Patents by Inventor Shane T. Grosser

Shane T. Grosser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immobilized transaminases and process for making and using immobilized transaminase
    Patent number: 9523107
    Abstract: The invention is directed to immobilized transaminases and methods of making and using them.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: December 20, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Matthew D. Truppo, Michel Journet, Hallena Strotman, Jonathan P. McMullen, Shane T. Grosser
  • Transiently bonding drag-tags for separation modalities
    Patent number: 9221863
    Abstract: The invention relates transiently attaching drag-tags to molecules during electrophoresis. The invention includes running buffers having drag-tags that transiently attach to lipophilic moieties attached to the molecules. The lipophilic moieties can be covalently or ionically bonded to the molecules. One particular aspect of the invention is a nucleoside analog or a nucleic acid analog comprising a lipophilic moiety. The invention is also directed to methods of separating molecules that comprise a lipophilic moiety. The methods generally comprise transiently attaching a drag-tag to the lipophilic moiety during a separation modality. These methods can be used to separate the molecules by size or weight, to measure a hydrodynamic radius of a drag-tag, or to separate a plurality of drag-tag by their hydrodynamic radius.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: December 29, 2015
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: James W. Schneider, Shane T. Grosser, Jeffrey M. Savard
  • IMMOBILIZED TRANSAMINASES AND PROCESS FOR MAKING AND USING IMMOBILIZED TRANSAMINASE
    Publication number: 20150368682
    Abstract: The invention is directed to immobilized transaminases and methods of making and using them.
    Type: Application
    Filed: February 24, 2014
    Publication date: December 24, 2015
    Inventors: Matthew D. Truppo, Michel Journet, Hallena Strotman, Jonathan P. McMullen, Shane T. Grosser
  • TRANSIENTLY BONDING DRAG-TAGS FOR SEPARATION MODALITIES
    Publication number: 20100213059
    Abstract: The invention relates transiently attaching drag-tags to molecules during electrophoresis. The invention includes running buffers having drag-tags that transiently attach to lipophilic moieties attached to the molecules. The lipophilic moieties can be covalently or ionically bonded to the molecules. One particular aspect of the invention is a nucleoside analog or a nucleic acid analog comprising a lipophilic moiety. The invention is also directed to methods of separating molecules that comprise a lipophilic moiety. The methods generally comprise transiently attaching a drag-tag to the lipophilic moiety during a separation modality. These methods can be used to separate the molecules by size or weight, to measure a hydrodynamic radius of a drag-tag, or to separate a plurality of drag-tag by their hydrodynamic radius.
    Type: Application
    Filed: June 23, 2008
    Publication date: August 26, 2010
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: James W. Schneider, Shane T. Grosser, Jeffrey M. Savard