Patents by Inventor Shaji Daniel

Shaji Daniel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED CELLS SECRETING THERAPEUTIC ENZYMES
    Publication number: 20230174944
    Abstract: Provided herein are mammalian cells comprising a first exogenous nucleic acid encoding a DNAse protein and a second exogenous nucleic acid encoding another DNAse protein, such as DNASE1 protein and DNASE1L3 protein, that have improved properties, including the ability to degrades extracellular chromatin and remove Neutrophil Extracellular Traps (NETs). Use of these cells, including the use in the treatment of a subject in need thereof, is also contemplated.
    Type: Application
    Filed: April 15, 2021
    Publication date: June 8, 2023
    Applicant: Cartesian Therapeutics, Inc.
    Inventors: Yi Zhang, C. Andrew Stewart, Shaji Daniel, Metin Kurtoglu, Murat V. Kalayoglu