Abstract: A nano-emulsion composition for skin care application is provided. The nano-emulsion composition being oil-in-water composition. The nano-emulsion composition includes at least one oil, at least one hydrophilic compound to create an aqueous phase, at least one water soluble phytoactive compound, and at least one oil soluble phytoactive compound. The nano-emulsion composition also includes a combination of polyglycerol fatty acid esters as emulsifiers. The combination of polyglycerol fatty acid esters comprises a first polyglycerol fatty acid ester and a second polyglycerol fatty acid ester in a ratio of 1:1. Further the nano-emulsion composition includes at least one preservative. The nano-emulsion composition being a low viscous fluidic vehicle to be used as serum, micellar water, facial cleanser etc. The nano-emulsion composition being capable of retaining high storage stability over a wider temperature range.