Abstract: Disclosed are formulations, including both liquid and lyophilized formulations, comprising a benzodiazepine antibody-drug conjugate (ADC) and a cyclodextrin. Also disclosed are methods of purifying mixtures comprising benzodiazepine antibody-drug conjugates and process drug-related impurities.

Abstract: A method for treating fatty liver disease in a patient in need thereof, including a step of administering an effective amount of zoledronic acid. The fatty liver disease includes fatty liver disease caused by foodborne and hereditary factors, in particular non-alcoholic fatty liver. A dosage form of the zoledronic acid is an injection, a solution, a tablet, or a capsule.

Abstract: Methods for etching a hardmask layer to transfer features into a material layer using an etch process are provided. The methods described herein advantageously facilitate profile and dimension control of features through a proper sidewall and bottom management scheme during the hardmask open process. In one embodiment, a method for etching a hardmask layer to form features in the hardmask layer includes supplying an etching gas mixture onto a substrate to etch an exposed portion of a hardmask layer exposed by a patterned photoresist layer disposed on the substrate, switching the etching gas mixture to a deposition gas mixture comprising a silicon containing gas to form a passivation layer on sidewalls of the hardmask layer and forming openings in the hardmask layer.

Abstract: An information processing device includes: a memory configured to store data illustrating a three-dimensional model reproducing an environment of a work site; and a processor coupled to the memory and configured to specify a first partial region in which a work target is present from the three-dimensional model based on a detection result of an orientation of a work operator present at the work site, specify a second partial region corresponding to the work target from the first partial region based on at least one of a geometric shape of the first partial region and color information of the first partial region, and register, in the memory, three-dimensional coordinates of the second partial region in a coordinate space in which the three-dimensional model is formed as position information for displaying, according to a position of the work target, image information on an image in which the work site is photographed.

Abstract: An information processing device includes: a memory; and a processor coupled to the memory and configured to execute reception processing that includes receiving event information from a plurality of terminal devices, execute conversion processing that includes converting the event information received in a predetermined time period to a multitouch event in a format describing a plurality of touch events that occur at the same time; and execute notification processing that includes notifying a target application of the multitouch event via an operating system.

Abstract: A method of removing a metal-containing layer (e.g., tungsten) from a substrate is provided. The method includes generating a first plasma in a process volume of a plasma chamber when a patterned device is disposed on a substrate support in the process volume. The patterned device includes a patterned region and an unpatterned region; a substrate; a tungsten-containing layer formed over the substrate; a supporting layer disposed between the tungsten-containing layer and the substrate. The patterned region includes exposed surfaces of the supporting layer and the unpatterned region does not include any exposed surfaces of the supporting layer. The method further includes depositing a first film over the patterned region of the tungsten-containing layer with the first plasma; and removing portions of the unpatterned region of the tungsten-containing layer with the first plasma without depositing the first film over the unpatterned region.

Abstract: Techniques are described for allowing a user to define hierarchical relationships for a multidimensional data model without assistance from a data administrator. The hierarchical relationships can be stored as on the client device as part of report metadata so that they are customizable by the client. A graphical user interface is also described for generating reports using a reporting tool. Through move and select operations, a report along with its underlying hierarchical relationships can be customized by the client.

Abstract: Disclosed are formulations, including both liquid and lyophilized formulations, comprising a benzodiazepine antibody-drug conjugate (ADC) and a cyclodextrin. Also disclosed are methods of purifying mixtures comprising benzodiazepine antibody-drug conjugates and process drug-related impurities.

Abstract: An information providing method includes: measuring a static object three-dimensionally in an environment, by a processor; sequentially measuring a position of a dynamic object in the environment, by the processor; transmitting measurement data of the static object measured to a predetermined information processing apparatus through a communication network; transmitting measurement data of the dynamic object measured to the information processing apparatus through a communication network; receiving support data rem the information processing apparatus based on an environment grasping image that is generated from the measurement data, of the static object and the measurement data of the dynamic object by the information processing apparatus; and presenting the received support data to the environment at predetermined timing, by the processor.

Abstract: A method of etching a hardmask layer formed on a substrate is provided. The method includes supplying an etching gas mixture to a processing region of a processing chamber. A device substrate is disposed in the processing region when the etching gas mixture is supplied to the processing region. The device substrate comprises a substrate and a hardmask layer formed over the substrate. The etching gas mixture comprises a fluorine-containing gas, a silicon-containing gas, and an oxygen-containing gas. The method further includes providing RF power to the etching gas mixture to form a plasma in the processing region. The plasma is configured to etch exposed portions of the hardmask layer.

