Patents by Inventor Shailesh Singh

Shailesh Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8240993
    Abstract: An air distribution system for manipulating a boundary layer of air across a wind turbine rotor blade. The wind turbine rotor blade includes at least one sidewall that defines a cavity therein. The sidewall extends between a leading edge and an axially-spaced trailing edge, and defines a chordwise axis between the leading edge and the trailing edge. The air distribution system includes a plurality of bleed flow assemblies that are positioned within the rotor blade and are configured to discharge air into the boundary layer to reduce a separation of the boundary layer from the rotor blade. Each bleed flow assembly of the plurality of bleed flow assemblies includes a bleed flow conduit that is coupled to an inner surface of the sidewall and is oriented with respect to the chordwise axis between the leading edge and the trailing edge. The bleed flow conduit is configured to channel air through the rotor blade.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: August 14, 2012
    Assignee: General Electric Company
    Inventors: Shailesh Singh Bhaisora, Narasimha Shastri, Anurag Gupta
  • Patent number: 8231907
    Abstract: Milled nanoparticles comprising a biologically active agent, at least one biopolymer and a coating containing at least one coating which is a polymer or ligand.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: July 31, 2012
    Assignee: Morehouse School of Medicine
    Inventors: James W. Lillard, Rajesh Singh, Shailesh Singh
  • Publication number: 20120135415
    Abstract: Methods for diagnosing cancer in a subject are disclosed. The method includes detecting the level of expression of one or more cancer markers in a biological sample obtained from the subject; and comparing the level of expression of the one or more cancer markers in the biological sample to a normal level of expression of the one or more cancer markers. The one or more cancer markers comprises CXCL13 or CXCR5 or both CXCL13 and CXCR5. Also disclosed is a kit for detecting cancer or monitoring cancer progression.
    Type: Application
    Filed: December 7, 2011
    Publication date: May 31, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Rajesh Singh, Shailesh Singh
  • Publication number: 20120128688
    Abstract: Methods for prevention or inhibition of the growth or metastasis of cancer cells in a subject are disclosed. One method comprises the step of administering to the subject a therapeutically effective amount of an antibody to the chemokine CXCL13 and/or the chemokine receptor CXCR5. Another method comprises the step of administering to the subject a therapeutically effective amount of an expression vector that expresses an antibody to the chemokine CXCL13 and/or the chemokine receptor CXCR5.
    Type: Application
    Filed: September 29, 2011
    Publication date: May 24, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Rajesh SINGH, Shailesh SINGH
  • Patent number: 8177145
    Abstract: A feed injector system comprises a movable central member, a first member substantially concentric with the central member to define a first channel for conveying a first fluid oxidizer stream, a second member substantially concentric with the first member to define a second channel for conveying a fuel feed, and a third member substantially concentric with the second member to define a third channel for conveying a second fluid oxidizer steam. The first member and the second member are configured to enhance instability in the fuel feed emanating from the second channel.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: May 15, 2012
    Assignee: General Electric Company
    Inventors: Shailesh Singh Bhaisora, Dustin Wayne Davis, Ravindra Gopaldas Devi
  • Publication number: 20120100154
    Abstract: Methods for prevention or inhibition of the growth or metastasis of cancer cells in a subject are disclosed. One method comprises the step of administering to the subject a therapeutically effective amount of an antibody to the chemokine CCL25 and/or the chemokine receptor CCR9. Another method comprises the step of administering to the subject a therapeutically effective amount of an expression vector that expresses an antibody to the chemokine CCL25 and/or the chemokine receptor CCR9.
    Type: Application
    Filed: December 13, 2011
    Publication date: April 26, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Rajesh Singh, Shailesh Singh
  • Publication number: 20120100554
    Abstract: Methods for detecting cancer in a subject are disclosed. The method includes detecting the level of expression of one or more cancer markers in a biological sample obtained from the subject; and comparing the level of expression of the one or more cancer markers in the biological sample to a normal level of expression of the one or more cancer markers. The one or more cancer markers comprise CCL25 or CCR9 or both CCL25 and CCR9.
