Patents by Inventor Shaina Brito
Shaina Brito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9220811Abstract: In various aspects, the present invention is directed to implantable neurostimulation leads and methods for their formation. In various additional aspects, the present invention is directed to medical devices having silicone-containing regions with overlying polymeric layers and to methods of forming the same.Type: GrantFiled: September 21, 2009Date of Patent: December 29, 2015Assignee: Boston Scientific Scimed, Inc.Inventors: Edward Holman Overstreet, Anne M. Pianca, Janusz A. Kuzman, Aditya Pandit, Shaina Brito, Robert E. Richard, Kerri DiPietro, Frederick H. Strickler, Mark Boden, Lan Pham, William Orinski
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Patent number: 8901248Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: GrantFiled: December 21, 2012Date of Patent: December 2, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: Shaina Brito, Frederick Strickler
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Patent number: 8338541Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: GrantFiled: February 24, 2011Date of Patent: December 25, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: Shaina Brito, Frederick Strickler
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Publication number: 20110144276Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: ApplicationFiled: February 24, 2011Publication date: June 16, 2011Applicant: Boston Scientific Scimed, Inc.Inventors: Shaina Brito, Frederick H. Strickler
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Patent number: 7914807Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: GrantFiled: March 5, 2007Date of Patent: March 29, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Shaina Brito, Frederick H. Strickler
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Publication number: 20080220041Abstract: In accordance with various aspects of the invention, implantable and insertable medical devices are provided, which contain one or more polymeric regions. In one aspect, the polymeric regions comprise (a) a block copolymer that comprises a polyaromatic block and a polyalkene block admixed with (b) a sulfonated high Tg polymer. In another aspect, the polymeric regions comprise a block copolymer that comprises (a) a sulfonated polymer block and (b) fluorinated polymer block.Type: ApplicationFiled: March 5, 2007Publication date: September 11, 2008Inventors: Shaina Brito, Frederick H. Strickler
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Publication number: 20080057097Abstract: A medical device having a coating of cell adhesion polypeptides to enhance endothelial cell adhesion onto the medical device. The cell adhesion polypeptides may be any of the proteins of the extracellular matrix which are known to play a role in cell adhesion or derivative peptides such as RGD or YIGSR. The polypeptides may be incorporated into the backbone of a polymer such as polyurethane, or grafted onto a polymer such polybisphosphonate. The polypeptides may also be carried on antibodies or displayed on bacteriophages. The polypeptides may also be modified to have adhesive amino acid sequences. In certain embodiments, the medical device further comprises a temporary barrier that protects the polypeptides from biofouling. The temporary barrier may be formed of a biodegradable polymer and be constructed as a coating over the polypeptides or as a plurality of micelles encapsulating the polypeptides.Type: ApplicationFiled: August 30, 2007Publication date: March 6, 2008Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: John Benco, Mark Boden, Shaina Brito, Wendy Naimark, Lan Pham
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Publication number: 20070178165Abstract: A method is provided for making a parenteral dosage form of a pharmaceutical agent which includes (a) providing particles of a pharmaceutical agent; (b) blending the particles with particles of at least one bulking agent to form a first powder blend, which does not include a surfactant; (c) milling the first powder blend to form a milled blend which comprises microparticles or nanoparticles of the pharmaceutical agent; and (d) reconstituting the milled blend with a liquid vehicle, which includes at least one surfactant, for parenteral administration. A method also is provided which includes (a) providing particles of a pharmaceutical agent; (b) blending these particles with particles of an excipient to form a first blend; and (c) milling the first blend to form a milled blend that includes microparticles or nanoparticles, which exhibits a greater dispersibility, wettability, and suspendability as compared to the particles of step (a) or the first blend.Type: ApplicationFiled: December 14, 2006Publication date: August 2, 2007Applicant: ACUSPHERE, INC.Inventors: David Altreuter, Howard Bernstein, Luis Brito, Shaina Brito, Olinda Carneiro, Donald Chickering, Eric Huang, Rajeev Jain, Sridhar Narasimhan, Namrata Pandit, Julie Straub
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Publication number: 20070178166Abstract: Dry powder pharmaceutical formulations for pulmonary or nasal administration are made to provide an improved respired dose. These formulations may be blends of milled blends and may include a phospholipid, alone or in combination with other excipient materials. In one case, the process includes the steps of (a) providing particles which comprise a pharmaceutical agent, (b) blending the particles with particles of at least one first excipient to form a first powder blend; (c) milling the first powder blend to form a milled blend which comprises microparticles or nanoparticles of the pharmaceutical agent; and (d) blending the milled blend with particles of a second excipient to form a blended dry powder blend pharmaceutical formulation suitable for pulmonary or nasal administration.Type: ApplicationFiled: December 14, 2006Publication date: August 2, 2007Applicant: ACUSPHERE, INC.Inventors: Howard Bernstein, Shaina Brito, Donald Chickering, Eric Huang, Rajeev Jain, Julie Straub
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Publication number: 20070148211Abstract: A method is provided for making an oral dosage form of a pharmaceutical agent which includes the steps of (a) providing particles which include a pharmaceutical agent; (b) blending the particles with particles of a pre-processed excipient to form a primary blend, wherein the pre-processed excipient is prepared by (i) dissolving a bulking agent (e.g., a sugar) and at least one non-friable excipient (e.g., a waxy or liquid surfactant) in a solvent to form an excipient solution, and (ii) removing the solvent from the excipient solution to form the pre-processed excipient in dry powder form; (c) milling the primary blend to form a milled pharmaceutical formulation blend that includes microparticles or nanoparticles of the pharmaceutical agent; and (d) processing the milled pharmaceutical formulation blend into a solid oral dosage form or liquid suspension for oral administration. The process yields formulations having improved wettability or dispersibility.Type: ApplicationFiled: December 14, 2006Publication date: June 28, 2007Applicant: Acusphere, Inc.Inventors: David Altreuter, Howard Bernstein, Luis Brito, Shaina Brito, Donald Chickering, Eric Huang, Rajeev Jain, Sridhar Narasimhan, Julie Straub