Patents by Inventor Shan Cao

Shan Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124853
    Abstract: Provided are transaminase mutants and uses thereof. The transaminase mutant is obtained by one or more amino acid mutations occurring in SEQ ID NO: 2 or is a mutant with a conserved amino acid mutation obtained by taking the sequence SEQ ID NO: 1 of a wild-type CvTA transaminase as a reference. Compared with wild-type transaminases, the catalytic activity of the mutant is improved to different degrees, so that the production efficiency of chiral amine compound synthesis may be improved.
    Type: Application
    Filed: July 6, 2021
    Publication date: April 18, 2024
    Inventors: Hao Hong, Gage James, Yi Xiao, Na Zhang, Xuecheng Jiao, Yulei Ma, Huiyan Mou, Zujian Wang, Kaihua Sun, Xiang Li, Tong Zhao, Shan Cao
  • Publication number: 20240010997
    Abstract: Provided are a cytochrome P450 enzyme mutant and an application thereof. The enzyme activity and anti-Markov oxidation selectivity of P450 derived from a wild-type strain of Bacillus megaterium undergo protein modification by means of directed evolution, thus improving enzyme activity and selectivity, and developing a series of P450 enzyme mutants that may be used for industrial production.
    Type: Application
    Filed: April 25, 2021
    Publication date: January 11, 2024
    Inventors: Hao HONG, Gage JAMES, Na ZHANG, Xuecheng JIAO, Yulei MA, Shan CAO, Yibing CHENG, Kaihua SUN
  • Publication number: 20230235300
    Abstract: Provided are a transaminase mutant and an application thereof. Compared with an amino acid sequence shown in SEQ ID NO:1, an amino acid sequence of the transaminase mutant includes at least one of the following mutation sites: L166, K149, K146, A168, H73, F133, H82, E24, V194, T294, A295, G235 and F236. The mutant of the present invention has the improved catalytic activity for a transammonization reaction of ketone substrates, and is suitable for industrial production of chiral amines.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 27, 2023
    Inventors: Hao HONG, Gage JAMES, Yi XIAO, Na ZHANG, Xuecheng JIAO, Yulei MA, Huiyan MU, Shan CAO
  • Publication number: 20230227797
    Abstract: Provided are a transaminase mutant and use thereof. The transaminase mutant has an amino acid sequence obtained by mutation of an amino acid sequence shown in SEQ ID NO:1, the mutation at least includes one of the following mutation site combinations: T7C+S47C, Q78C+A330C, V137C+G313C, A217C+Y252C and L295C+C328C; or the transaminase mutant has an amino acid sequence which has the mutation sites in the mutated amino acid sequence and has 80% or more identity with the mutated amino acid sequence. The transaminase mutant realizes the change of protein structure and functions, reduces the enzyme amount, increases the enantiomeric excess (ee) value of a product, and reduces the difficulty of post-processing, so that the transaminase mutant may be suitable for industrial production.
    Type: Application
    Filed: October 28, 2019
    Publication date: July 20, 2023
    Inventors: Hao HONG, Gage JAMES, Yi XIAO, Yulei MA, Na ZHANG, Xuecheng JIAO, Huiyan MU, Yibing CHENG, Shan CAO
  • Patent number: 10571627
    Abstract: An optical fiber comprises, from a center to a periphery, a fiber core of undoped silica; a cladding layer; and a coating of polyacrylate, wherein the fiber core has a radius of 5 to 7 ?m and an ellipticity of less than 1.5%, the cladding layer with an ellipticity of less than 0.4% comprises inner, intermediate, and outer cladding layers, the inner cladding layer being doped with fluorine of 5 to 12 ?m thickness, and refractive index difference to fiber core of ?0.4 to ?0.2%, the outer cladding layer being undoped quartz of 25 to 45 ?m thickness, and the coating comprises an inner coating of 25 to 40 ?m thickness, and an outer coating of 25 to 35 ?m thickness and an ellipticity of less than 2%. The optical fiber has high durability and large effective transmission area, a method and system for preparing such optical fiber are also disclosed.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: February 25, 2020
    Assignees: ZHONGTIAN TECHNOLOGY FIBER POTICS CO., LTD, ZHONGTIAN TECHNOLOGY ADVANCED MATERIALS CO., LTD., JIANGSU ZHONGTIAN TECHNOLOGY CO., LTD.
    Inventors: Shan-Shan Cao, Zhi-Zhong Liu, Yi-Chun Shen, Xiao-Xing Zhu, Zhen Wang, Hai-Tao Zhang, Hai-Tao Xu, Ji-Gang Hu, Hai-Yan Su
  • Publication number: 20190101693
    Abstract: An optical fiber comprises, from a center to a periphery, a fiber core of undoped silica; a cladding layer; and a coating of polyacrylate, wherein the fiber core has a radius of 5 to 7 ?m and an ellipticity of less than 1.5%, the cladding layer with an ellipticity of less than 0.4% comprises inner, intermediate, and outer cladding layers, the inner cladding layer being doped with fluorine of 5 to 12 ?m thickness, and refractive index difference to fiber core of ?0.4 to ?0.2%, the outer cladding layer being undoped quartz of 25 to 45 ?m thickness, and the coating comprises an inner coating of 25 to 40 ?m thickness, and an outer coating of 25 to 35 ?m thickness and an ellipticity of less than 2%. The optical fiber has high durability and large effective transmission area, a method and system for preparing such optical fiber are also disclosed.
