Abstract: Devices and methods for measuring a concentration of a target analyte in a biological fluid in vivo are provided herein. In some examples, a device includes an indwelling sensor and sensor electronics. The sensor may include a substrate; a first electrode disposed on the substrate; an ionophore disposed on the substrate to selectively transport the target ion to or within the first electrode; and a second electrode disposed on the substrate. The sensor electronics is configured to generate a signal corresponding to an electromotive force which is at least partially based on a potential difference that is generated between the first electrode and the second electrode responsive to the ionophore transporting the target ion to the first electrode.

Abstract: Disclosed herein are systems and methods for a continuous analyte monitoring system for measuring a concentration of a first analyte and concentration of a second analyte in a host. One such system utilizes a working electrode and a reference electrode to measure glucose concentration and oxygen concentration in bodily fluid of a host. The system includes a sensor control circuit that applies a first bias condition to the sensor to measure a first signal generated by the sensor indicative of a concentration of the first analyte. The sensor control circuit also applies a second bias condition to the sensor to measure a second signal generated by the sensor indicative of a concentration of a second analyte at the host.

Abstract: This invention discloses a method for controlling nanoscopic wetting near or at a molecular scale for synthetic material applications. In particular this invention relates to a method for preparing a monolayer or thin film with a patterned nanoscopic wetting surface using a ‘sitting’ phase of polymerizable amphiphile, wherein hydrophobic alkyl chains of the amphiphile extend along the supporting surface and the amphiphile molecules align side-to-side, effectively forming a repeating cross-section of bilayer with alternating hydrophilic and hydrophobic stripes of a ˜6 nm pitch tunable based on the chain length of the amphiphile. Products prepared according to the methods disclosed herein are within the scope of this invention. In some embodiments, monolayers or thin films so prepared are transferable.

Abstract: The present disclosure relates generally to bioactive releasing membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the disclosure relates to novel bioactive releasing membranes, to devices and implantable devices including these membranes, methods for forming the bioactive releasing membranes on or around the implantable devices, and to methods for monitoring analyte levels in a biological fluid sample using an implantable analyte detection device.

Abstract: The present disclosure relates generally to drug releasing membranes utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, the disclosure relates to novel drug releasing membranes, to devices and implantable devices including these membranes, methods for forming the drug releasing membranes on or around the implantable devices, and to methods for monitoring analyte levels in a biological fluid sample using an implantable analyte detection device.

Abstract: A tracking device includes a housing that can be mounted to a patient or a prosthetic device or orthotic device of the patient. The tracking device can include communications circuitry, a position sensor, and processing circuitry. The position sensor is configured to detect position data regarding the patient. The processing circuitry is configured to receive the position data from the position sensor, determine one or more metrics regarding activity of the patient based on the position data, and use the communications circuitry to transmit at least one of the position data or the one or more metrics to a client device via the cellular network.

Abstract: A non-invasive sensing system for measuring the concentration of a substance within an object, the system including a support element adapted to be placed near to, or against, a surface of the object, a first transmitting antenna mounted upon or within the support element for transmitting electromagnetic radiation signals into the object, and a second receiving antenna mounted upon or within the support element, and adjacent to the first transmitting antenna, for receiving at least a portion of the electromagnetic radiation signals that are reflected back to the same surface of the object covered by the support element, due to the transmitted electromagnetic radiation signals having interacted with the substance within the object being measured.

Abstract: This invention generally relates to a method for modulating interfacial wettability of a noncovalent nanoscopic monolayer or thin film. Particularly, this invention relates to a method for modulating interfacial wettability of a two-dimensional (2D) material using a molecular layer prepared from a polymerizable amphiphilic monomer having a hydrophilic head and a hydrophobic tail, wherein enhanced or decreased wettability of said 2D material is achieved by proper allocating the position of polymerizable group relative to the hydrophilic head and the hydrophobic tail.

Abstract: A system for monitoring a component part of a top drive in real time comprises a top drive, one or more operating sensors coupled to the top drive, and an onboard processing transceiver coupled to the top drive and in communication with the operating sensors. The operating sensors are configured to measure operational data of the top drive during operation. The onboard processing transceiver is configured to determine a remaining life of the component part.

Abstract: A system configured to predict and optimize operating life of a piece of drilling equipment includes a plurality of operating sensors coupled to a piece of drilling equipment, wherein each of the operating sensors is configured to measure an operating condition of the piece of drilling equipment. A control system in communication with the operating sensors is configured to calculate an operating life of the piece of equipment based on the operating conditions.

