Patents by Inventor Shang-pin Kwei

Shang-pin Kwei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vessel for growth of biological entities
    Patent number: 10870822
    Abstract: A 5-liter bioreactor vessel enables a substantial increase in the volume of biological media that can be cultivated in the vessel compared to conventional designs. Moreover, when agitated at 1.5× the shaking frequency of a conventional 3-liter bioreactor (i.e., 90 rpm versus 60 rpm), the 5-liter vessel achieves a 19% increase in cell aeration without exceeding the maximum shear stress limit for cell viability. The 5-liter vessel optionally includes a plurality of internal baffles configured to disrupt the liquid vortex and reduce the maximum shear stress transferred to biomedia contained within the vessel.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: December 22, 2020
    Assignee: Corning Incorporated
    Inventors: David Alan Kenney, Nikolaos Pantelis Kladias, Shang-Pin Kwei, Aravind Raghavan Rammohan, Joseph Christopher Wall, Kathy Marie Youngbear
  • VESSEL FOR GROWTH OF BIOLOGICAL ENTITIES
    Publication number: 20170037350
    Abstract: A 5-liter bioreactor vessel enables a substantial increase in the volume of biological media that can be cultivated in the vessel compared to conventional designs. Moreover, when agitated at 1.5× the shaking frequency of a conventional 3-liter bioreactor (i.e., 90 rpm versus 60 rpm), the 5-liter vessel achieves a 19% increase in cell aeration without exceeding the maximum shear stress limit for cell viability. The 5-liter vessel optionally includes a plurality of internal baffles configured to disrupt the liquid vortex and reduce the maximum shear stress transferred to biomedia contained within the vessel.
    Type: Application
    Filed: April 9, 2015
    Publication date: February 9, 2017
    Inventors: David Alan Kenney, Nikolaos Pantelis Kladias, Shang-Pin Kwei, Aravind Raghavan Rammohan, Joseph Christopher Wall, Kathy Marie Youngbear
  • Methods for Producing Tissue Scaffold Directing Differentiation of Seeded Cells and Tissue Scaffolds Produced Thereby
    Publication number: 20130316454
    Abstract: Methods for producing a tissue scaffold which direct differentiation of seeded stem cells on the scaffold to a selected cell type and tissue scaffolds produced thereby are provided.
    Type: Application
    Filed: June 22, 2011
    Publication date: November 28, 2013
    Inventors: Helen H. Lu, Shang-pin Kwei, Natalie L. Leong, Marissa R. Solomon, Siddarth D. Subramony