Patents by Inventor Shailendra K. Saxena

Shailendra K. Saxena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Methods of treating infections originating from viruses in the herpesviridae family

Patent number: 8808690

Abstract: Three RNases (ranpirnase, the second embodiment disclosed in U.S. Pat. No. 5,728,805, and recombinant Amphinase-2) are tested against identified herpesviridae infections. With some exceptions, quantitative PCR assays indicate that the RNases have anti-viral activity against many of these viruses.

Type: Grant

Filed: July 26, 2013

Date of Patent: August 19, 2014

Assignee: Tamir Biotechnology, Inc.

Inventors: Shailendra K. Saxena, Wojciech Ardelt
Methods of treating human papillomavirus

Patent number: 8663964

Abstract: Two RNases (ranpirnase and the second embodiment disclosed in U.S. Pat. No. 5,728,805) are tested against human papillomavirus infections. QRT-PCR assays indicate that the RNases have anti-viral activity against type 11 HPV.

Type: Grant

Filed: July 20, 2011

Date of Patent: March 4, 2014

Assignee: Tamir Biotechnology, Inc.

Inventors: Shailendra K. Saxena, Wojciech Ardelt
METHODS OF TREATING INFECTIONS ORIGINATING FROM VIRUSES IN THE HERPESVIRIDAE FAMILY

Publication number: 20140037610

Abstract: Three RNases (ranpirnase, the second embodiment disclosed in U.S. Pat. No. 5,728,805, and recombinant Amphinase-2) are tested against identified herpesviridae infections. With some exceptions, quantitative PCR assays indicate that the RNases have anti-viral activity against many of these viruses.

Type: Application

Filed: July 26, 2013

Publication date: February 6, 2014

Applicant: Tamir Biotechnology, Inc.

Inventors: Shailendra K. SAXENA, Wojciech ARDELT
METHODS OF TREATING KAPOSI'S SARCOMA

Publication number: 20140030246

Abstract: Three RNases (ranpirnase, the second embodiment disclosed in U.S. Pat. No. 5,728,805, and recombinant Amphinase-2) are tested against identified herpesviridae infections. With some exceptions, quantitative PCR assays indicate that the RNases have anti-viral activity against many of these viruses.

Type: Application

Filed: July 26, 2013

Publication date: January 30, 2014

Applicant: Tamir Biotechnology, Inc.

Inventors: Shailendra K. SAXENA, Wojciech ARDELT
Methods of treating infections originating from viruses in the herpesviridae family

Patent number: 8518399

Abstract: Three RNases (ranpirnase, the second embodiment disclosed in U.S. Pat. No. 5,728,805, and recombinant Amphinase-2) are tested against identified herpesviridae infections. With some exceptions, quantitative PCR assays indicate that the RNases have anti-viral activity against many of these viruses.

Type: Grant

Filed: November 17, 2010

Date of Patent: August 27, 2013

Assignee: Tamir Biotechnology, Inc.

Inventors: Shailendra K. Saxena, Wojciech Ardelt
METHODS OF TREATING HUMAN PAPILLOMAVIRUS

Publication number: 20130022589

Abstract: Two RNases (ranpirnase and the second embodiment disclosed in U.S. Pat. No. 5,728,805) are tested against human papillomavirus infections. QRT-PCR assays indicate that the RNases have anti-viral activity against type 11 HPV.

Type: Application

Filed: July 20, 2011

Publication date: January 24, 2013

Applicant: TAMIR BIOTECHNOLOGY, INC.

Inventors: Shailendra K. Saxena, Wojciech Ardelt
METHODS OF TREATING INFECTIONS ORIGINATING FROM VIRUSES IN THE HERPESVIRIDAE FAMILY

Publication number: 20120121569

Abstract: Three RNases (ranpirnase, the second embodiment disclosed in U.S. Pat. No. 5,728,805, and recombinant Amphinase-2) are tested against identified herpesviridae infections. With some exceptions, quantitative PCR assays indicate that the RNases have anti-viral activity against many of these viruses.

