Abstract: A turbine engine is provided. The turbine engine defines an axial direction and a radial direction, and includes: a rotor; a stator comprising a carrier; a seal assembly disposed between the rotor and the stator, the seal assembly defining a high-pressure side and a low-pressure side and comprising a plurality of seal segments, the plurality of seal segments including a seal segment having a seal face forming a fluid bearing with the rotor, a lip, and a body, the lip extending from the body along the axial direction of the turbine engine on the high-pressure side and including an outer pressurization surface along the radial direction of the turbine engine; and a seal support assembly, the seal support assembly comprising a spring arrangement extending between the carrier and the first seal segment to counter a pressure on the outer pressurization surface during operation of the turbine engine.

Abstract: Provided herein are methods, systems and digital microfluidic cartridges for the determination of ligand-target analyte affinity value (KD), determination of an association rate constant (kon), and/or determination of a dissociation rate constant (koff) in a PR (plasmon resonance) based system. More specifically, as described herein, the present disclosure is directed to improved methods, systems and digital microfluidic cartridges for determining a dissociation rate constant (koff) using free ligand molecules in the dissociation phase or dissociation step of a standard kinetic binding curve or in ligand-target analyte affinity analysis (referred to herein as ligand assisted dissociation (LAD)).

Abstract: In one embodiment, an illustrative method herein comprises: obtaining, by a process, a file having a given size; assigning, by the process, the file to a particular size-range bucket of a plurality of size-range buckets of a data ingestion pipeline, the plurality of size-range buckets having a corresponding size-based configuration; and forwarding, by the process, the file into a particular size-based service mesh ingress gateway of the data ingestion pipeline according to the particular size-range bucket to cause processing of the file within the data ingestion pipeline according to the corresponding size-based configuration of the particular size-range bucket.

Abstract: The present disclosure provides impedance-based detection of nucleic acids for screening of cancer. The present disclosure is based on the use of impedance spectroscopy to detect nucleic acids in solution in the clinical concentration range, without using any labels, amplification steps, bioreceptors, surface modification or complex electrode geometries. More particularly, the present disclosure leverages the structural variations in nucleic acids of healthy and cancer patients, to classify samples as cancer-positive or cancer-negative purely based on their electrophysiochemical properties. The present disclosure also provides a simple rapid, label-free miniaturized biosensor for detection and screening of cancer.

Abstract: Systems, methods, and storage media provided are useful in a computing environment receiving, modifying, and transforming service level information from database servers and entities in a hosted database environment. Multiple application programming interface (API) calls are made by a database observation system to request information for multiple service level indicators from database servers belonging to multiple different entities. Database observation system receives and aggregates the information for multiple service level indicators from each of the database servers belonging to multiple different entities. The database observation system provides, within a dashboard interface, the aggregated information for each of the multiple service level indicators, individual service level indicator scores, and aggregated service level indicator scores for each of the database servers for each of the multiple entities.

Abstract: Systems, methods, and storage media are provided that are useful in a computing environment for receiving, modifying, and transforming service level information from database servers and entities in a hosted database environment. Multiple application programming interface (API) calls are made by a database observation system to request information for multiple service level indicators from database servers belonging to multiple different entities. Database observation system receives and aggregates the information for multiple service level indicators from each of the database servers belonging to multiple different entities. The database observation system provides, within a dashboard interface, the aggregated information for each of the multiple service level indicators, individual service level indicator scores, and aggregated service level indicator scores for each of the database servers for each of the multiple entities.

Abstract: Systems, methods, and storage media are provided that are useful in a computing environment for receiving, modifying, and transforming service level information from database servers and entities in a hosted database environment. Multiple application programming interface (API) calls are made by a database observation system to request information for multiple service level indicators from database servers belonging to multiple different entities. Database observation system receives and aggregates the information for multiple service level indicators from each of the database servers belonging to multiple different entities. The database observation system provides, within a dashboard interface, the aggregated information for each of the multiple service level indicators, individual service level indicator scores, and aggregated service level indicator scores for each of the database servers for each of the multiple entities.

Abstract: A system to tokenize values may include a processing unit; a storage device comprising instructions, which when executed by the processing unit, configure the processing unit to: receive a data item with an original value from a first storage system; store the data item in a staging table; transform the original value of the data item in the staging table to a changed value based on a stored rule; store a mapping between the original value and the changed value in a library table; and transmit the library table to a second storage system configured to update a database table at the second storage system based on the library table.

Abstract: A transistor is provided that comprises a source region overlying a base structure, a drain region overlying the base structure, and a block of semiconducting material overlying the base structure and being disposed between the source region and the drain region. The block of semiconducting material comprises a gate controlled region adjacent the source region, and a drain access region disposed between the gate controlled region and the drain region. The drain access region is formed of a plurality of semiconducting material ridges spaced apart from one another by non-channel trench openings, wherein at least a portion of the non-channel trench openings being filled with a doped material to provide a depletion region to improve breakdown voltage of the transistor.

Abstract: The present subject matter describes system (100) for magnetic enrichment of magnetically marked analytes. The system has capture chip (102) comprising a sample chamber (104) for holding sample having magnetically marked analytes, and a recovery chamber (106) connected to the sample chamber by a channel (202). The volume of recovery chamber is smaller than volume of sample chamber (104). The system has magnetic arrangement (108) comprising a set of magnets (110) in which each two adjacent magnets have opposite polarities facing sample chamber. Set of magnets has dimensions that at least conform to coverage area of sample chamber. The magnetic arrangement also has at least one recovery magnet (112) having dimensions conforming to coverage area of recovery chamber and on alignment, the at least one recovery magnet (112) is at a distance farthest away from the recovery chamber. The system has a linear positioner (114) for moving the magnetic arrangement.

