Abstract: The present invention relates to sulphur-containing oils, their preparation, and their use in controlling/killing plant pathogens and stimulating a plant's uptake of essential elements from the soil and to act as a soil pH adjuster.

Abstract: Provided are processes for desilylating carbapenem intermediates. In particular, such desilylation reactions are done in the presence of one or more desilylating agents selected from acetyl chloride, silica chloride, thionyl chloride, oxalyl chloride or mixtures thereof.

Abstract: The invention relates to a process for enrichment of the (Z)-isomer amount in a mixture of the (Z)- and (E)-isomers of 7-amino-3-(1-propen-1-yl)-3-cephem-4-carboxylic acid.

Abstract: The present invention relates to a process for the preparation of cefdinir on an industrial scale.

Abstract: An integrated desktop analytic device comprises a fluidics station coupled to a confocal microscope detector, and a biochip is moved from the fluidics station to the detector without manual intervention of an operator.

Abstract: Various methods are provided for an integrated micro array system (100) that allows fully automated sample processing and detection/quantification of nucleic acid and protein samples in a single analytical device, which may be configured to communicate data to a person other than the person operating the device. The integrated micro array system has a housing (110) in which robotics assembly (120) controls motion of automatic pipette (124) and second actuator (122) that control motion of the automatic actuator (123). Fluidics station (130) includes a plurality of multi-reagent packs (132). Sample station (140) comprises a plurality of sample vessels (142). Pipette tip storage area (150) and magazine holder (160) that includes a plurality of magazine (162). The system also comprise of a sample processing platform (170), a stringency station (181), and optical detector (180), and a data transfer device (190).

Abstract: A multi-reagent pack has a plurality of reagent compartments and further includes a read-write memory chip that carries data pertaining to a particular test protocol that employs reagents from the reagent compartments. Data may be transferred between the reagent pack and an analytic device, and optionally further to a supplier.

Abstract: Diol-functionalized antioxidants and the process for the preparation thereof are disclosed and have the general formula (I): wherein: R1 is tert-butyl and R2 is C1 to C8 linear or branched alkyl. The invention also pertains to a process for their preparation. Which comprises: Reacting a halo functionalized antioxidant having the general formula (II): wherein: R1 is tert-butyl and X is bromide (Br) with a diol having general formula (IV): wherein R2 is C1 to C8 linear or branched alkyl.

Abstract: An automatic pipette in an analytic device uses disposable pipette tips, and in which proper coupling of the pipette tip to the pipette, accurate volume of the aspirated fluid, and distance of the pipette tip to a biochip are determined using a plurality of sensors that are coupled to the automatic pipette.

Abstract: A detector for optical analysis of a biochip determines the focal position of a plurality of analytes on the biochip using one or more registration markers on the biochip, wherein the analytes and the registration marker are illuminated by different light sources. Therefore, contemplated configurations will significantly reduce overall focusing time and automate proper positioning of the biochip, while allowing to determine a focal position without photobleaching or other undesirable effects on optically labile compounds. Thus, automated analyses can be performed without manual user intervention.

Abstract: The present invention relates to a novel crystalline cefdinir potassium dihydrate, to a process for its preparation and to a method of preparing pure cefdinir via the crystalline salt.

Abstract: An analytical device has a housing that encloses a multi-substrate chip having a reference marker and a plurality of substrates, wherein the housing is configured such that the reference marker and the substrates are illuminated by respective light sources at different angles. Further contemplated analytical devices include a housing with a cavity in which a multi-substrate chip having a plurality of substrates is at least partially disposed, wherein at least one of the plurality of substrates is coupled to a carrier via a crosslinker that is disposed in a matrix.

Abstract: Diol-functionalized antioxidants and the process for the preparation thereof are disclosed and have the general formula (I): 1

Abstract: The present invention relates to a novel antiozonant as well as antioxidant based on functionalized hindered phenol and the process for the preparation thereof of formula 1 wherein R1 is tert-butyl and R2 and R3 are C1 to C8 linear or branched alkyl. The present invention also relates to a process for the preparation thereof comprising dissolving a compound of formula 3 wherein R1 is tert-butyl, with liquid bromine in a non polar organic solvent at temperature range 80 to 95° C. for a period of 4 to 7 hours, evaporating the solvent under reduced pressure to obtain a compound of formula 2 wherein R1 is a tertiary butyl group and X is Br, reacting the compound of formula 2 with a compound of formula 4 wherein R2 and R3 are C1 to C8 linear or branched alkyl, dissolved in an organic solvent in presence of a suitable mild base at a temperature ranging from 80 to 95° C.

Abstract: A temperature controlled chamber for an analytical instrument which includes a circular conveyor for transporting assay cartridges, the chamber enclosing the outer peripheral part of the conveyor on which the assay cartridges reside. The temperature controlled chamber has a bottom wall of polymeric material located beneath the conveyor, an outer wall of polymeric material extending upward above the conveyor, a metallic top wall and a metallic inner wall which extends downward to the upper surface of the conveyor. Thermal control, including rapid thermal response to compensate for temperature perturbations induced by periodic introduction of assay cartridges which are at a temperature less than that of the chamber, is accomplished by heating elements located above and below the conveyor. The heating elements are pulsed by an electrical circuit at a rate substantially faster than the rate of introduction of new assay cartridges.

Abstract: There is described an analytical isntrument for the analysis of fluids such as biological fluids. The instrument includes a fluid dispensing system having a pipette for dispensing fluid test samples and test reagents to assay cartridges. An optical detection system provides a light beam which intercepts a downward travel path of the pipette prior to its reaching the dispense position. Measurement of the intensity of the light beam in conjunction with the position of the pipette enables a controller to indicate the presence or absence of a pipette tip. In addition, interception of the light beam by the pipette initiates a final approach sequence for the pipette to the dispense position above an assay cartridge by a predetermined increment of travel.