Patents by Inventor Shaker Rashid

Shaker Rashid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single receptor assays for immunosuppressive drugs
    Patent number: 7642059
    Abstract: A highly specific homogeneous assay method for an immunosuppressive drug using an immunophilin in a single receptor format is provided. In the simplest format, a single receptor is utilized analogous to a competitive immunoassay whereby an immunophilin is substituted for an antibody, and a competition results between a drug conjugate and the drug analyte for a limited number of immunophilin binding sites. In a microparticle agglutination assay format, an immunophilin is either bound to a particle or in solution. In the case where an immunophilin is bound to a particle, a polyvalent conjugate of the drug analyte is present in solution.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: January 5, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Gerald Sigler, Mitali Ghoshal, Allan Dorn, Shaker Rashid
  • Mycophenolic acid immunogens and antibodies
    Publication number: 20090215993
    Abstract: Described are immunogenic compounds useful for generation of antibodies which are highly specific for mycophenolic acid which do not react or have substantially no cross-reactivity with the glucuronide metabolites of mycophenolic acid, especially the acyl-glucuronide metabolite.
    Type: Application
    Filed: October 24, 2008
    Publication date: August 27, 2009
    Inventors: Mitali Ghoshal, Raymond Hui, Shaker Rashid
  • HOMOGENEOUS DOUBLE RECEPTOR AGGLUTINATION ASSAY FOR IMMUNOSUPPRESSANT DRUGS
    Publication number: 20080081379
    Abstract: A homogeneous, non-competitive, double receptor agglutination assay for measuring immunosuppressant drugs is described. The assay employs at least two receptors wherein each receptor is specific for a separate binding site on the drug and wherein each receptor is bound to a detection particle. The immunosuppressant drug binds to the receptors and causes particle agglutination, which can be measured and correlated with the presence or amount of immunosuppressant drug in a sample.
    Type: Application
    Filed: July 3, 2007
    Publication date: April 3, 2008
    Inventors: Gerald F. Sigler, Mitali Ghoshal, Shaker Rashid, Yifei Wu, Allan R. Dorn, Jane S.C. Tsai
  • SINGLE RECEPTOR ASSAYS FOR IMMUNOSUPPRESSIVE DRUGS
    Publication number: 20070054338
    Abstract: A highly specific homogeneous assay method for an immunosuppressive drug using an immunophilin in a single receptor format is provided. In the simplest format, a single receptor is utilized analogous to a competitive immunoassay whereby an immunophilin is substituted for an antibody, and a competition results between a drug conjugate and the drug analyte for a limited number of immunophilin binding sites. In a microparticle agglutination assay format, an immunophilin is either bound to a particle or in solution. In the case where an immunophilin is bound to a particle, a polyvalent conjugate of the drug analyte is present in solution.
    Type: Application
    Filed: August 31, 2006
    Publication date: March 8, 2007
    Inventors: Gerald Sigler, Mitali Ghoshal, Allan Dorn, Shaker Rashid