Patents by Inventor Shangang Zhao

Shangang Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Weight Loss Regimen
    Publication number: 20240034782
    Abstract: Obesity and/or diabetes are treated by partially inhibiting circulating leptin in a person in need thereof.
    Type: Application
    Filed: August 5, 2023
    Publication date: February 1, 2024
    Applicant: Board of Regents, The University of Texas System
    Inventors: Philipp E. Scherer, Shangang Zhao
  • Leptin Antibodies
    Publication number: 20230374126
    Abstract: Antibody antigen binding domains which specifically binds human leptin comprises VH or VL CDR1, CDR2 and CDR3 sequences of an hLept antibody. The antibody antigen binding domains and antibodies thereof are useful to treat obesity and diabetes.
    Type: Application
    Filed: August 4, 2023
    Publication date: November 23, 2023
    Applicant: Board of Regents, The University of Texas System
    Inventors: Zhiqiang An, Ningyan Zhang, Philipp E. Scherer, Shangang Zhao
  • THERAPEUTIC AGENTS AND USES THEREOF
    Publication number: 20230348586
    Abstract: The present disclosure relates generally to therapeutic agents and related uses thereof, including, agents for reducing leptin in a patient or subject and methods of treatment thereof. The therapeutic agents can comprise (without limitation), an antibody or specific binding fragment thereof, a leptin antagonist, a leptin targeting antisense oligonucleotide, a leptin targeting small interfering RNA (siRNA), a leptin targeting short hairpin RNA (shRNA), and/or a gene editing composition directed to at least one target sequence of a leptin polynucleotide. The therapeutic agents can be used in various methods of treatment, including (without limitation), treating liver fibrosis, cancer, inducing or maintaining weight loss, reducing or preventing weight gain, and increasing insulin sensitivity, among others.
    Type: Application
    Filed: September 21, 2021
    Publication date: November 2, 2023
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Phillipp E. SCHERER, Shangang ZHAO, Zhiqiang AN, Ningyan ZHANG
  • Leptin antibodies
    Patent number: 11760799
    Abstract: Antibody antigen binding domains which specifically binds human leptin comprises VH or VL CDR1, CDR2 and CDR3 sequences of an hLept antibody. The antibody antigen binding domains and antibodies thereof are useful to treat obesity and diabetes.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: September 19, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Zhiqiang An, Ningyan Zhang, Philipp E. Scherer, Shangang Zhao
  • Weight loss regimen
    Patent number: 11732037
    Abstract: Obesity and/or diabetes are treated by partially inhibiting circulating leptin in a person in need thereof.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: August 22, 2023
    Assignee: Board of Regents, The University of Texas Svstem
    Inventors: Philipp E. Scherer, Shangang Zhao
  • Weight Loss Regimen
    Publication number: 20210395359
    Abstract: Obesity and/or diabetes are treated by partially inhibiting circulating leptin in a person in need thereof.
    Type: Application
    Filed: December 16, 2020
    Publication date: December 23, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Philipp E. Scherer, Shangang Zhao
  • Leptin Antibodies
    Publication number: 20210188970
    Abstract: Antibody antigen binding domains which specifically binds human leptin comprises VH or VL CDR1, CDR2 and CDR3 sequences of an hLept antibody. The antibody antigen binding domains and antibodies thereof are useful to treat obesity and diabetes.
    Type: Application
    Filed: December 16, 2020
    Publication date: June 24, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Zhiqiang An, Ningyan Zhang, Philipp E. Scherer, Shangang Zhao