Abstract: The present invention relates to a membrane based assay method, device and kit for rapid detection and/or quantification of endotoxins in aqueous solutions and test samples. The kit as per the present invention comprises lipopolysaccharide (LPS) affinity ligand conjugated with gold nanoparticles (GNPs); a membrane device comprising an endotoxin affinity membrane positioned parallelly to one or more layer(s) of a hydrophilic material, which are optionally secured in an enclosure; and optionally comprising an indicator chart for quantification of endotoxins in the sample. The method comprises placing the sample suspected of endotoxin contamination on a surface of a membrane comprised in a membrane device; placing once or more a suspension of LPS-affinity ligand conjugated with GNPs over the same area as the sample placed and detecting the presence of endotoxin if the colour signal appears and based on its intensity quantifying the endotoxin levels.

Abstract: A method of forming an integrated circuit can include forming a heterostructure over a substrate structure, wherein the given substrate structure comprises a given semiconductor material. The method can include etching a castellated channel region in an e-mode device area of the heterostructure that defines a plurality of ridge channels interleaved between a plurality of trenches, the ridge channels comprising another semiconductor material. The method can also include forming an isolation region on the heterostructure to electrically isolate the e-mode device area from a d-mode device area of the heterostructure. The method can further include forming a mask with an opening that defines a castellated gate opening overlying the castellated channel region and the mask defines an opening overlaying a single planar gate overlying the d-mode device area of the heterostructure. The method can also include performing a contact fill with conductive material to form a castellated gate contact.

Abstract: A transistor is provided that comprises a source region overlying a base structure, a drain region overlying the base structure, and a block of semiconducting material overlying the base structure and being disposed between the source region and the drain region. The block of semiconducting material comprises a gate controlled region adjacent the source region, and a drain access region disposed between the gate controlled region and the drain region. The drain access region is formed of a plurality of semiconducting material ridges spaced apart from one another by non-channel trench openings, wherein at least a portion of the non-channel trench openings being filled with a doped material to provide a depletion region to improve breakdown voltage of the transistor.

Abstract: A system to tokenize values may include a processing unit; a storage device comprising instructions, which when executed by the processing unit, configure the processing unit to: receive a data item with an original value from a first storage system; store the data item in a staging table; transform the original value of the data item in the staging table to a changed value based on a stored rule; store a mapping between the original value and the changed value in a library table; and transmit the library table to a second storage system configured to update a database table at the second storage system based on the library table.

Abstract: A transistor is provided that comprises a source region overlying a base structure, a drain region overlying the base structure, and a block of semiconducting material overlying the base structure and being disposed between the source region and the drain region. The block of semiconducting material comprises a gate controlled region adjacent the source region, and a drain access region disposed between the gate controlled region and the drain region. The drain access region is formed of a plurality of semiconducting material ridges spaced apart from one another by non-channel trench openings, wherein at least a portion of the non-channel trench openings being filled with a doped material to provide a depletion region to improve breakdown voltage of the transistor.

Abstract: A transistor is provided that comprises a source region overlying a base structure, a drain region overlying the base structure, and a block of semiconducting material overlying the base structure and being disposed between the source region and the drain region. The block of semiconducting material comprises a gate controlled region adjacent the source region, and a drain access region disposed between the gate controlled region and the drain region. The drain access region is formed of a plurality of semiconducting material ridges spaced apart from one another by non-channel trench openings, wherein at least a portion of the non-channel trench openings being filled with a doped material to provide a depletion region to improve breakdown voltage of the transistor.

Abstract: The subject matter discloses systems and methods for magnetic capturing of rare cells from a liquid sample. The system includes a capture chip (104) having a longitudinal channel (208) comprising a first part (304) and a second part (306). The capture chip (104) has a capture well (302) near an end of the second part (306) closer to an interfacing region between the first part (304) and the second part (306). The system includes a first set (126) of multiple rows of magnets for the magnetic capturing of the rare cells in the first part (304) of the longitudinal channel (208), where a first row (132) of the first set (126) of multiple rows has magnets that span a length of the first part (304) of the longitudinal channel (208) and each subsequent row of the first set (126) of multiple rows has one magnet less than a previous row.

Abstract: A method of forming an integrated circuit can include forming a heterostructure over a substrate structure, wherein the given substrate structure comprises a given semiconductor material. The method can include etching a castellated channel region in an e-mode device area of the heterostructure that defines a plurality of ridge channels interleaved between a plurality of trenches, the ridge channels comprising another semiconductor material. The method can also include forming an isolation region on the heterostructure to electrically isolate the e-mode device area from a d-mode device area of the heterostructure. The method can further include forming a mask with an opening that defines a castellated gate opening overlying the castellated channel region and the mask defines an opening overlaying a single planar gate overlying the d-mode device area of the heterostructure. The method can also include performing a contact fill with conductive material to form a castellated gate contact.

Abstract: An apparatus and method for gesture detection and recognition. The apparatus includes a processing element, a radar sensor, a depth sensor, and an optical sensor. The radar sensor, the depth sensor, and the optical sensor are coupled to the processing element, and the radar sensor, the depth sensor, and the optical sensor are configured for short range gesture detection and recognition. The processing element is further configured to detect and recognize a hand gesture based on data acquired with the radar sensor, the depth sensor, and the optical sensor.

Abstract: An apparatus and method for radar based gesture detection. The apparatus includes a processing element and a transmitter configured to transmit radar signals. The transmitter is coupled to the processing element. The apparatus further includes a plurality of receivers configured to receive radar signal reflections, where the plurality of receivers is coupled to the processing element. The transmitter and plurality of receivers are configured for short range radar and the processing element is configured to detect a hand gesture based on the radar signal reflections received by the plurality of receivers.