Patents by Inventor Shan-Yu Chen

Shan-Yu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to produce PHBV by recombinant
    Patent number: 8859246
    Abstract: The invention discloses a method for production of polyhydroxybutyrate-co-polyhydroxyvalerate (PHBV) by recombinant Escherichia coli harboring plasmid containing both phaCAB and prpE. Different percentage of hydroxyvalerate can be obtained from the recombinant E. coli when cultivated in the medium containing different concentrations of propionic acid. In this patent, we provide a method that integrated all of the genes (i.e. phaCAB, vgb and prpE) required for PHBV production into a single plasmid. The plasmids were then transformed into an E. coli host. Results showed that PHBV can be produced by this recombinant E. coli, and the ration of HV to HB in the co-polymers can be regulated by addition of different concentrations of propionic acid in the medium. The percentage of HV in the co-polymers can be adjusted from about 3% up to more than 35%.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: October 14, 2014
    Assignee: Yuan Ze University
    Inventors: Chih-Ching Chien, Po-Chi Soo, Yu-Tze Horng, Shan-Yu Chen, Hsiu-Hsiung Li, Yu-Hong Wei, Wen-Ming Chen
  • Method to Produce PHBV by Recombinant Escherichia Coli
    Publication number: 20130323804
    Abstract: The invention discloses a method for production of polyhydroxybutyrate-co-polyhydroxyvalerate (PHBV) by recombinant Escherichia coli harboring plasmid containing both phaCAB and prpE. Different percentage of hydroxyvalerate can be obtained from the recombinant E. coli when cultivated in the medium containing different concentrations of propionic acid. In this patent, we provide a method that integrated all of the genes (i.e. phaCAB, vgb and prpE) required for PHBV production into a single plasmid. The plasmids were then transformed into an E. coli host. Results showed that PHBV can be produced by this recombinant E. coli, and the ration of HV to HB in the co-polymers can be regulated by addition of different concentrations of propionic acid in the medium. The percentage of HV in the co-polymers can be adjusted from about 3% up to more than 35%.
    Type: Application
    Filed: May 29, 2012
    Publication date: December 5, 2013
    Applicant: YUAN ZE UNIVERSITY
    Inventors: Chih-Ching Chien, Po-Chi Soo, Yu-Tze Horng, Shan-Yu Chen