Patents by Inventor Shaila Rahman

Shaila Rahman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome
    Patent number: 11672834
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: June 13, 2023
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Shaila Rahman
  • Probiotic compositions containing clostridiales for inhibiting inflammation
    Patent number: 11612622
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: March 28, 2023
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • Probiotic compositions containing clostridiales for inhibiting inflammation
    Patent number: 11607432
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: March 21, 2023
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND METHODS OF USE THEREOF FOR MODULATION OF THE MICROBIOME
    Publication number: 20220323511
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Application
    Filed: March 26, 2021
    Publication date: October 13, 2022
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Shaila Rahman
  • Nutritive polypeptides and formulations thereof, and methods of production and use thereof
    Patent number: 11357824
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: June 14, 2022
    Assignee: Axcella Health Inc.
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • Probiotic and prebiotic compositions, and methods of use thereof for modulation of the microbiome
    Patent number: 10980845
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: April 20, 2021
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Shaila Rahman
  • Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
    Patent number: 10869903
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: December 22, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Neal Gordon, Shaila Rahman
  • Nutritive Polypeptides and Formulations Thereof, and Methods of Production and Use Thereof
    Publication number: 20200306342
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Application
    Filed: March 16, 2020
    Publication date: October 1, 2020
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • Nutritive Polypeptides and Formulations Thereof, and Methods of Production and Use Thereof
    Publication number: 20200188481
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Application
    Filed: September 27, 2019
    Publication date: June 18, 2020
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • PROBIOTIC COMPOSITIONS CONTAINING CLOSTRIDIALES FOR INHIBITING INFLAMMATION
    Publication number: 20200061129
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Application
    Filed: August 23, 2019
    Publication date: February 27, 2020
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • PROBIOTIC COMPOSITIONS CONTAINING CLOSTRIDIALES FOR INHIBITING INFLAMMATION
    Publication number: 20190336543
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Application
    Filed: December 13, 2018
    Publication date: November 7, 2019
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • Nutritive polypeptides and formulations thereof, and methods of production and use thereof
    Patent number: 10463711
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: November 5, 2019
    Assignee: Axcella Health Inc.
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND METHODS OF USE THEREOF FOR TREATMENT AND PREVENTION OF GRAFT VERSES HOST DISEASE
    Publication number: 20180169153
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.
    Type: Application
    Filed: July 31, 2017
    Publication date: June 21, 2018
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Neal Gordon, Shaila Rahman
  • PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND METHODS OF USE THEREOF FOR TREATMENT AND PREVENTION OF GRAFT VERSUS HOST DISEASE
    Publication number: 20180071344
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.
    Type: Application
    Filed: April 24, 2017
    Publication date: March 15, 2018
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Neal Gordon, Shaila Rahman
  • PROBIOTIC COMPOSITIONS CONTAINING CLOSTRIDIALES FOR INHIBITING INFLAMMATION
    Publication number: 20180015130
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Application
    Filed: February 21, 2017
    Publication date: January 18, 2018
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • Probiotic compositions containing clostridiales for inhibiting inflammation
    Patent number: 9610307
    Abstract: Pharmaceutical compositions containing microbial entities are described herein. The pharmaceutical compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the pharmaceutical compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: April 4, 2017
    Assignee: Evelop Biosciences, Inc.
    Inventors: David Berry, Johanne Kaplan, Shaila Rahman
  • Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease
    Patent number: 9603878
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial or fungal entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent transplant disorders, e.g., graft-versus-host disease (GVHD), in a subject are also provided.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: March 28, 2017
    Assignee: Evelo Biosciences, Inc.
    Inventors: David Berry, Shaila Rahman, Johanne Kaplan, Neal Gordon
  • NSD3 INHIBITORS FOR TREATMENT OF CANCERS
    Publication number: 20170007595
    Abstract: The present invention relates to the use of NSD3i inhibitors for the treatment of cancer. In particular, the present invention relates to methods, kits and compositions comprising NSD3 inhibitors to treat cancers dependent on NSD3, in particular subjects with NUT midline carcinoma (NMC) and subjects with NSD3/NUT or BRD4/NUT or BRD3/NUT fusion genes, as well as subjects with BRD4-dependent (but NUT-independent cancers). The present invention also relates to methods, kits and compositions comprising BET inhibitors for the treatment of subjects with NSD3/NUT fusion genes. Other aspects of the invention relate to assays and methods to identify an inhibitor of NSD3 which disrupts or decreases the interaction of the NSD3 protein with the ET do main of BRD4.
    Type: Application
    Filed: January 23, 2015
    Publication date: January 12, 2017
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Christopher A. FRENCH, Peter M. HOWLEY, Erica Marlene WALSH MICHEL, Shaila RAHMAN, Simone KUHNLE
  • Nutritive Polypeptides and Formulations Thereof, and Methods of Production and Use Thereof
    Publication number: 20160339078
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Application
    Filed: March 25, 2016
    Publication date: November 24, 2016
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • PROBIOTIC AND PREBIOTIC COMPOSITIONS, AND METHODS OF USE THEREOF FOR TREATMENT OF GASTROINTESTINAL DISORDERS
    Publication number: 20160271188
    Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome, e.g., gastrointestinal disorders, in a subject are also provided.
    Type: Application
    Filed: November 25, 2015
    Publication date: September 22, 2016
    Inventors: David Berry, Noubar B. Afeyan, Johanne Kaplan, Shaila Rahman