    Type: Application
    Filed: December 13, 2011
    Publication date: April 26, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, Rajesh Singh, Shailesh Singh
  • Publication number: 20120082993
    Abstract: Methods for detecting cancer or monitoring cancer progression in a subject are disclosed. The method includes detecting the level of expression of one or more cancer markers in a biological sample obtained from the subject; and comparing the level of expression of the one or more cancer markers in the biological sample to a normal level of expression of the one or more cancer markers. The one or more cancer markers comprises CXCL16 or CXCR6 or both CXCL16 and CXCR6. Also disclosed is a kit for detecting cancer or monitoring cancer progression.
    Type: Application
    Filed: December 6, 2011
    Publication date: April 5, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: JAMES W. LILLARD, SHAILESH SINGH, RAJESH SINGH
  • Publication number: 20120064089
    Abstract: Methods for prevention or inhibition of the growth or metastasis of cancer cells in a subject are disclosed. One method comprises the step of administering to the subject a therapeutically effective amount of an antibody to the chemokine CXCL16 and/or the chemokine receptor CXCR6. Another method comprises the step of administering to the subject a therapeutically effective amount of an expression vector that expresses an antibody to the chemokine CXCL16 and/or the chemokine receptor CXCR6.
    Type: Application
    Filed: September 15, 2011
    Publication date: March 15, 2012
    Applicant: Morehouse School of Medicine
    Inventors: James W. Lillard, Rajesh Singh, Shailesh Singh
  • Patent number: 8097250
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: January 17, 2012
    Assignee: Morehouse School of Medicine
    Inventors: James W. Lillard, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110287063
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Application
    Filed: May 10, 2011
    Publication date: November 24, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, JR., Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110280872
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110280871
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110206507
    Abstract: An air distribution system for manipulating a boundary layer of air across a wind turbine rotor blade. The wind turbine rotor blade includes at least one sidewall that defines a cavity therein. The sidewall extends between a leading edge and an axially-spaced trailing edge, and defines a chordwise axis between the leading edge and the trailing edge. The air distribution system includes a plurality of bleed flow assemblies that are positioned within the rotor blade and are configured to discharge air into the boundary layer to reduce a separation of the boundary layer from the rotor blade. Each bleed flow assembly of the plurality of bleed flow assemblies includes a bleed flow conduit that is coupled to an inner surface of the sidewall and is oriented with respect to the chordwise axis between the leading edge and the trailing edge. The bleed flow conduit is configured to channel air through the rotor blade.
    Type: Application
    Filed: January 4, 2011
    Publication date: August 25, 2011
    Inventors: Shailesh Singh Bhaisora, Narasimha Shastri, Anurag Gupta
  • Publication number: 20110150982
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Application
    Filed: January 26, 2011
    Publication date: June 23, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, Shailesh Singh, Jonathan K. Stiles
  • Patent number: 7964194
    Abstract: It is possible to inhibit inflammatory processes by administration of antibodies to chemokines. Identification of chemokines which are over-produced makes it possible to block specific chemokine activity using antibodies to the over-expressed chemokines.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: June 21, 2011
    Assignee: Morehouse School of Medicine
    Inventors: James W. Lillard, Jr., Udai P. Singh, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110123603
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Application
    Filed: January 26, 2011
    Publication date: May 26, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Shailesh Singh, Jonathan K. Stiles
  • Publication number: 20110091528
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Application
    Filed: December 14, 2010
    Publication date: April 21, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Shailesh Singh, Jonathan Stiles
  • Publication number: 20110091529
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Application
    Filed: December 15, 2010
    Publication date: April 21, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. Lillard, Shailesh Singh, Jonathan Stiles
  • Publication number: 20110081408
    Abstract: The present invention provides a means of inhibiting the growth and metastasis of cancer cells by administering anti-chemokine antibodies. It is possible to identify the particular chemokines which are over-expressed in the tumor using methods of the invention and administer antibodies against that over-expressed chemokine.
    Type: Application
    Filed: December 15, 2010
    Publication date: April 7, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: James W. LILLARD, Shailesh Singh, Jonathan Stiles