Patents by Inventor Shane Krummen Atwell

Shane Krummen Atwell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IgG bispecific antibodies and processes for preparation
    Patent number: 11976136
    Abstract: The present invention provides fully IgG bi-specific antibodies comprising designed residues in the interface of the heavy chain-heavy chain (CH3/CH3) domains, processes for preparing said fully IgG bi-specific antibodies, and nucleic acids, vectors and host cells encoding the same.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: May 7, 2024
    Assignees: Eli Lilly and Company, The University of North Carolina at Chapel Hill
    Inventors: Hector Aldaz, Shane Krummen Atwell, Stephen John Demarest, Karen Jean Froning, Brian Arthur Kuhlman, Andrew Philip Leaver-Fay
  • HUMAN INTERLEUKIN-4 RECEPTOR ALPHA ANTIBODY GLUCOCORTICOID CONJUGATES
    Publication number: 20240100176
    Abstract: The present disclosure provides human interleukin 4 receptor alpha antibody glucocorticoid receptor agonist conjugates and methods of using the conjugates for the treatment of inflammatory diseases, such as type 2 inflammatory diseases.
    Type: Application
    Filed: May 31, 2023
    Publication date: March 28, 2024
    Inventors: Shane Krummen Atwell, Joshua R Clayton, Yiqing Feng, Maya Rachel Karta, Donmienne Doen Mun Leung, Songqing Na, Kristin Paige Newburn, Laura Anne Pelletier, Diana Isabel Ruiz, David John Stokell, Jacqueline M Wurst, Scott Paul Bauer
  • Human interleukin-4 receptor alpha antibodies
    Patent number: 11891441
    Abstract: The present disclosure relates to antibodies that specifically bind human IL-4R?, compositions comprising such IL-4R? antibodies, and methods of using such IL-4R? antibodies.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: February 6, 2024
    Assignee: ELI LILLY AND COMPANY
    Inventors: Shane Krummen Atwell, Yiqing Feng, Maya Rachel Karta, Donmienne Leung, Songqing Na, Diana Isabel Ruiz, David John Stokell, Laura Anne Pelletier
  • Crystallization of Antibodies or Antigen-Binding Fragments
    Publication number: 20230137966
    Abstract: Provided herein are methods and compositions for improving the crystallization of antibodies, antigen-binding fragments, e.g., Fab or Fab?, or fusion proteins, and Fab/Fab?/mAb:Antigen complexes.
    Type: Application
    Filed: February 9, 2021
    Publication date: May 4, 2023
    Inventors: Shane Krummen Atwell, Ricky Long Lieu
  • HUMAN INTERLEUKIN-4 RECEPTOR ALPHA ANTIBODIES
    Publication number: 20230064378
    Abstract: The present disclosure relates to antibodies that specifically bind human IL-4R?, compositions comprising such IL-4R? antibodies, and methods of using such IL-4R? antibodies.
    Type: Application
    Filed: August 5, 2022
    Publication date: March 2, 2023
    Inventors: Shane Krummen ATWELL, Yiqing FENG, Maya Rachel KARTA, Donmienne LEUNG, Songqing NA, Diana Isabel RUIZ, David John STOKELL, Laura Anne Pelletier
  • BTLA agonist antibodies and uses thereof
    Patent number: 11396545
    Abstract: Antibodies which bind BTLA, and methods of using same, are provided, said antibodies are useful as agents for treating conditions associated with autoimmune disease including treating lupus.
    Type: Grant
    Filed: February 17, 2020
    Date of Patent: July 26, 2022
    Assignee: Eli Lilly and Company
    Inventors: Shane Krummen Atwell, Andrew Charles Vendel, Victor H. Obungu
  • IgG Bispecific Antibodies and Processes for Preparation
    Publication number: 20210054103
    Abstract: The present invention provides fully IgG bi-specific antibodies comprising designed residues in the interface of the heavy chain-heavy chain (CH3/CH3) domains, processes for preparing said fully IgG bi-specific antibodies, and nucleic acids, vectors and host cells encoding the same.
    Type: Application
    Filed: July 17, 2020
    Publication date: February 25, 2021
    Inventors: Hector ALDAZ, Shane Krummen ATWELL, Stephen John DEMAREST, Karen Jean FRONING, Brian Arthur KUHLMAN, Andrew Philip LEAVER-FAY
  • IgG bispecific antibodies and processes for preparation
    Patent number: 10774156
    Abstract: The present invention provides fully IgG bi-specific antibodies comprising designed residues in the interface of the heavy chain-heavy chain (CH3/CH3) domains, processes for preparing said fully IgG bi-specific antibodies, and nucleic acids, vectors and host cells encoding the same.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: September 15, 2020
    Assignees: Eli Lilly and Company, The University of North Carolina at Chapel Hill
    Inventors: Hector Aldaz, Shane Krummen Atwell, Stephen John Demarest, Karen Jean Froning, Brian Arthur Kuhlman, Andrew Philip Leaver-Fay
  • BTLA AGONIST ANTIBODIES AND USES THEREOF
    Publication number: 20200239578
    Abstract: Antibodies which bind BTLA, and methods of using same, are provided, said antibodies are useful as agents for treating conditions associated with autoimmune disease including treating lupus.
    Type: Application
    Filed: February 17, 2020
    Publication date: July 30, 2020
    Inventors: Shane Krummen Atwell, Andrew Charles Vendel, Victor H. Obungu
  • BTLA agonist antibodies and uses thereof
    Patent number: 10604573
    Abstract: Antibodies which bind BTLA, and methods of using same, are provided, said antibodies are useful as agents for treating conditions associated with autoimmune disease including treating lupus.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: March 31, 2020
    Assignee: Eli Lilly and Company
    Inventors: Shane Krummen Atwell, Andrew Charles Vendel, Victor H. Obungu
  • BTLA AGONIST ANTIBODIES AND USES THEREOF
    Publication number: 20180334502
    Abstract: Antibodies which bind BTLA, and methods of using same, are provided, said antibodies are useful as agents for treating conditions associated with autoimmune disease including treating lupus.
    Type: Application
    Filed: May 11, 2018
    Publication date: November 22, 2018
    Inventors: Shane Krummen Atwell, Andrew Charles Vendel, Victor H. Obungu
  • IgG Bispecific Antibodies and Processes for Preparation
    Publication number: 20180009908
    Abstract: The present invention provides fully IgG bi-specific antibodies comprising designed residues in the interface of the heavy chain-heavy chain (CH3/CH3) domains, processes for preparing said fully IgG bi-specific antibodies, and nucleic acids, vectors and host cells encoding the same.
    Type: Application
    Filed: January 21, 2016
    Publication date: January 11, 2018
    Applicants: Eli Lilly and Company, The University of North Carolina at Chapel Hill
    Inventors: Hector Aldaz, Shane Krummen Atwell, Stephen John Demarest, Karen Jean Froning, Brian Arthur Kuhlman, Andrew Philip Leaver-Fay