Patents by Inventor Shalom Shabat

Shalom Shabat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline rosuvastatin calcium and compositions thereof for treatment of hyperlipidaemia
    Patent number: 7994178
    Abstract: The present invention provides a crystalline form of rosuvastatin calcium characterized by an X-ray powder diffraction pattern having peaks at about 4.7, 19.4 and 22.3° 2?±0.2° 2?. The crystalline form of the invention may be further characterized by a DSC thermogram with an endotherm at about 132° C. and another broad endotherm at about 220° C. to about 240° C., and a TGA thermogram showing a weight loss of about of 3 to about 5 percent up to about 100° C. The invention also provides a pharmaceutical composition comprising the crystalline rosuvastatin calcium, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: August 9, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Shlomit Wizel, Valerie Niddam-Hildesheim, Shalom Shabat
  • PROCESSES FOR PURIFYING VARENICLINE L-TARTRATE SALT AND PREPARING CRYSTALLINE FORMS OF VARENICLINE L-TARTRATE SALT
    Publication number: 20100010221
    Abstract: Processes for purifying Varenicline base or the L-tartrate salt thereof and for preparing Varenicline L-tartrate crystalline forms A and B are provided.
    Type: Application
    Filed: May 28, 2009
    Publication date: January 14, 2010
    Inventors: Revital Lifshitz-Liron, Shalom Shabat, Sharon Tomer, Yuriy Raizi, Eyal Gilboa, Pramod Kumar Pandey
  • Methods for the production of sildenafil base and citrate salt
    Patent number: 7618976
    Abstract: Provided are processes for the preparation of sildenafil base and the citrate salt of sildenafil. Also provided are sildenafil citrate water adduct and a method of preparing pharmaceutical compositions comprising combining the sildenafil citrate and/or sildenafil citrate water adduct with at least one pharmaceutically-acceptable excipient.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: November 17, 2009
    Assignee: Teva Pharmaceutical Industries Ltd
    Inventors: Viviana Braude, Judith Aronhime, Shalom Shabat
  • Rosuvastatin calcium with a low salt content
    Publication number: 20090240054
    Abstract: Provided is rosuvastatin calcium with a low salt by product content and processes for preparing such rosuvastatin calcium.
    Type: Application
    Filed: May 4, 2009
    Publication date: September 24, 2009
    Inventors: Valerie Niddam-Hildesheim, Shalom Shabat, Dalia Maidan-Hanoch
  • Rosuvastatin calcium with a low salt content
    Publication number: 20090215806
    Abstract: Provided is rosuvastatin calcium with a low salt by product content and processes for preparing such rosuvastatin calcium.
    Type: Application
    Filed: May 4, 2009
    Publication date: August 27, 2009
    Inventors: Valerie Niddam-Hildesheim, Shalom Shabat, Dalia Maidan-Hanoch
  • Crystalline rosuvastatin calcium
    Publication number: 20080176878
    Abstract: Provided is a crystalline form of rosuvastatin calcium characterized by X-ray powder diffraction peaks at about 4.7, 19.4 and 22.3° 2 theta±0.2° 2 theta and processes for the preparation thereof.
    Type: Application
    Filed: September 18, 2007
    Publication date: July 24, 2008
    Inventors: Shlomit Wizel, Valerie Niddam-Hildesheim, Shalom Shabat
  • Process for preparation of sertraline hydrochloride form I
    Publication number: 20080161412
    Abstract: Provided is a process for preparation of sertraline HCl Form I on an industrial scale.
    Type: Application
    Filed: January 16, 2008
    Publication date: July 3, 2008
    Inventors: Ronen Borochovitz, Shalom Shabat
  • Duloxetine HCL polymorphs
    Publication number: 20080027128
    Abstract: A crystalline form of duloxetine hydrochloride, pharmaceutical compositions of the crystalline form of duloxetine hydrochloride, and methods of preparing the crystalline form of duloxetine hydrochloride are provided.
    Type: Application
    Filed: May 23, 2007
    Publication date: January 31, 2008
    Inventors: Santiago Ini, Tamas Koltai, Shalom Shabat
  • Rosuvastatin calcium with a low salt content
    Publication number: 20070099994
    Abstract: Provided is rosuvastatin calcium with a low salt by product content and processes for preparing such rosuvastatin calcium.
    Type: Application
    Filed: August 16, 2006
    Publication date: May 3, 2007
    Inventors: Valerie Niddam-Hildesheim, Shalom Shabat, Dalia Maidan-Hanoch
  • Process for preparation of sertraline hydrochloride form I
    Publication number: 20070100165
    Abstract: Provided is a process for preparation of sertraline HCl Form I on an industrial scale.
    Type: Application
    Filed: June 9, 2006
    Publication date: May 3, 2007
    Inventors: Ronen Borochovitz, Shalom Shabat
  • Preparation of rosuvastatin
    Publication number: 20070037979
    Abstract: Provided are processes for preparing intermediates of rosuvastatin and their use in preparation of rosuvastatin and rosuvastatin salts thereof.
    Type: Application
    Filed: February 22, 2006
    Publication date: February 15, 2007
    Inventors: Valerie Niddam-Hildesheim, Anna Balanov, Natalia Shenkar, Shalom Shabat, Dalia Maidan-Hanoch
  • Process for preparing losartan potassium with improved flowability
    Publication number: 20060241161
    Abstract: Provided is a method of improving the flowability of losartan potassium powder having an initial Hausner ratio of 1.45 or more, which method includes reslurrying the losatrtan potassium in a reslurry solvent.
    Type: Application
    Filed: April 13, 2006
    Publication date: October 26, 2006
    Inventors: Igor Lifshitz, Ilan Kor, Shalom Shabat
  • Methods for the production of sildenafil base and citrate salt
    Publication number: 20050182066
    Abstract: Provided are processes for the preparation of sildenafil base and the citrate salt of sildenafil. Also provided are sildenafil citrate water adduct and a method of preparing pharmaceutical compositions comprising combining the sildenafil citrate and/or sildenafil citrate water adduct with at least one pharmaceutically-acceptable excipient.
    Type: Application
    Filed: January 5, 2005
    Publication date: August 18, 2005
    Inventors: Viviana Braude, Judith Aronhime, Shalom Shabat
  • Process for preparing losartan potassium with improved flow ability
    Publication number: 20040171843
    Abstract: Provided is a method of improving the flowability of losartan potassium powder having an initial Hausner ratio of 1.45 or more, which method includes reslurrying the losatrtan potassium in a reslurry solvent.
    Type: Application
    Filed: October 17, 2003
    Publication date: September 2, 2004
    Inventors: Igor Lifshitz, Ilan Kor, Shalom Shabat