; and display means for displaying the sural nerve conduction velocity and amplitude; wherein the stimulation means and the biosensor are designed to be placed on a patient's anatomy, in the vicinity of a sural nerve.

Abstract: A method and apparatus for the assessment of neuromuscular function by estimating motor unit F-wave component time of arrival (TOA), comprising: (i) determining and comparing F-wave component features so as to accurately identify individual F-wave components; (ii) repeatedly searching the individual F-wave components and extracting individual F-wavelets from the F-wave components so as to build a complete F-wave TOA profile; and (iii) computing and reporting TOA results for the assessment of neuromuscular function.

Abstract: Apparatus for providing transcutaneous electrical nerve stimulation (TENS) therapy to a user, the apparatus comprising: a stimulation unit for electrically stimulating at least one nerve of the user; an electrode array connectable to the stimulation unit, the electrode array comprising a plurality of electrodes for electrical stimulation of the at least one nerve of the user; a monitoring unit electrically connected to the stimulation unit for monitoring the on-skin status of the electrode array; an analysis unit for analyzing the on-skin status of the electrode array to determine the effective on-skin time of the electrode array; and a feedback unit for alerting the user when the analysis unit determine that the effective on-skin time exceeds a threshold.

Abstract: Apparatus for transcutaneous electrical nerve stimulation in humans, the apparatus comprising: a housing; stimulation means mounted within the housing for electrically stimulating nerves; an electrode array releasably mounted to the housing and connectable to the stimulation means, the electrode array comprising a plurality of electrodes for electrical stimulation of nerves; control means mounted to the housing and electrically connected to the stimulation means for controlling at least one characteristic of the stimulation means; monitoring means mounted to the housing and electrically connected to the stimulation means for monitoring at least one characteristic of the stimulation means; user interface means mounted to the housing and electrically connected to the control means for controlling the stimulation means; display means mounted to the housing and electrically connected to the control means and the monitoring means for displaying the status of the stimulations means; and a strap attached to the h

Abstract: A method for the automated removal of a stimulus artifact from an electrophysiological signal waveform, wherein the novel method comprises: providing a model of the stimulus artifact that is physically derived and is based on known properties of the electrophysiological signal waveform acquisition hardware and stimulator; and filtering the stimulus artifact out of the electrophysiological signal waveform using the model.

Abstract: Apparatus for transcutaneous electrical nerve stimulation in humans, comprising a housing; stimulation means mounted within the housing for electrically stimulating nerves; an electrode array releasably mounted to the housing, connectable to the stimulation means, and comprising electrodes for electrical stimulation of nerves; control means mounted to the housing and electrically connected to the stimulation means for controlling the stimulation means; monitoring means mounted to the housing and electrically connected to the stimulation means for monitoring the stimulation means; user interface means mounted to the housing and electrically connected to the control means for controlling the stimulation means; display means mounted to the housing and electrically connected to the control means and the monitoring means for displaying the status of the stimulations means; and a strap attached to the housing and configured to hold the housing, stimulation means and electrode array at a specific anatomical location

Abstract: Apparatus for transcutaneous electrical nerve stimulation in a user, the apparatus comprising: a housing; stimulation means carried by the housing for electrically stimulating at least one nerve; a pair of electrodes releasably mounted to the housing and connectable to the stimulation means for electrical stimulation of the at least one nerve; monitoring means for monitoring user gesture, electrode-skin contact integrity and transient motion; analysis means for analyzing the output of the monitoring means for determining user gesture, electrode-skin contact integrity and transient motion; and control means for controlling the output of the stimulation means in response to the determined user gesture, electrode-skin contact integrity and transient motion.

Abstract: A novel submaximal F-wave acquisition and analysis system that employs computational intelligence to set up submaximal F-wave acquisition conditions and to extract submaximal F-wave features automatically, without operator intervention.

Abstract: Apparatus comprising a housing; stimulation means mounted to the housing; a biosensor releasably mounted to the housing, the biosensor comprising a plurality of electrodes for detecting a sural nerve response evoked by the stimulation means; acquisition means mounted to the housing and electrically connected to the biosensor for acquiring the sural nerve response; processing means mounted to the housing and electrically connected to the acquisition means for digitizing, processing and storing the acquired sural nerve response; calculation means mounted to the housing and electrically connected to the processing means for calculating the conduction velocity and amplitude of the processed sural nerve response; and display means mounted to the housing for displaying the sural nerve conduction velocity and amplitude; wherein the stimulation means and the biosensor are designed to be placed on a patient's anatomy, in the vicinity of a sural nerve, by manipulating the housing.

Abstract: This invention relates to the detection of bioelectric signals indicative of neuromuscular function. A mapping biosensor array is first used to identify, relative to reliable anatomical landmarks, the optimal myoelectrical detection site for the majority of the population. Then a diagnostic biosensor array is fabricated using this information so that when the diagnostic biosensor array is positioned on an individual using the reliable anatomical landmarks, the detection electrode is automatically positioned over the optimal detection site.

Abstract: In one form of the present invention, there is provided a method for detecting an A-wave, the method comprising: applying a series of stimuli to a nerve; recording a series of late responses; creation of a feature space map from an ensemble of late responses; identification of clusters within the feature space that represent A-wave components; consolidation of A-wave components into a discrete collection of A-waves; removal of false positive A-waves; and extraction of A-wave characteristics.

Abstract: A method for the assessment of neuromuscular function by motor unit number estimation, comprising: (i) determining and controlling stimulation and data acquisition process via pre-configured electrode array so as to acquire stable and less uncertainty MU responses; (ii) pre-processing acquired MUs responses so as to attenuate noise, determine MUs activity region, and improve processing speed and accuracy; (iii) minimizing alternation effects by globally searching and comparing SMUPs; (iv) eliminating alternation effects by identifying alternating MUs directly; and (v) computing and reporting MUNE results, as well as the statistical description of these MUN estimates to evaluate its robustness.

Abstract: An apparatus and method for detecting physiological function, for example, nerve conduction, is described. In one embodiment the apparatus includes a housing including a stimulator shaped to fit a first anatomical site and a detector shaped to fit a second anatomical site. The housing automatically positions the detector substantially adjacent to the second anatomical site when the stimulator is positioned substantially adjacent to the first anatomical site. The detector contains a plurality of individual detection elements, whereby the response evoked by stimulation at the first anatomical site is measured using one or more of these detection elements at the second anatomical location.

Abstract: A multi-electrode assembly for use in neuromuscular testing, the multi-electrode assembly comprising: a substrate; at least one stimulation electrode carried by the substrate; at least one detection electrode carried by the substrate; a connector carried by the substrate, the connector being configured for connection with testing electronics; and a plurality of traces for electrically connecting the at least one stimulation electrode and the at least one detection electrode to the connector; wherein the substrate is flexible so that the at least one stimulation electrode and the at least one detection electrode are independently positionable on a patient.