Abstract: Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises a unique peptide having 31 amino acids and another unique peptide having 21 amino acids and connected with an oligo-nucleotide through a diphosphodiester or diphosphodithioate ester linkage. The composition has a light absorption spectrum with typical absorption ratios of 1.998 at 260 nm/280 nm and 1.359 at 260 nm/230 nm.

Abstract: An assay method for determining the effect of Product R on virus infection of Hela cells. The method comprising the following step: (1) dividing Hela cells into several groups, (2) treating one group with Product R prior to infecting the cells with a virus and treating another group with Product R after the cells being infected with the virus, and (3) determining the effects of Product R on virus infection by comparing the changes in the cell cycle, DNA fragmentation and p53 protein in cells undergone the different treatments in step (2).

Abstract: The present invention discloses a method for treating patients having melanoma or melanoma associated symptoms by parenterally administering Product R, a peptide-nucleic acid preparation.

Abstract: The invention relates to a method of inhibiting adenovirus replication. The method comprises the step of contacting Product R with cells that are infected with adenovirus. The invention provides a basis for the treatment of adenovirus infections in human such as pink eye disease.

Abstract: A method of treating patients having viral infections including herpes simplex virus 1 and 2 infections and human papillomavirus infections by topically administering Product R, a peptide-nucleic acid preparation, by itself or in a composition comprising Product R and other pharmaceutically acceptable carriers for topical administration, is disclosed.

Abstract: A method of treating patients having rheumatoid arthritis by administering Product R, a peptide-nucleic acid preparation, is disclosed.

Abstract: Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises a unique peptide having 31 amino acids and another unique peptide having 21 amino acids and connected with an oligo-nucleotide through a diphosphodiester or diphosphodithioate ester linkage. The composition has a light absorption spectrum with typical absorption ratios of 1.998 at 260 nm/280 nm and 1.359 at 260 nm/230 nm.

Abstract: The down-regulation of the expression of the HIV coreceptor, CCR5 in H9 lymphoma or U937 promonocyte cells by Product R, a peptide-nucleotide preparation, is determined by a method comprising the steps of cell culture, electroporation, reverse transcription-polymerase chain reaction and electrophoresis.

Abstract: The present invention discloses a method of treatment for patients having lesions resulting from papillomavirus infections by topically administering Product R, a peptide-nucleic acid preparation, to the lesions.

Abstract: Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises nucleotides and peptides that have molecular weights not more than 14 KDa and substantially not more than 8 KDa. The composition has a light absorption spectrum with typical absorption ratios of 1.998 at 260 nm/280 nm and 1.359 at 260 nm/230 nm.

Abstract: The present invention discloses a treatment for patients with the B19 parvovirus associated symptoms or patients carrying or infected by the B19 parvovirus or having antibodies against the B19 parvovirus using Product R, a peptide-nucleic acid preparation.

Abstract: The present invention discloses a method for treating patients having the FIV associated symptoms or patients carrying or infected by the FIV or having antibodies against the FIV is disclosed using Product R, a peptide-nucleic acid preparation.

Abstract: A method of treating patients having suppressed immune systems by perenterally administering Product R, a peptide-nucleic acid preparation, alone or in a combination with one or more immuno-modulators, is disclosed.

Abstract: The present invention discloses a method of treating patients having AIDS or HIV infections by parenterally administering Product R, a peptide-nucleic acid preparation, in a combination with one or more antiviral agents useful for treating AIDS or HIV infections including HIV protease inhibitors and nucleoside analogs.

Abstract: The present invention discloses a method for treating anemia by stimulating red blood cells production by administering parenterally Product R, a peptide-nucleic acid preparation.

Abstract: The present invention discloses a method for treating patients having the CDV associated symptoms or animals carrying or infected by the canine distemper virus (CDV) or having antibodies against the CDV using Product R, a peptide-nucleic acid preparation.

Abstract: Methods of making feminine hygienic pads from non-layered and layered material by use of folding, pressure molding and various methods of bonding to create a long geometric form with an anterior leading panel of narrow thickness and a thicker posterior underpanel of a wider thickness. The folded panels may be bonded by either a suitable adhesive, crimping, heat, pressure or ultrasonic means leaving an anterior portion with a leading anterior edge and a larger posterior portion. A filler may be inserted between the folds of the material prior to bonding. Thereafter, the long geometric form is multiple cut transversely providing pads about two inches long. These pads are used for insertion into the female interlabial space. The geometric configuration of the pads facilitates insertion of the pad via the anterior leading edge into the interlabial space and has improved retention within such space.

Abstract: Feminine Hygienic Pads with improved absorption properties for use in the interlabial space in the area of the female urethral meatus and vaginal meatus for absorbing urine and other undesirable exudations comprising an elongated fibrous pad base of cylindrical, elliptical, polygonal or similar regular shape, the surface of the pad base being formed with multiple flutings, a multiplicity of absorptive cells or pin-cushioning or being formed wholly or in part of shaggy material to increase the absorptive surface area of the pad.

Abstract: Methods of making feminine hygienic pads from non-layered and layered material by use of folding to make predetermined multiple folds in said material, said folding may be with a device attached to a sewing machine for stitching said pads longitudinally adjacent a longitudinal leading edge creating an anterior narrow leading panel of narrow thickness and a posterior under panel of a wider thickness providing a long geometric form. Thereafter the said long geometric form is multiple cut providing pads of about two inches long. In some pads having fillers, the filler material is laid between the folds of the layered or non-layered material prior to stitching and after the long geometric form is produced, it is cut into desired lengths about two inches long providing the pads. These pads are for insertion into the interlabial space and have a geometric configuration which facilitates insertion of the pad into the interlabial space and has improved retention within such space.

Abstract: Methods of making feminine hygienic pads from non-layered and layered material by use of folding to make predetermined multiple folds in said material, said folding may be with a device attached to a sewing machine for stitching said pads longitudinally adjacent a longitudinal leading edge creating an anterior narrow leading panel of narrow thickness and a posterior under panel of a wider thickness providing a long geometric form. Thereafter the said long geometric form is multiple cut providing pads of about two inches long. In some pads having fillers, the filler material is laid between the folds of the layered or non-layered material prior to stitching and after the long geometric form is produced, it is cut into desired lengths about two inches long providing the pads. These pads are for insertion into the interlabial space and have a geometric configuration which facilitates insertion of the pad into the interlabial space and has improved retention within such space.