Patents by Inventor Shane MORLEY

Shane MORLEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of alpha-tubulin acetylation for the treatment of pain
    Patent number: 11834713
    Abstract: The present invention pertains to novel analgesics useful for treating mechanical pain. The invention suggests the use of inhibitors of ?-tubulin acetylation for inhibition of neurological sensations that are mediated by sensory neurons. The perception of mechanical pain is can be modulated by altering the ?-tubulin acetylation, in context of the invention in particular by modulation of the expression and/or activity of the enzyme ?-tubulin acetyltransferase (Atat). The invention provides the medical application of ?-tubulin acetyltransferase inhibitors as analgesics and a screening method for the identification of compounds useful in the treatment of pain.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: December 5, 2023
    Assignee: EUROPEAN MOLECULAR BIOLOGY LABORATORY
    Inventors: Paul Heppenstall, Shane Morley
  • INHIBITORS OF ALPHA-TUBULIN ACETYLATION FOR THE TREATMENT OF PAIN
    Publication number: 20220002801
    Abstract: The present invention pertains to novel analgesics useful for treating mechanical pain. The invention suggests the use of inhibitors of ?-tubulin acetylation for inhibition of neurological sensations that are mediated by sensory neurons. The perception of mechanical pain is can be modulated by altering the ?-tubulin acetylation, in context of the invention in particular by modulation of the expression and/or activity of the enzyme ?-tubulin acetyltransferase (Atat). The invention provides the medical application of ?-tubulin acetyltransferase inhibitors as analgesics and a screening method for the identification of compounds useful in the treatment of pain.
    Type: Application
    Filed: July 23, 2021
    Publication date: January 6, 2022
    Inventors: Paul HEPPENSTALL, Shane MORLEY
  • Inhibitors of ?-tubulin acetylation for the treatment of pain
    Patent number: 11104949
    Abstract: The present invention pertains to novel analgesics useful for treating mechanical pain. The invention suggests the use of inhibitors of ?-tubulin acetylation for inhibition of neurological sensations that are mediated by sensory neurons. The perception of mechanical pain is can be modulated by altering the ?-tubulin acetylation, in context of the invention in particular by modulation of the expression and/or activity of the enzyme ?-tubulin acetyltransferase (Atat). The invention provides the medical application of ?-tubulin acetyltransferase inhibitors as analgesics and a screening method for the identification of compounds useful in the treatment of pain.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: August 31, 2021
    Assignee: European Molecular Biology Laboratory
    Inventors: Paul Heppenstall, Shane Morley
  • INHIBITORS OF ALPHA-TUBULIN ACETYLATION FOR THE TREATMENT OF PAIN
    Publication number: 20190024170
    Abstract: The present invention pertains to novel analgesics useful for treating mechanical pain. The invention suggests the use of inhibitors of ?-tubulin acetylation for inhibition of neurological sensations that are mediated by sensory neurons. The perception of mechanical pain is can be modulated by altering the ?-tubulin acetylation, in context of the invention in particular by modulation of the expression and/or activity of the enzyme ?-tubulin acetyltransferase (Atat). The invention provides the medical application of ?-tubulin acetyltransferase inhibitors as analgesics and a screening method for the identification of compounds useful in the treatment of pain.
    Type: Application
    Filed: December 28, 2016
    Publication date: January 24, 2019
    Inventors: Paul HEPPENSTALL, Shane MORLEY