Patents by Inventor Shaimaa M. Badr-Eldin

Shaimaa M. Badr-Eldin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Surface-modified emulsomes for intranasal delivery of drugs
    Patent number: 11234933
    Abstract: Emulsome compositions comprising phosphatidylcholine, cholesterol, tristearin, and one or more lipophilic bioactive agents such as vinpocetine are provided. The emulsomes may further comprise surface modifications of either [N-(carbonyl-methoxypropylethyleneglycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt] (MPEG-DSPE) for peglyation or stearylamine for cationization. Methods of improving brain delivery of lipophilic bioactive agents by intranasally administering such emulsome compositions are also provided.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: February 1, 2022
    Assignee: KING ABDULAZIZ UNIVERSITY
    Inventors: Hibah M. Aldawsari, Shaimaa M. Badr-Eldin, Nourah Y. Assiri, Abdelsattar Omar
  • Instantly dissolving buccal films
    Patent number: 11147765
    Abstract: Instantly dissolving buccal fims comprising certain pH modifiers, film formers, film modifiers, and solubilizing agents are provided. Methods of providing the buccal film to enhance the dissolution and bioavailability of low solubility basic drugs, such as dapoxetine hydrochloride, in a subject are also provided.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: October 19, 2021
    Assignee: King Abdulaziz University
    Inventors: Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Abdelsattar Omar
  • Surface-modified emulsomes for intranasal delivery of drugs
    Patent number: 11058637
    Abstract: Emulsome compositions comprising phosphatidylcholine, cholesterol, tristearin, and one or more lipophilic bioactive agents such as vinpocetine are provided. The emulsomes may further comprise surface modifications of either [N-(carbonyl-methoxypropylethyleneglycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt] (MPEG-DSPE) for peglyation or stearylamine for cationization. Methods of improving brain delivery of lipophilic bioactive agents by intranasally administering such emulsome compositions are also provided.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: July 13, 2021
    Assignee: King Abdulaziz University
    Inventors: Hibah M. Aldawsari, Shaimaa M. Badr-Eldin, Nourah Y. Assiri, Abdelsattar Omar
  • Instantly dissolving buccal films
    Patent number: 10973760
    Abstract: Instantly dissolving buccal films comprising certain pH modifiers, film formers, film modifiers, and solubilizing agents are provided. Methods of providing the buccal film to enhance the dissolution and bioavailability of low solubility basic drugs, such as dapoxetine hydrochloride, in a subject are also provided.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: April 13, 2021
    Assignee: King Abdulaziz University
    Inventors: Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Abdelsattar Omar
  • Micellles containing alpha lipoic acid as a transdermal drug delivery system
    Patent number: 10799455
    Abstract: Micelle formulations comprising a tocopherol or derivative thereof, alpha lipoic acid, and a biologically active agent such as vinpocetine are provided. Films for transdermal delivery containing the micelle formulation and methods of treating cognitive and cerebrovascular disorders are also provided.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: October 13, 2020
    Assignee: King Abdulaziz University
    Inventors: Osama A. A. Ahmed, Khalid M. El-Say, Bader M. Aljaeid, Shaimaa M. Badr-Eldin, Tarek A. Ahmed
  • Development of an optimized avanafil-loaded invasomal transdermal film
    Patent number: 10751294
    Abstract: Nanosized avanafil (AVA) invasomes with enhanced transdermal delivery are provided. AVA invasomes were prepared with a vesicular size of 109.92 nm and an entrapment efficiency of 96.98%. The AVA invasomal film showed enhanced ex vivo permeation bioavailability compared to a raw AVA film.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: August 25, 2020
    Assignee: King Abdulaziz University
    Inventors: Osama A. A. Ahmed, Shaimaa M. Badr-Eldin