Patents by Inventor Shaina Brito

Shaina Brito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9220811
    Abstract: In various aspects, the present invention is directed to implantable neurostimulation leads and methods for their formation. In various additional aspects, the present invention is directed to medical devices having silicone-containing regions with overlying polymeric layers and to methods of forming the same.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: December 29, 2015
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Edward Holman Overstreet, Anne M. Pianca, Janusz A. Kuzman, Aditya Pandit, Shaina Brito, Robert E. Richard, Kerri DiPietro, Frederick H. Strickler, Mark Boden, Lan Pham, William Orinski
  • Patent number: 8901248
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 2, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Shaina Brito, Frederick Strickler
  • Patent number: 8338541
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: December 25, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Shaina Brito, Frederick Strickler
  • Publication number: 20110144276
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Application
    Filed: February 24, 2011
    Publication date: June 16, 2011
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Shaina Brito, Frederick H. Strickler
  • Patent number: 7914807
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: March 29, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Shaina Brito, Frederick H. Strickler
  • Publication number: 20080220041
    Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.
    Type: Application
    Filed: March 5, 2007
    Publication date: September 11, 2008
    Inventors: Shaina Brito, Frederick H. Strickler
  • Publication number: 20080057097
    Abstract: A medical device having a coating of cell adhesion polypeptides to enhance endothelial cell adhesion onto the medical device. The cell adhesion polypeptides may be any of the proteins of the extracellular matrix which are known to play a role in cell adhesion or derivative peptides such as RGD or YIGSR. The polypeptides may be incorporated into the backbone of a polymer such as polyurethane, or grafted onto a polymer such polybisphosphonate. The polypeptides may also be carried on antibodies or displayed on bacteriophages. The polypeptides may also be modified to have adhesive amino acid sequences. In certain embodiments, the medical device further comprises a temporary barrier that protects the polypeptides from biofouling. The temporary barrier may be formed of a biodegradable polymer and be constructed as a coating over the polypeptides or as a plurality of micelles encapsulating the polypeptides.
    Type: Application
    Filed: August 30, 2007
    Publication date: March 6, 2008
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: John Benco, Mark Boden, Shaina Brito, Wendy Naimark, Lan Pham
  • Publication number: 20070178165
    Abstract: A method is provided for making a parenteral dosage form of a pharmaceutical agent which includes (a) providing particles of a pharmaceutical agent; (b) blending the particles with particles of at least one bulking agent to form a first powder blend, which does not include a surfactant; (c) milling the first powder blend to form a milled blend which comprises microparticles or nanoparticles of the pharmaceutical agent; and (d) reconstituting the milled blend with a liquid vehicle, which includes at least one surfactant, for parenteral administration. A method also is provided which includes (a) providing particles of a pharmaceutical agent; (b) blending these particles with particles of an excipient to form a first blend; and (c) milling the first blend to form a milled blend that includes microparticles or nanoparticles, which exhibits a greater dispersibility, wettability, and suspendability as compared to the particles of step (a) or the first blend.
    Type: Application
    Filed: December 14, 2006
    Publication date: August 2, 2007
    Applicant: ACUSPHERE, INC.
    Inventors: David Altreuter, Howard Bernstein, Luis Brito, Shaina Brito, Olinda Carneiro, Donald Chickering, Eric Huang, Rajeev Jain, Sridhar Narasimhan, Namrata Pandit, Julie Straub
  • Publication number: 20070178166
    Abstract: Dry powder pharmaceutical formulations for pulmonary or nasal administration are made to provide an improved respired dose. These formulations may be blends of milled blends and may include a phospholipid, alone or in combination with other excipient materials. In one case, the process includes the steps of (a) providing particles which comprise a pharmaceutical agent, (b) blending the particles with particles of at least one first excipient to form a first powder blend; (c) milling the first powder blend to form a milled blend which comprises microparticles or nanoparticles of the pharmaceutical agent; and (d) blending the milled blend with particles of a second excipient to form a blended dry powder blend pharmaceutical formulation suitable for pulmonary or nasal administration.
    Type: Application
    Filed: December 14, 2006
    Publication date: August 2, 2007
    Applicant: ACUSPHERE, INC.
    Inventors: Howard Bernstein, Shaina Brito, Donald Chickering, Eric Huang, Rajeev Jain, Julie Straub
  • Publication number: 20070148211
    Abstract: A method is provided for making an oral dosage form of a pharmaceutical agent which includes the steps of (a) providing particles which include a pharmaceutical agent; (b) blending the particles with particles of a pre-processed excipient to form a primary blend, wherein the pre-processed excipient is prepared by (i) dissolving a bulking agent (e.g., a sugar) and at least one non-friable excipient (e.g., a waxy or liquid surfactant) in a solvent to form an excipient solution, and (ii) removing the solvent from the excipient solution to form the pre-processed excipient in dry powder form; (c) milling the primary blend to form a milled pharmaceutical formulation blend that includes microparticles or nanoparticles of the pharmaceutical agent; and (d) processing the milled pharmaceutical formulation blend into a solid oral dosage form or liquid suspension for oral administration. The process yields formulations having improved wettability or dispersibility.
    Type: Application
    Filed: December 14, 2006
    Publication date: June 28, 2007
    Applicant: Acusphere, Inc.
    Inventors: David Altreuter, Howard Bernstein, Luis Brito, Shaina Brito, Donald Chickering, Eric Huang, Rajeev Jain, Sridhar Narasimhan, Julie Straub