Type: Application

Filed: November 17, 2010

Publication date: May 17, 2012

Applicant: Tamir Biotechnology, Inc.

Inventors: Shailendra K. Saxena, Wojciech Ardelt
RELATED RIBONUCLEASES IN WHICH AN AMINO ACID SEQUENCE OF A KNOWN RIBONUCLEASE IS PRECEDED BY AT LEAST ONE RESIDUE AT THE N-TERMINUS, AND METHODS OF MAKING THEM RECOMBINANTLY

Publication number: 20100317082

Abstract: New RNases, and methods for making them, are disclosed. Each includes an amino acid sequence that is disclosed in U.S. Pat. No. 6,239,257 B1, but that is preceded by a different N-terminus residue or leader sequence.

Type: Application

Filed: June 1, 2010

Publication date: December 16, 2010

Applicant: ALFACELL CORPORATION

Inventor: Shailendra K. SAXENA
RIBONUCLEASE IN WHICH AN AMINO ACID SEQUENCE OF A KNOWN RIBONUCLEASE IS PRECEDED BY A RESIDUE AT THE N-TERMINUS, AND A METHOD OF MAKING IT RECOMBINANTLY

Publication number: 20100304463

Abstract: A new RNase, and a method for making it, are disclosed. The RNase has an amino acid sequence that is disclosed in U.S. Pat. No. 6,239,257 B1, but that is preceded by a different N-terminus residue.

Type: Application

Filed: May 28, 2010

Publication date: December 2, 2010

Applicant: ALFACELL CORPORATION

Inventor: Shailendra K. SAXENA
RIBONUCLEASES IN WHICH AN AMINO ACID SEQUENCE OF A KNOWN RIBONUCLEASE IS PRECEDED BY AT LEAST ONE RESIDUE AT THE N-TERMINUS, AND METHODS OF MAKING THEM RECOMBINANTLY

Publication number: 20100291657

Abstract: New RNases, and methods of making them, are disclosed. Each includes an amino acid sequence that is disclosed in U.S. Pat. No. 6,239,257 B1, but that is preceded by a different N-terminus residue or leader sequence.

Type: Application

Filed: June 9, 2010

Publication date: November 18, 2010

Applicant: ALFACELL CORPORATION

Inventor: Shailendra K. SAXENA
Nucleic acid encoding a novel ribonuclease having an amino acid sequence made up of the amino acid sequence of a known ribonuclease and an N-terminal leader sequence that is at least one residue long

Patent number: 7763449

Abstract: A nucleic acid encodes a novel RNase. The RNase has an amino acid sequence in which an amino acid sequence disclosed in U.S. Pat. No. 6,239,257 B1 is preceded by a different N-terminal residue or leader sequence.

Type: Grant

Filed: November 19, 2008

Date of Patent: July 27, 2010

Assignee: Alfacell Corporation

Inventor: Shailendra K. Saxena
Nucleic acid encoding cysteinized ribonuclease to which a targeting moiety can be conjugated

Patent number: 7585654

Abstract: A nucleic acid encodes a cysteinized RNase to which a targeting moiety can be conjugated.

Type: Grant

Filed: November 20, 2008

Date of Patent: September 8, 2009

Assignee: Alfacell Corporation

Inventor: Shailendra K. Saxena
Nucleic acid encoding a fusion protein incorporating a cysteinized ribonuclease

Patent number: 7585655

Abstract: A nucleic acid encodes a novel fusion protein. The fusion protein contains a cysteinized variant of an RNase disclosed in U.S. Pat. No. 6,239,257 B1.

Type: Grant

Filed: November 20, 2008

Date of Patent: September 8, 2009

Assignee: Alfacell Corporation

Inventor: Shailendra K. Saxena
Nucleic acid encoding a novel ribonuclease having an amino acid sequence made up of a known amino acid sequence and an initial N-terminal residue

Patent number: 7556952

Abstract: A nucleic acid encodes a novel RNase. The RNase has an amino acid sequence in which an amino acid sequence disclosed in U.S. Pat. No. 6,239,257 B1 is preceded by a different N-terminal residue.