    Type: Application
    Filed: November 30, 2018
    Publication date: April 4, 2019
    Inventors: SHAN-SHAN CAO, ZHI-ZHONG LIU, YI-CHUN SHEN, XIAO-XING ZHU, ZHEN WANG, HAI-TAO ZHANG, HAI-TAO XU, JI-GANG HU, HAI-YAN SU
  • Publication number: 20160224339
    Abstract: A program converting system is provided. The system is running on a comparator. The program converting system includes a program importing module, a program converting module, a characteristic parameters fetching module and a storage module. The program importing module is used to import a program data package containing a first measurement program and characteristic parameters of at least one sample. The program converting module is used to convert the first measurement program to a second measurement program suitable for a comparator. The characteristic parameters fetching module is used to fetch the characteristic parameters from the program data package. The storage module is used to store the second measurement program and the characteristic parameter in a storage unit of the comparator. A method for program converting is also provided.
    Type: Application
    Filed: April 30, 2015
    Publication date: August 4, 2016
    Inventors: ZI ZHANG, WEI XU, MING-SHAN CAO, KUEI-YANG LIN
  • Patent number: 8954937
    Abstract: An image detection program creating system comprise a parameter setting module, an image loading module, a programming module, and a program conversion module. The parameter setting module sets parameters of a Dimensional Measuring Interface Specification (DMIS). The image loading module loads a 3D image. The programming module programs the DMIS program according to the parameters of the DMIS and the 3D image. The program conversion module converts the compiled DMIS into an image detection program.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: February 10, 2015
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Ming-Shan Cao, Kuei-Yang Lin, Wei Xu, Yuan-Ke Li
  • Publication number: 20140355009
    Abstract: A measuring apparatus includes a supporting column, a securing assembly, and a pair of measuring elements. The securing assembly is movably located on the supporting column at a predetermined height. The pair of measuring elements is secured on the securing assembly opposite to each other. The measuring elements receive a workpiece and transmit lasers to the workpiece respectively.
    Type: Application
    Filed: January 16, 2014
    Publication date: December 4, 2014
    Applicants: HON HAI PRECISION INDUSTRY CO., LTD., HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD.
    Inventors: KUEI-YANG LIN, MING-SHAN CAO, FAN-JIAN ZENG, BAO-FENG QU
  • Patent number: 8636377
    Abstract: A light tube holder includes a base and two connectors for receiving either a light-emitting diode (LED) tube or a fluorescent tube. The connector includes a rotary member rotatably received in a through hole defined in a retainer, and three conductive elastic pieces positioned in the retainer around the through hole. One elastic piece is electrically connected to an LED tube drive circuit board, and the other two elastic piece are electrically connected to a fluorescent tube drive circuit board. The rotary member can be rotated to first and second positions, wherein at the first position, the LED tube can be activated, and at the second position the fluorescent tube can be activated.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: January 28, 2014
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd, Hon Hai Precision Industry Co., Ltd.
    Inventors: Qing-Shan Cao, Jian-Pu Chen, Yu Hu
  • Patent number: 8604715
    Abstract: A lamp tube switch circuit includes a first connector and a second connector for connecting a lamp tube, a power supply, a switch module including at least six switches connected between the power port, the first connector and second connector, a detecting unit connected between the first connector and the second connector, a control unit, a ballast and a starter. The detecting unit detects impedances between the pins of the lamp tube to determine the type of the lamp tube. The control unit is connected to the detecting unit, and operated to have some of the switches to turn one and the others to turn off whereby a drive circuit is formed enabling power from the power supply to flow through the lamp tube to make the lamp tube to generate light.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: December 10, 2013
    Assignees: Hong Fu Jin Precision (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Qing-Shan Cao, Zheng-Nian Liu, Yu Hu, Jian-Pu Chen
  • Patent number: 8604721
    Abstract: A lamp tube switching circuit includes a first connector and a second connector for connecting either an LED lamp tube or a fluorescent type lamp tube, a switch module being a mechanical switch including first, second and third switches, a starter and ballast. Each of the first and second switches has a static terminal for connecting with a power supply, and four dynamic terminals for selectively connecting with the static terminal thereof. Different circuits can be configured by adjusting the connection between the static and dynamic terminals, wherein each circuit can drive a selected type of lamp tube to generate light.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: December 10, 2013
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Qing-Shan Cao, Zheng-Nian Liu, Nan Zeng, Miao-Ping Guo
  • Patent number: 8604706
    Abstract: A lamp tube switch circuit supplies power to a selected LED/fluorescent lamp tube connected between first and second connectors and comprises a ballast and a starter. A power supply has positive and negative terminals. A switch module comprises first, second and third switches each having a first end connecting with the positive terminal, fourth and fifth switches each having a first end connecting with the negative terminal and a sixth switch having a first end connecting with the first connector. A button module has six buttons one of which is correspondent to the selected lamp tube. A control unit is connected to the button module, and functions to turn on and turn off the switches with a predetermined mode according the selected lamp tube.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: December 10, 2013
