Patents by Inventor Shangxi Xiao

Shangxi Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peripherin and Neurofilament Light Protein Splice Variants in Amyotrophic Lateral Sclerosis (ALS)
    Publication number: 20090053723
    Abstract: Nucleotide sequences encoding novel splice variants of peripherin and neurofilament light protein, proteins encoded by the novel splice variants and antibodies thereto are disclosed. In addition, methods are described for detecting ALS in a subject suspected of having ALS, comprising detecting the presence or absence of the novel splice variants or resulting proteins or a change in the amount of the novel splice variants or resulting proteins; wherein the presence or change in the amount of the nucleotide sequence is indicative of ALS.
    Type: Application
    Filed: August 22, 2008
    Publication date: February 26, 2009
    Inventors: Shangxi Xiao, Janice Robertson
  • Method of diagnosing and treating dentinogenesis imperfecta type II by using dentin sialophosphoprotein gene and coded product thereof
    Patent number: 7396644
    Abstract: The invention has disclosed a method for diagnosis of dentinogenesis imperfecta type II (DGI-II) and/or dentinogenesis imperfecta type II with deafness (DGI-II with deafness). Said method comprises the steps of detecting the DSPP gene, transcript and/or protein in said subject and comparing it with the normal DSPP gene, transcript and/or protein to determine whether there is any variation, wherein said variation indicates that the possibility of suffering DGI-II and/or DGI-II with deafness in said subject is higher than the normal population. The present invention also discloses the method and pharmaceutical composition for treating DGI-II and/or DGI-II with deafness.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: July 8, 2008
    Assignee: Shanghai Institutes of Biological Science, Chinese Academy of Science
    Inventors: Xiangyin Kong, Shangxi Xiao, Guoping Zhao, Chuan Yu, Landian Hu
  • Method for diagnosing and treating dentinogenesis imperfecta type II by using dentin sialophsphoprotein (dspp)gene and its encoding product
    Publication number: 20030180280
    Abstract: The invention has disclosed a method for diagnosis of dentinogenesis imperfecta type II (DGI-II) and/or dentinogenesis imperfecta type II with deafness (DGI-II with deafness). Said method comprises the steps of detecting the DSPP gene, transcript and/or protein in said subject and comparing it with the normal DSPP gene, transcript and/or protein to determine whether there is any variation, wherein said variation indicates that the possibility of suffering DGI-II and/or DGI-II with deafness in said subject is higher than the normal population. The present invention also discloses the method and pharmaceutical composition for treating DGI-II and/or DGI-II with deafness.
    Type: Application
    Filed: March 5, 2003
    Publication date: September 25, 2003
    Inventors: Xiangyin Kong, Shangxi Xiao, Guoping Zhao, Chuan Yu, Landian Hu