Patents by Inventor Shakeel MODAK

Shakeel MODAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF ENHANCING IMMUNOGENICITY OF POORLY IMMUNOGENIC ANTIGEN-SPECIFIC VACCINES USING ORAL YEAST BETA-GLUCANS
    Publication number: 20260174845
    Abstract: The present disclosure provides methods for enhancing the immunogenicity of a poorly immunogenic antigen-specific vaccine as well as methods for promoting diversification of the gut microbiome in a subject in need thereof comprising administering to the subject an effective amount of a beta-glucan extract derived from yeast. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: July 21, 2025
    Publication date: June 25, 2026
    Inventors: Nai-Kong CHEUNG, Shakeel MODAK, Govind RAGUPATHI
  • Anti-GD2 Administration Regimen
    Publication number: 20260159605
    Abstract: The present invention relates to the administration of GD2 binding antibodies associated with side-effects. In particular, the present invention concerns a method for reducing side-effects associated with the administration of a GD2 binding antibody.
    Type: Application
    Filed: December 8, 2022
    Publication date: June 11, 2026
    Inventors: Jaume MORA GRAUPERA, Nai-Kong CHEUNG, Shakeel MODAK, Vignesh RAJAH, Claus J. MØLLER SAN-PEDRO
  • Methods for treating neuroblastoma with combination therapy
    Patent number: 12435156
    Abstract: The present disclosure provides methods of treating neuroblastoma using an anti-GD2 antibody, at least one chemotherapeutic agent, and at least one hematopoietic growth factor. The present disclosure also provides compositions for treating neuroblastoma.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: October 7, 2025
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventor: Shakeel Modak
  • Methods of enhancing immunogenicity of poorly immunogenic antigen-specific vaccines using oral yeast beta-glucans
    Patent number: 12364752
    Abstract: The present disclosure provides methods for enhancing the immunogenicity of a poorly immunogenic antigen-specific vaccine as well as methods for promoting diversification of the gut microbiome in a subject in need thereof comprising administering to the subject an effective amount of a beta-glucan extract derived from yeast. Kits for use in practicing the methods are also provided.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: July 22, 2025
    Assignee: Memorial Sloan Kettering Cancer Center
    Inventors: Nai-Kong Cheung, Shakeel Modak, Govind Ragupathi
  • METHODS OF ENHANCING IMMUNOGENICITY OF POORLY IMMUNOGENIC ANTIGEN-SPECIFIC VACCINES USING ORAL YEAST BETA-GLUCANS
    Publication number: 20210236630
    Abstract: The present disclosure provides methods for enhancing the immunogenicity of a poorly immunogenic antigen-specific vaccine as well as methods for promoting diversification of the gut microbiome in a subject in need thereof comprising administering to the subject an effective amount of a beta-glucan extract derived from yeast. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: April 23, 2019
    Publication date: August 5, 2021
    Inventors: Nai-Kong CHEUNG, Shakeel MODAK, Govind RAGUPATHI
  • METHODS FOR TREATING NEUROBLASTOMA WITH COMBINATION THERAPY
    Publication number: 20210198379
    Abstract: The present disclosure provides methods of treating neuroblastoma using an anti-GD2 antibody, at least one chemotherapeutic agent, and at least one hematopoietic growth factor. The present disclosure also provides compositions for treating neuroblastoma.
    Type: Application
    Filed: February 22, 2021
    Publication date: July 1, 2021
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventor: Shakeel MODAK