Abstract: A system for monitoring a consumable part of a piece of equipment in real time comprises a piece of equipment, one or more operating sensors coupled to the piece of equipment, and an onboard processing transceiver coupled to the piece of equipment and in communication with the operating sensors. The operating sensors are configured to measure operational data of the piece of equipment during operation. The onboard processing transceiver is configured to determine a remaining life of the consumable part.

Abstract: This invention discloses a method for controlling nanoscopic wetting near or at a molecular scale for synthetic material applications. In particular this invention relates to a method for preparing a monolayer or thin film with a patterned nanoscopic wetting surface using a ‘sitting’ phase of polymerizable amphiphile, wherein hydrophobic alkyl chains of the amphiphile extend along the supporting surface and the amphiphile molecules align side-to-side, effectively forming a repeating cross-section of bilayer with alternating hydrophilic and hydrophobic stripes of a ˜6 nm pitch tunable based on the chain length of the amphiphile. Products prepared according to the methods disclosed herein are within the scope of this invention. In some embodiments, monolayers or thin films so prepared are transferable.

Abstract: This invention generally relates to a method for modulating interfacial wettability of a noncovalent nanoscopic monolayer or thin film. Particularly, this invention relates to a method for modulating interfacial wettability of a two-dimensional (2D) material using a molecular layer prepared from a polymerizable amphiphilic monomer having a hydrophilic head and a hydrophobic tail, wherein enhanced or decreased wettability of said 2D material is achieved by proper allocating the position of polymerizable group relative to the hydrophilic head and the hydrophobic tail.

Abstract: A drilling equipment tracking system includes a piece of drilling equipment and a traceability tag coupled to the piece of drilling equipment. The traceability tag has a unique identifier. A mobile device is configured to obtain the unique identifier and access a remote server containing an equipment file corresponding to the piece of drilling equipment based on the unique identifier.

Abstract: A non-invasive sensing system for measuring the concentration of a substance within an object, the system including a support element adapted to be placed near to, or against, a surface of the object, a first transmitting antenna mounted upon or within the support element for transmitting electromagnetic radiation signals into the object, and a second receiving antenna mounted upon or within the support element, and adjacent to the first transmitting antenna, for receiving at least a portion of the electromagnetic radiation signals that are reflected back to the same surface of the object covered by the support element, due to the transmitted electromagnetic radiation signals having interacted with the substance within the object being measured.

Abstract: A drilling equipment tracking system includes a piece of drilling equipment and a traceability tag coupled to the piece of drilling equipment. The traceability tag has a unique identifier. A mobile device is configured to obtain the unique identifier and access a remote server containing an equipment file corresponding to the piece of drilling equipment based on the unique identifier.

Abstract: A system configured to predict and optimize operating life of a piece of drilling equipment includes a plurality of operating sensors coupled to a piece of drilling equipment, wherein each of the operating sensors is configured to measure an operating condition of the piece of drilling equipment. A control system in communication with the operating sensors is configured to calculate an operating life of the piece of equipment based on the operating conditions.

Abstract: Systems, methods, and devices use a wireless device's capability to transmit and/or receive data over multiple communication pathways to improve data transmission quality. In the various embodiments, the same continuous data stream may be transmitted and/or received via different communication pathways. Different communication pathways may be established using different antennas of a wireless device, different wireless networks, different wireless communications protocols, and/or additional wireless devices. The continuous data stream may be transmitted and/or received via different communication pathways in a manner that enables the continuous data stream to be reconstructed from one or more of the different communication pathways. Additional communication pathways may be established based on user input indicating a voice call is high priority and/or approving the expenditure of additional resources.

Abstract: A method of designing an optimized heating and cooling system includes: (1) simulating energy use of a virtual heating and cooling system operating a first potential thermal source or sink under a plurality of conditions; (2) simulating energy use of the virtual heating and cooling system operating a second potential thermal source or sink under a plurality of conditions; (3) optimizing the energy use of the virtual system operating the first potential thermal source or sink or the second potential thermal source or sink using neural network optimization; and (4) designing a heating and cooling system based upon the optimization of the energy use of the virtual system.

Abstract: In an embodiment, an application server receives, from a given UE, data that is configured to visually represent physical user input detected at the given UE at a first level of precision. The application server determines data presentation capabilities of a target UE and/or a performance level associated with a connection between the application server and the target UE. The application server selectively transitions the received data from the first level of precision to a second level of precision based on the determination, and transmits the selectively transitioned data to the target UE for presentation. In another embodiment, the application server receives a request to adjust display settings of the target UE from the given UE responsive to detected physical user input. The application server selectively adjusts the target UE's display settings based on the received request.