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Qing-Shan Cao, Zheng-Nian Liu, Lin-Shu Zhou, Ye-La An
  • Patent number: 8561340
    Abstract: An illumination device includes a tube holder including two connectors for receiving either a light-emitting diode (LED) tube and or a fluorescent tube. One of the connectors includes a rotary member rotatably received in a through hole defined in a retainer, and three conductive elastic pieces positioned in the retainer around the through hole. One elastic piece is electrically connected to an LED tube drive circuit board and a fluorescent tube drive circuit board, and the other two conductive pieces are electrically connected to the LED and the fluorescent tube drive circuit boards, respectively. The rotary member can be rotated to first and second positions, wherein at the first position, the LED tube can be activated, and at the second position the fluorescent tube can be activated.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: October 22, 2013
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Qing-Shan Cao, Zheng-Nian Liu, Yu Hu, Jun-Ping Liu
  • Publication number: 20130254753
    Abstract: An image detection program creating system comprise a parameter setting module, an image loading module, a programming module, and a program conversion module. The parameter setting module sets parameters of a Dimensional Measuring Interface Specification (DMIS). The image loading module loads a 3D image. The programming module programs the DMIS program according to the parameters of the DMIS and the 3D image. The program conversion module converts the compiled DMIS into an image detection program.
    Type: Application
    Filed: November 30, 2012
    Publication date: September 26, 2013
    Applicants: HON HAI PRECISION INDUSTRY CO., LTD., HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD.
    Inventors: MING-SHAN CAO, KUEI-YANG LIN, WEI XU, YUAN-KE LI
  • Patent number: 8523405
    Abstract: An LED illuminating device comprises a housing with a base plate, a prism sheet and a circuit board. The prism sheet is mounted in the housing and comprises a number of V-shaped micro-grooves formed thereon along three directions intersecting with each other. The circuit board is fixed on the base plate, wherein a plurality of LED units are arranged on the circuit board, each two adjacent LED units are spaced a preset distance apart from each other and emit light of different colors. Six virtual mixed light sources are formed by reflection of the prism sheet to the circuit board when the light emitted by an LED unit mixes with light emitted from adjacent LED units on the circuit board. Each of the virtual mixed light sources has a color different from the colors of the light emitted from the LED units.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: September 3, 2013
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Shao-Han Chang, Qing-Shan Cao, Su-Tzong Liu
  • Patent number: 8459829
    Abstract: An illuminating system includes a universal lamp holder. The universal lamp holder includes a switch unit, a starter, a ballast, a first socket and a second socket. The ballast is connected to the voltage-input terminal and the first socket. The starter is connected to the first socket and the switch unit. The second socket is connected to the switch unit and the voltage-output terminal, and the switch unit is configured for selectively connecting the second socket to the voltage-input terminal or connecting the second socket to the starter. When the second socket is switched to connect to the voltage-input terminal, the illuminating system is switched to an LED lamp mode, and when the second socket is switched to be connected to the starter, the illuminating system is switched to a fluorescent lamp mode.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: June 11, 2013
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Qing-Shan Cao, Sheng-Peng Tseng
  • Patent number: 8408750
    Abstract: An LED illuminating device includes a hollow base including a first end and a second end, an LED substrate, a connector, and a driving circuit module accommodated in the base. A plurality of vents are defined in a circumferential wall of the hollow base; a space is formed between a circumferential wall of the driving circuit module and the inner surface of the circumferential wall of the hollow base. The space can communicate with the plurality of vents and serve as a hot air channel, to promote heat exchange between hot air in the base and cool air outside the base.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: April 2, 2013
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Shao-Han Chang, Fu-Qiu Shi, Qing-Shan Cao
  • Patent number: 8403692
    Abstract: An illumination device includes a light tube holder including two connectors for receiving either a light-emitting diode (LED) tube or a fluorescent tube. One of the connectors includes a rotary member rotatably received in a through hole defined in a retainer, and four conductive elastic pieces positioned in the retainer around the through hole. Two of the conductive pieces are electrically connected to an LED tube drive circuit board and the other two are connected to a fluorescent tube drive circuit board. The rotary member can be rotated to first and second positions, wherein at the first position, the LED tube can be activated, and at the second position the fluorescent tube can be activated.
    Type: Grant
    Filed: November 22, 2011
    Date of Patent: March 26, 2013
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Qing-Shan Cao, Yu Hu, Zheng-Nian Liu, Miao-Ping Guo
  • Patent number: D980553
    Type: Grant
    Filed: March 3, 2022
    Date of Patent: March 7, 2023
    Assignee: SHENZHEN JIANFENG DECORATION DESIGN ENGINEERING CO., LTD
    Inventor: Shan Cao