Abstract: A method for treating fatty liver disease in a patient in need thereof, including a step of administering an effective amount of zoledronic acid. The fatty liver disease includes fatty liver disease caused by foodborne and hereditary factors, in particular non-alcoholic fatty liver. A dosage form of the zoledronic acid is an injection, a solution, a tablet, or a capsule.

Abstract: An operation support method is disclosed. A three dimensional panorama image is generated by overlapping multiple images with each other based on posture information of a camera and a feature point map of the multiple images captured by the camera. The three dimensional panorama image is displayed at a first display device. At a second display device, position information of a target indicated is output based on current posture information of the camera in response to an indication of the target on the three dimensional panorama image.

Abstract: Porous organic compositions including a core comprising nitrogen-containing molecules and a shell comprising nitrogen-containing compounds wherein the shell is non-chemically bonded to the core are provided herein. Processes for making the porous organic compositions as well as gas separation processes using the porous organic compositions are also provided herein.

Abstract: Disclosed are formulations, including both liquid and lyophilized formulations, comprising a benzodiazepine antibody-drug conjugate (ADC) and a cyclodextrin. Also disclosed are methods of purifying mixtures comprising benzodiazepine antibody-drug conjugates and process drug-related impurities.

Abstract: A conference system includes at least one server and at least one mobile terminal connectable to the server. The mobile terminal includes an orientation estimation unit configured to detect orientation information of the mobile terminal, an operation unit configured to detect operation information of an operation performed; and an event transmission unit configured to transmit the orientation information and the operation information. The server includes an image information generation unit configured to generate image information of a conference material and image information of a pointer drawn over the image information of the conference material based on the drawing event, and an action information generation unit configured to generate action information corresponding to the conference material based on drawing history information of the drawn pointer.

Abstract: Techniques are described for creating a context-aware landing page. A context-aware landing page is capable of dynamically updating its tiles to include content tiles which are related to a received triggering event. The triggering event can be received from a business context source. When the triggering event is received, a weighting table that contains a plurality of content tiles can be retrieved. The method can then select one or more content tiles to include in the context-aware landing page. The selection of the one or more content tiles can depend on the triggering event.

Abstract: The present invention provides an accelerator mass spectrometry device for simultaneously measuring isotopes. In one embodiment, the device comprises a sputtering negative ion source for generating negative ions; the sputtering negative ion source being connected to an accelerating tube for simultaneously accelerating a plurality of isotopic ions; an output end of the accelerating tube being connected to an isotope mass resolution system; the isotope mass resolution system being connected to a charge conversion analysis and multi-receiving measurement system; the charge conversion analysis and multi-receiving measurement system being connected to an ion detection system. The present invention is capable of accelerating a plurality of isotopic negative ions simultaneously. The accelerated isotopic negative ions are separated. Stable isotopic negative ions are measured by a stable isotope receiver. Unstable isotope negative ions are converted to positive ions and then measured by a detector.

Abstract: The present invention provides a fibrinolytic composition useful as a therapeutic for administration to a patient having a thrombotic occlusion. In one aspect of the present invention, the fibrinolytic composition comprises a reversibly inactivated acidified serine protease substantially free of a plasminogen activator, a low buffering capacity buffer, and optionally, a stabilizing agent. In another aspect of the invention, the fibrinolytic composition of the present invention comprises a reversibly inactivated acidified plasmin substantially free of a plasminogen activator, a low buffering capacity buffer, and optionally, a stabilizing agent.

Abstract: Methods for etching a bottom anti-reflective coating (BARC) and/or an anti-reflective coating (ARC) and/or a dielectric anti-reflective coating (DARC) to form high aspect ratio features using an etch process are provided. The methods described herein advantageously facilitate profile and dimension control of features with high aspect ratios through a proper sidewall and bottom management scheme during the bottom anti-reflective coating (BARC) and/or an anti-reflective coating (ARC) and/or a dielectric anti-reflective coating (DARC) open process.

Abstract: An information processing apparatus includes: a memory; and a processor coupled to the memory and configured to execute an acquisition process that includes acquiring a plurality of images which are captured from different positions and include a same feature point, execute a specification process that includes specifying the direction of sight of a user who looks at a panoramic image which is generated based on the plurality of images, and execute a display control process that includes selecting particular images from the plural images based on the direction of sight and displaying the panoramic image composed of the selected particular images.