Type: Grant

Filed: November 19, 2008

Date of Patent: July 7, 2009

Assignee: Alfacell Corporation

Inventor: Shailendra K. Saxena
Nucleic acid encoding a novel ribonuclease having an amino acid sequence made up of the amino acid sequence of a known ribonuclease and an N-terminal leader sequence

Patent number: 7556953

Abstract: A nucleic acid encodes a novel RNase. The RNase has an amino acid sequence in which an amino acid sequence disclosed in U.S. Pat. No. 6,239,257 B1 is preceded by a leader sequence.

Type: Grant

Filed: November 20, 2008

Date of Patent: July 7, 2009

Assignee: Alfacell Corporation

Inventor: Shailendra K. Saxena
Nucleic acid encoding a novel ribonuclease having an amino acid sequence made up of the amino acid sequence of a known ribonuclease and an n-terminal leader sequence that is at least one residue long

Patent number: 7556951

Abstract: A nucleic acid encodes a novel RNase. The RNase has an amino acid sequence in which an amino acid sequence disclosed in United States Patent U.S. Pat. No. 6,239,257 B1 is preceded by a different N-terminal residue or leader sequence.

Type: Grant

Filed: November 18, 2008

Date of Patent: July 7, 2009

Assignee: Alfacell Corporation

Inventor: Shailendra K. Saxena
NUCLEIC ACID ENCODING A NOVEL RIBONUCLEASE HAVING AN AMINO ACID SEQUENCE MADE UP OF THE AMINO ACID SEQUENCE OF A KNOWN RIBONUCLEASE AND AN N-TERMINAL LEADER SEQUENCE

Publication number: 20090111175

Abstract: A nucleic acid encodes a novel RNase. The RNase has an amino acid sequence in which an amino acid sequence disclosed in U.S. Pat. No. 6,239,257 B1 is preceded by a leader sequence.

Type: Application

Filed: November 20, 2008

Publication date: April 30, 2009

Applicant: ALFACELL CORPORATION

Inventor: Shailendra K. SAXENA
NUCLEIC ACID ENCODING A NOVEL RIBONUCLEASE HAVING AN AMINO ACID SEQUENCE MADE UP OF A KNOWN AMINO ACID SEQUENCE AND AN INITIAL N-TERMINAL RESIDUE

Publication number: 20090099348

Abstract: A nucleic acid encodes a novel RNase. The RNase has an amino acid sequence in which an amino acid sequence disclosed in U.S. Pat. No. 6,239,257 B1 is preceded by a different N-terminal residue.

Type: Application

Filed: November 19, 2008

Publication date: April 16, 2009

Applicant: ALFACELL CORPORATION

Inventor: Shailendra K. SAXENA
NUCLEIC ACID ENCODING CYSTEINIZED RIBONUCLEASE TO WHICH A TARGETING MOIETY CAN BE CONJUGATED

Publication number: 20090081777

Abstract: A nucleic acid encodes a cysteinized RNase to which a targeting moiety can be conjugated.

Type: Application

Filed: November 20, 2008

Publication date: March 26, 2009

Applicant: ALFACELL CORPORATION

Inventor: Shailendra K. SAXENA
NUCLEIC ACID ENCODING A NOVEL RIBONUCLEASE HAVING AN AMINO ACID SEQUENCE MADE UP OF THE AMINO ACID SEQUENCE OF A KNOWN RIBONUCLEASE AND AN N-TERMINAL LEADER SEQUENCE THAT IS AT LEAST ONE RESIDUE LONG

Publication number: 20090081776

Abstract: A nucleic acid encodes a novel RNase. The RNase has an amino acid sequence in which an amino acid sequence disclosed in U.S. Pat. No. 6,239,257 B1 is preceded by a different N-terminal residue or leader sequence.

Type: Application

Filed: November 19, 2008

Publication date: March 26, 2009

Applicant: ALFACELL CORPORATION

Inventor: Shailendra K. SAXENA

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